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Job Description

  • Jobportal DK
  • Videnskabelige stillinger
Post doc position in cancer genomics

Weischenfeldt research group, BRICUniversity of Copenhagen

We are looking for a highly motivated, creative, and talented PhD-level computational biologist to join our team commencing November 1st, 2025 or as soon as possible hereafter.

Our group and research

The Weischenfeldt lab use genome data science to delineate the mutational mechanisms and clonal evolution of cancer, with a particular focus on genomic structural rearrangements. We use computational and experimental approaches including WGS, single-cell, and long-read sequencing together with chromatin conformation techniques to understand how cancers mutate and evolve, which we are applying to cancer patient material in close collaboration with clinical colleagues at the hospital.

Project Description

Malignant brain tumours are highly complex and heterogeneous disorders, with extensive ongoing clonal evolution. The project involves integrative data science analyses of both retrospective and prospective collected genomic and epigenetic sequencing data, imaging and clinical data from brain tumour patients to examine the evolutionary trajectories and treatment resistance mechanisms of patients with brain tumours.The successful candidates will be joining a larger team of cross-disciplinary cancer researchers and clinicians, with the aims to uncover basic mechanisms that can be translated to the clinic.

Starting date

: November 1st or after agreement.

Duration:

2 years with possibility for extension.

Principal supervisor

is group leader, Prof Joachim Weischenfeldt, BRIC and Rigshospitalet, joachim.weischenfeldt@bric.ku.dk, Phone: +453545 6040

Your job

You will be working with data from patient-derived tumour material in collaboration with other team members. Your job will include development of novel and executing existing computational methods including machine learning methods to integrate genomics, transcriptomics and epigenomics data set to uncover genomic-epigenomic interactions and cancer evolution trajectories. The tasks will include quality assessment, processing and filtering of different data modalities, and co-supervision of junior researchers in the group. You will have the opportunity to develop your own research ideas and approaches. The position involves interdisciplinary research through exchange of ideas and results with clinicians and researchers.

Profile

We are looking for a highly motivated and enthusiastic scientist with the following competencies and experience:

Essential Experience And Skills

  • You have a PhD in computational biology, bioinformatics or related areas
  • You are highly experienced in working with NGS data and have experience with multi-omic data
  • Experience with tumour evolution reconstruction
  • Proficient communication skills and ability to work in teams
  • Excellent English skills written and spoken

Desirable Experience And Skills

  • Experience with machine learning and statistics
  • Knowledge on mutational mechanisms in cancer
  • Publications as co-author or first author in a related area
  • Fellowships, grants and prizes

Place of employment

The place of employment is at BRIC, University of Copenhagen. We offer creative and stimulating working conditions in dynamic and international research environment. Our research facilities include modern laboratories and access to HPC.Please read more about our research at https://www.bric.ku.dk/Research/weischenfeldt-group/

Terms of employment

Salary, pension and terms of employment will be in accordance with the agreement between the Danish Ministry of Finance and AC (Danish Confederation of Professional Associations). Depending on qualifications, a supplement may be negotiated. The employer will pay an additional 18,07 % to your pension fund.Non-Danish and Danish applicants may be eligible for tax reductions, if they hold a PhD degree and have not lived in Denmark the last 10 years.The position is covered by the Job Structure for Academic Staff at Universities 2025.

Questions

For further information please contact Joachim Weischenfeldt, joachim.weischenfeldt@bric.ku.dkForeign applicants may find this link useful: www.ism.ku.dk (International Staff Mobility).

Application procedure

Your Online Application Must Be Submitted In English By Clicking ‘Apply Now’ Below. Furthermore Your Application Must Include The Following Documents/attachments – All In PDF Format
  • Motivated letter of application (max. one page).
  • CV incl. education, work/research experience, language skills and other skills relevant for the position.
  • A certified/signed copy of a) PhD certificate and b) Master of Science certificate. If the PhD is not completed, a written statement from the supervisor will do.
  • List of publications.

Letters of recommendation

Furthermore, the applicant should provide at least one letter of recommendation. To be taken into consideration, the letter must be signed by the supporting person with institutional letter head and in PDF-format. Please make sure that an easy match between the recommendation letter and the individual applicant is possible.

Application deadline:

31. August 2025, 23.59pm CET

We reserve the right not to consider material received after the deadline, and not to consider applications that do not live up to the abovementioned requirements.

The further process

After the expiry of the deadline for applications, the authorized recruitment manager selects applicants for assessment on the advice of the hiring committee. All applicants are then immediately notified whether their application has been passed for assessment by an unbiased assessor. Once the assessment work has been completed each applicant has the opportunity to comment on the part of the assessment that relates to the applicant him/herself.You can read about the recruitment process at https://employment.ku.dk/faculty/recruitment-process/The applicant will be assessed according to the Ministerial Order no. 242 of 13 March 2012 on the Appointment of Academic Staff at Universities.University of Copenhagen wish to reflect the diversity of society and welcome applications from all qualified candidates regardless of age, disability, gender, nationality, race, religion or sexual orientation. Appointment will be based on merit alone.
SØG STILLINGENKøbenhavns Universitet giver sine knap 10.000 medarbejdere muligheder for at udnytte deres talent fuldt ud i et ambitiøst, uformelt miljø. Vi sikrer traditionsrige og moderne rammer om uddannelser og fri forskning på højt internationalt niveau. Vi søger svar og løsninger på fælles problemer og gør ny viden tilgængelig og nyttig for andre.Kontakt

Joachim Lütken Weischenfeldt

E-mail: joachim.weischenfeldt@bric.ku.dkInfo

Ansøgningsfrist:

31-08-2025

Ansættelsesdato:

01-11-2025

Afdeling/Sted:

Biotech Research and Innovation Centre (BRIC)Søg i stillingerSøg

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