Scientist I, Protein Biology

Job Description

Work Schedule Standard (Mon-Fri) Environmental Conditions Laboratory Setting, Office About Team: Antibody team The antibody team is involved in engineering and development of antibodies, with a deep focus on reagent quality and specificity. The core activities of the team include design, development, purification, conjugation, and testing of antibodies in a variety of immunoassay applications using groundbreaking tools and technologies. The goal of the program is advanced product development and creation of product-specific information to promote research use. Role: To be an integral part of an antibody development team with a focus on performance and specificity using innovative molecular, protein, biochemical, and cell biology methods. Responsibilities: Meticulous experimental planning and execution to meet program goals. Timely record keeping of results into data sheets and laboratory notebooks. Regular mining of literature and keeping oneself up to date with developments in the field. Compilation and presentation of data in written and oral formats. Active participation in team meetings with attention to detail and adherence to schedules. Strong theoretical and proven understanding of protein and antibody conjugation chemistries. Hands-on experience in performing protein or antibody conjugations to dyes, labels, or reporter tags. Experience with the development of new conjugation protocols and the design of site-specific conjugation strategies is desirable. Experience and knowledge in protein purification and analysis technologies such as affinity or ion exchange chromatography, SEC, HPLC, and SDS-PAGE. Experience or familiarity with antibody or protein engineering, rational design of mutants, and molecular biology. Experience with structural biology and protein modeling and visualization tools such as Pymol, Shrodinger, Discovery Studio or other similar programs is desirable. Theoretical or practical experience in antibody development platforms is desirable. Proficient in MS Office applications such as Word, PowerPoint, Excel, and possess a strong statistical knowledge and familiarity with statistical software such as Prism. Seeking self-motivated candidate who excels in learning and applying new concepts for process or product improvements. Must have strong interpersonal skills to connect with peers and leadership. Show more Show less