Deputy General Manager (DGM) / Assistant General Manager (AGM) – Upstream Production (API)

Key Responsibilities:

Production & Operations Management:

• Manage end-to-end

  upstream processes

  including

  chemical reactions

  ,

  crystallization

  ,

  solvent recovery

  , and

  work-up operations

  .
• Plan and execute daily production activities to meet

  output, quality, and yield

  targets.
• Monitor

  critical process parameters (CPPs)

  and ensure adherence to process design and safety.

Compliance & Documentation:

• Ensure

  GMP compliance

  , and adherence to

  regulatory

  and

  safety guidelines

  (USFDA, EDQM, TGA, WHO).
• Review and approve

  Batch Manufacturing Records (BMRs)

  ,

  SOPs

  ,

  Deviation Reports

  , and

  Change Controls

  related to upstream activities.
• Prepare and support

  regulatory audits

  ,

  customer audits

  , and

  internal inspections

  .

People & Resource Management:

• Lead and develop a team of

  shift engineers, supervisors, and operators

  .
• Schedule manpower, oversee training and ensure adherence to

  SOPs and safety practices

  .
• Foster a culture of

  accountability

  ,

  teamwork

  , and

  continuous improvement

  .

Process & Quality Improvement:

• Collaborate with

  R&D, Technology Transfer, and QA/QC

  teams to ensure smooth

  tech transfer

  and

  scale-up

  of new products.
• Drive

  process optimization

  to improve

  yield, reduce cycle time

  , and

  minimize solvent loss

  .
• Lead

  investigation of deviations, process failures

  , and implement

  corrective actions

  .

Plant & Equipment Oversight:

• Oversee the operation and maintenance of key upstream equipment:

• Reactors (GLR/SSR), condensers, scrubbers, distillation units, receivers

  , etc.
• Coordinate with the Engineering team for

  preventive maintenance

  and

  equipment validation

  .

Inventory & Cost Control:

• Monitor raw material consumption, solvent usage, and utility consumption.
• Drive

  cost-reduction initiatives

  without compromising quality or compliance.

Key Skills and Competencies:

• Deep understanding of

  chemical reaction engineering

  and

  process safety

  .
• Expertise in

  hazardous reaction handling

  , including exothermic and pressure reactions.
• Sound knowledge of

  GMP

  ,

  cGMP

  ,

  ICH

  , and

  regulatory requirements

  .
• Strong leadership, team management, and problem-solving abilities.
• Proficiency in production software (e.g., SAP, DCS, MES) is an added advantage.

Educational Qualifications:

• B.E./B.Tech

  in

  Chemical Engineering

  or equivalent OR

  M.Sc. in Chemistry / Organic Chemistry / Industrial Chemistry

Experience Required:

API manufacturing