Head Pharmacology

20 years

0 Lacs

Posted:16 hours ago| Platform: GlassDoor logo

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Work Mode

On-site

Job Type

Part Time

Job Description

Position Description

Business Division: PIHS Discovery Services

Department: Biology

Location: HYD


Position Title: Head - Biology

Level: S4

Reporting to (Title): CSO


Position Purpose

Strategic Responsibilities

Operational Responsibilities

  • Build and lead a discovery biology group with capabilities to execute integrated drug discovery projects, including discovery in vitro pharmacology, biochemistry, immunology, protein sciences, structural biology, in vivo, translational and cell biology.
  • Responsible for the target identification, discovery, and pre-clinical development leading to new clinical candidates.
  • Actively provide creative and innovative leadership for discovery biology enabling project progress from biological hypotheses into transformative medicines.
  • Enable the creation of various target related in vitro assays and provide necessary support for the development of in vivo models and pharmacology experiments in support of program objectives.
  • Expand the company's external network through identification/recommendation of thought leaders and advisors to the CSO and establish deep domain area expertise in program areas such as immunology/inflammation, immuno-oncology, autoimmunity and inflammation.
  • Construct and manage spending budgets and project resourcing.
  • Responsible for identifying and building lab infrastructure to support a high-throughput discovery engine equipped with digital data processing and communication (eLNB and LIMs).
  • Keep up-to-date with the latest therapeutic modalities, scientific advances, technologies, and trends in and development to deliver the next generation of therapies.
  • Explore academia collaborations to enhance innovative approaches for drug screening.
  • Work closely with BD and Sales team to ensure “win outcomes” for proposals/RFP for FTE and FFS projects submissions.
  • Ensure seamless integration with project management team and scientific teams to achieve excellence in delivering project related milestones with high data credibility with an “ON TIME-EVERYTIME” and ALCOA+ Principles for Data Integrity in Life Sciences.
  • Ensure data integrity, following all the SOPs and guidelines as per ALCHOA principles.
  • Ensure safety regulations and implemented in accordance with company’s safety regulations to achieve “zero tolerance” policy.

Financial Responsibilities

  • Preparation of annual/five year CAPEX and FTE utilisation/projections keeping in mind the company and departmental objectives.
  • Ensure Discovery Biology teams adhere to budget (CAPEX/REVEX) as required by the project.
  • Determine appropriate FTE/FFS rates for client proposals after through due diligence.
  • Work closely with BD and Sales teams and oversee scientific proposal preparation, RFP preparation and submissions in alignment with company policies.
  • Work closely with BD and Project management teams to track milestones, timelines and revenues with focus on proposal cost and pricing (to maximise P&L).

People Responsibilities

  • Build and lead a strong team of directors, scientists, and RAs in in vitro, in vivo, ADME and translational sciences, to achieve company milestones.
  • Enable the Discovery Biology team to collaborate closely with, chemistry, and DMPK groups to drive discovery and lead optimization and pre-clinical characterization of multiple projects across discovery programs.
  • Support and ensure effective interaction and communication between Biology, Chemistry, and DMPK teams, in alignment client requirements and leadership teams.
  • Interact with all stakeholders to enable timely and accurate communication on project progress towards meeting project goals and timelines.

Education Qualification

A proven scientific leader with a Ph.D. in Immunology/Biology/Biochemistry/Cell Biology
20+ years of biotechnology and pharmaceutical drug discovery R&D experience.

Work Experience

  • Demonstrated strong leadership and team management skills with experience in building and retaining high-performing scientific teams, with an ability to work within a matrixed structure across the drug discovery continuum.
  • Therapeutic domain expertise in immunology, oncology, inflammation and autoimmunity and rare diseases with extensive experience in CRO management in these therapeutic areas.


Industry to be Hired from

Pharma/CRO/CDMO

Functional Competencies

  • Teamwork & Collaboration
  • Should have a proven track record of successfully advancing therapeutic programs from early discovery through to CCN
  • Should possess outstanding interpersonal, collaborative and operational skills with experience guiding and motivating successful teams and building leaders for the organisation aligned with company goals and vision
  • A demonstrated ability to think logically and critically and to develop innovative approaches to answering complex biological questions
  • Passion for identifying and implementing latest technologies and modalities driving drug discovery in the pharma industry

Interaction Complexity and Team Work

Interaction Complexity & Team work


Interaction
Frequency

Purpose of Interaction


Internal :
    • Senior management and team

As and when required

Operational insight, financials, project status.

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