Molecular Biologist

Job Description

Job Title: Molecular Biologist – qPCR Consultant (Preclinical – In Vitro) Location: MS Clinical Research Pvt Ltd (MSCR) Department: Preclinical – In Vitro Employment Type: Consultant/ Part- time Experience: Minimum 10 years in Molecular Biology with hands-on expertise in qPCR Role Overview: MSCR is seeking an accomplished Molecular Biologist – qPCR Consultant to support our preclinical (in-vitro) research team. The ideal candidate will bring deep technical expertise in qPCR assay development, optimization, and data analysis, specifically aligned with preclinical drug screening and mechanistic in-vitro studies. This is a strategic consulting role aimed at enhancing our molecular biology capabilities in gene expression, target validation, and biomarker discovery. Key Responsibilities: Provide technical leadership in the design, development, and validation of qPCR assays for in-vitro studies including cytotoxicity, gene expression profiling, and pathway analysis. Advise on sample preparation, RNA/DNA extraction, and quality control specific to in-vitro systems (e.g., cell lines, primary cultures). Guide the team in primer/probe design, assay optimization (SYBR/TaqMan), and standard curve generation. Troubleshoot experimental issues and recommend improvements to protocols and workflows. Ensure robust data integrity, statistical soundness, and scientific documentation of qPCR results. Review experimental designs to align with regulatory and scientific requirements for GLP-compliant preclinical studies. Train lab scientists on best practices for qPCR technique and data interpretation. Collaborate with research scientists and study directors to integrate molecular endpoints in preclinical study design. Stay updated with emerging trends, technologies, and best practices in molecular biology and qPCR. Qualifications: Ph.D. or Master’s in Molecular Biology, Cell Biology, Biotechnology, or a related field. Minimum 10 years of hands-on experience in molecular biology techniques, with a strong focus on qPCR in in-vitro preclinical models. Excellent analytical, documentation, and communication skills. Desirable Skills: Knowledge of cell-based assay systems, molecular endpoints, and biomarker quantification. Exposure to RT-qPCR, miRNA analysis, or multiplex PCR. Understanding of statistical software or qPCR analysis tools (e.g., SDS, CFX Maestro, Bio-Rad CFX, REST). Engagement Type & Compensation: Consulting basis – Part-time, Remote, Hybrid Remuneration commensurate with experience and scope of involvement.