Director – Mass Spectrometry Biomarker Discovery (Neuroscience / CNS)(Remote -India)

About the Role

mass spectrometry–based biomarker discovery and validation

Key Responsibilities

Biomarker Assay Development & Validation

• Lead development, optimization, and validation of MS-based biomarker assays for early- and late-phase clinical trials
• Design and oversee targeted and discovery MS workflows for biomarker identification, qualification, and validation
• Implement robust bioanalytical validation procedures to ensure high-performance, reproducible measurements across preclinical and clinical samples

Scientific Leadership & Program Ownership

• Serve as scientific owner for biomarker strategies across neuroscience programs
• Partner with project teams to design and execute in vitro experiments supporting therapeutic characterization
• Provide technical direction, mentorship, and best-practice guidance to junior scientists

Study Design & Cross-Functional Collaboration

• Establish experimental designs and analytical strategies for in-house and outsourced biomarker efforts
• Coordinate method development, sample analysis, and data interpretation with:
• Internal teams (medical, clinical operations, statistics, regulatory)
• External partners (CROs, academic collaborators, specialized laboratories)
• Ensure biomarker approaches align with clinical objectives and regulatory expectations

External Engagement & Scientific Communication

• Act as technical subject-matter expert in CRO and external partner interactions
• Communicate biomarker findings through internal presentations, external publications, and strategic discussions
• Contribute to thought leadership in biomarker innovation and translational science

Required Skills & Experience

• PhD in Neuroscience, Biochemistry, Proteomics, or a related field
• 5+ years of experience in industry, academia, or postdoctoral research with a strong focus on biomarker discovery and development
• Deep technical expertise in:
• LC-MS and LC-MS/MS
• Targeted and/or discovery proteomics
• Proven experience with MS-based assay development, optimization, and clinical validation
• Ability to independently design and execute advanced MS-based studies

Preferred Skills

• Direct experience with CNS or neurodegenerative disease biomarker programs
• CRO oversight or sponsor-side biomarker leadership experience
• Strong cross-functional collaboration with clinical, statistics, and regulatory teams

Employment Details

• Employment Type: Full-time
• Work Mode: Remote from India
• Engagement: Long-term
• Focus: Biomarker discovery, validation, and scientific leadership