Scientist/Specialist - Research & Development (Analytical development)

About Immuneel

Immuneel Therapeutics Private Limited is a pioneering start-up company leading the charge in cell therapy and personalized immunotherapy for patients in India. For more details, please refer www.immuneel.com

We Pursue, with Purpose, to serve our Patients (3 Ps) by Connecting within, collaborating globally and Creating (3 Cs) solutions. Our flexible, diverse, and vibrant team is bringing together best practices and innovations in the field of cell and gene therapy.

Working at Immuneel promises the excitement of an agile startup on a critical mission. Proudly Indian in solutioning, yet global in outlook, we are keen to collaborate. We value diversity including in experience and perspectives. We value work-life balance and believe that having fun on the job is integral to achieving the right results. We pride ourselves on providing an open environment and our mission resonates with humanity everywhere. At Work, we are:

• Passionate in driving patient outcomes:

  We are passionately committed to doing the RIGHT thing to achieve the best outcomes for our patients through innovation, agility and performance orientation. We put the impact on the patient above all else.

• Responsible and accountable:

  We demonstrate ownership and accountability for our actions. We make timely and well-informed decisions, learning from our performance.

• Transparent, honest, and supportive in how we work together:

  We insist on integrity and respect for the individual. We demand excellence. Our performance management is focused on excellence through timely and constructive feed-forward.

• Inclusive and flexible:

  We are full of life and embrace all opportunities to collaborate and work together. We are excited about the collective knowledge and expertise that we share. “Being and thinking different” is valued.

Immuneel prides itself as an organization that is keeping pace with best practices in organization design. Our role-based organization incorporates global trends in human capital that promote focus on work and greater nimbleness. Our role-based structure allows you to be cherished by the work you do and bring value to your work rather than designations, our organization is simplified into a flat, non-hierarchical, millennial, organization where you may fully inherit the role you play in the organization and are recognized by the accountability you take and the work you deliver.

Immuneel’s employees are integral to our quest to develop and deliver high quality engineered cell therapies in India. We believe that our culture provides an environment for employees to excel and find purpose. The strength of our team is every bit as important as our cutting-edge technology and we invest in clear compensation and comprehensive benefits for our employees. People for us, are not resources, but our capital.

If you are a talented professional, an out-of-box thinker with a zeal to help change, and passionate about healthcare, we invite you to join us and be a part of a historic initiative in India.

careers@immuneel.com

1. Role Title:

Scientist/Specialist - Research & Development (Analytical development)

2. Department/Function:

Research & Development

3. Reporting Structure:

Reports to:

• Dotted Reporting to:

  NA

• Direct Reports:

  NA

4. Role Summary:

The person under this hybrid role will support development, qualification & tech transfer of Analytical assays for product release or translational research for patient monitoring. . The role shall enable compliant & Smooth Analytical development for R&D programs and Clinical Trial Data generation.

5. Key Responsibilities:

1. Drive molecular biology Assay method development for both qualitative and quantitative gene expression analysis.

1. Independently able to develop the assays on the advanced molecular biology instruments like qPCR, ddPCR, dPCR and Transfer to QC for various R&D programs.

1. Independently able to develop and validate ELISA based methods for Viral vectors and CAR T product release and knowledge transfer to R&D colleagues and QC.

1. Drive the development and validate different cell-based assays for various in-house programs and transfer to QC.

1. Executing Molecular and cell biology assays on Clinical trial samples as well as samples from other R&D Programs (Eg. ddPCR, Flow cytometry, other cell-based assays).

1. Analysis & Reporting of Data generated from various assays.

1. Industry standard Documentation: Experimental records, Protocols & Reports. Support XOP generation and closure of change controls, CAPA etc. were required.

1. Ordering of reagents, consumables & inventory management.

1. Equipment management: Support purchase & maintenance of equipment and associated documentation, co-ordination with Lab manager, FAO, QA for same.

6. Primary Objectives:

1. Drive Analytical Development for various R&D programs to take them to the next stage.
2. Work cross-functionally to drive Translational Assay development and Support Data generation.

7. Competencies Required:

• Technical Competencies:

1. Experience in cloning
2. Experience in developing molecular biology and protein biology
3. Experience in developing qPCR/d PCR/ddPCR based assays
4. Handling virus cultures
5. Strong molecular and Immunology domain knowledge
6. Experience in handing primary cells of hematological origin (PBMCs, T cells, B cells, etc.)
7. Experience in developing ELISA based assays
8. Experience in handling cell lines
9. Experience in routine molecular biology techniques
10. Excellent documentation & Inventorisation skills
11. Experience in NGS based assays shall be a plus.
12. Basic Statistical & Data analysis skills.

• Soft Skills:

1. Basic IT skills. Expert with MS Office (Excel, word).
2. Good communication skills.
3. Independent but Team player.
4. Adaptable & Collaborative.
5. Organized & Quality commitment.
6. Self-confident & Resourceful
7. Analytical & Problem solver
8. Detail oriented & Conceptual
9. Enthusiastic & Committed.
10. Hard working & Continuous learner.

8. Qualifications:

1. Masters degree (MSc, MS, MTech) in Life sciences, Biotech or related fields with 5-10 years of industry experience.
2. PhD with experience in patient sample handling. (2–5-year industry experience).

9. Working Conditions:

• Role Type:

  Full Time and Onsite

• Work Hours:

  9:00 AM to 6:00 PM for the General Shift and 2:00 PM to 11:00 PM for the Post-Noon Shift (on a rotational basis, may also require coming in shifts based on the requirement). There will be two days off each week, which may not necessarily fall on a Saturday or Sunday.

• Travel Requirements:

  No

• Base Location:

  Immuneel Therapeutics Private Limited, 8th Floor, Mazumdar Shaw Medical Center, Narayana Health City, Bommasandra Industrial Area, Bangalore - 560099