Research Scientist/Team Leader – Biocatalysis, Protein purification & Downstream

0 years

0 Lacs

Posted:4 days ago| Platform: Linkedin logo

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Work Mode

On-site

Job Type

Full Time

Job Description

Key Responsibilities:


  • Design and execute experiments for enzyme screening, expression, and purification (affinity, ion exchange, HIC, SEC, etc.).
  • Design studies and lead workstreams for lab‑to‑kilo scale (biotransformations 0.1–20 L; purification mg–10 g and higher)
  • Drive process robustness/scale‑up, troubleshoot enzyme stability/mass transfer/fouling/resin lifetime.
  • Characterize enzymes using biochemical and biophysical techniques (SDS-PAGE, HPLC, LC-MS, UV-Vis, etc.).
  • Collaborate with molecular biology, fermentation, and analytical teams to ensure seamless workflow.
  • Maintain accurate records, analyse data, and present findings in internal meetings.
  • For TL/SRS roles: Lead project teams, coordinate cross-functional activities, and contribute to strategic planning.


What You Bring:


Qualification


Experience:

  • RS: 3–5 yrs. (M.Sc.) or fresh Ph.D.
  • SRS: 5–8 yrs. (M.Sc.) or 2–4 yrs. (Ph.D.)
  • TL: 8–12 yrs. (M.Sc.) or 5–8 yrs. (Ph.D.) with ≥2 yrs. team leadership.
  • Biocatalysis: Enzyme selection/screening, cofactor recycling, immobilization basics, solvent/aqueous systems, pH/DO/mass transfer control, scale‑up, green metrics
  • Purification/ Downstream (from industry): Clarification, precipitation, AKTA/FPLC, chromatography (Affinity/IEX/HIC/SEC), UF/DF/TFF, solvent exchange, crystallization/lyophilization.
  • Analytics/Tools: HPLC/UPLC, GC, LC‑MS, SDS‑PAGE, chiral analytics, DoE (JMP/Minitab), ELN/LIMS, strong Excel/data handling.


Functional Competencies:


Behavioural Competencies:


Interested Candidates are requested to share their resumes on shubhi.chandnani@piind.com

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