Specialist - Antibody Discovery

Role : Specialist – Antibody Discovery

Company:

Location:

About the Role

Specialist – Antibody Discovery

What You'll Do

• Program Leadership:

  Lead and manage assigned antibody discovery programs, aligning on plans, milestones, and risk mitigation with the Antibody Discovery Lead.

• Antibody Generation:

  Generate therapeutic, tool-grade, and anti-idiotypic antibodies utilizing platforms such as

  hybridoma, phage/yeast display, and single B-cell screening technologies.

• Cell Line Engineering:

  Drive

  cell engineering

  for recombinant cell lines using state-of-the-art techniques, including

  lentiviral transduction, CRISPR/Cas9, and traditional transfection.

• Reagent and Clone Development:

  Oversee the generation of high-quality reagents (cell lines, recombinant proteins, antibodies) with robust documentation (SOPs/ELN) and quality control. Execute and optimize clone development workflows and screening funnels for mAb/recombinant protein production.

• Upstream Operations:

  Manage upstream activities for large-molecule discovery, covering mammalian cell culture from shake flasks to bench-top bioreactors, ensuring compliance with safety and data integrity standards.

• Team & Project Management:

  Mentor and guide junior scientists/associates. Coordinate effectively with

  Protein Sciences, Analytics, Process Development, and Biology

  to ensure timely program delivery.

• Client Interface:

  Interface with clients (under the Lead’s direction) to present technical updates, manage scope/timelines, and support proposals and Statements of Work (SoWs).

What You'll Bring

Education & Experience:

• PhD

  in Immunology, Molecular Biology, Biotechnology, or a related field.

• Minimum 5+ years of relevant experience

  in antibody discovery and recombinant protein production. (Experience within a

  CRO/CDMO environment is preferred

  ).

Key Skills:

• Deep expertise in multiple

  antibody discovery platforms

  (hybridoma, phage/yeast display, single B-cell).
• Hands-on proficiency in

  cell line engineering

  techniques (lentiviral transduction, CRISPR/Cas9).
• Strong background in

  clone development

  and

  upstream operations

  for biologics.
• Proven abilities in

  team leadership, project execution, and stakeholder/client management.

• Excellent documentation, data analysis, and problem-solving skills.