Job
Description
Key Responsibilities: Technical & Operational Responsibilities: Lead end-to-end upstream fermentation operations including media preparation, seed culture development, fermentation scale-up , and harvest. Optimize classical microbial fermentation processes for high cell density and metabolite production using bacteria, yeast, or fungi (e.g., E. coli , Bacillus , Saccharomyces , Streptomyces ). Ensure production targets (volume, yield, quality, and timelines) are consistently achieved. Troubleshoot upstream process deviations, contamination, or yield drops. Collaborate with R&D and Tech Transfer teams for scale-up and commercial execution of new strains or processes. Evaluate and implement process improvements , automation, and cost-saving initiatives. Review and ensure accurate documentation (batch records, SOPs, deviation reports, change controls). Compliance & Quality: Ensure operations are in full compliance with cGMP, regulatory, and EHS requirements. Support regulatory audits (USFDA, EMA, WHO, etc.) and customer inspections. Participate in investigations (OOS/OOT, deviations) and implement CAPAs related to upstream activities. Team Leadership & Coordination: Lead, mentor, and develop a team of production officers, operators, and shift engineers. Ensure adequate training of team members on fermentation operations and GMP. Coordinate closely with downstream, QA, maintenance, and warehouse functions for smooth operations. Interested candidates can reach out at jai.mirchandani@symbiotec.in Show more Show less
