Zydus Group logo

Title Biotech (R&D)

2 - 8 years

0 Lacs

ahmedabad gujarat

Posted:21 hours ago| Platform: Shine logo

Apply

Skills Required

hplc uplc mass spectrometry technology transfer stp sop calibration compliance sample management formulation development bmr mfr bpr packaging development artwork development procurement cpp stability studies protocol design diafiltration chromatography quality control facs qpcr agarose gel electrophoresis dna sequencing immunoassays validation analytical methods ttd documentation technology transfer document preparation cmc studies doe studies extractable leachable studies ich studies lentiviral vector manufacturing cell banking mammalian cell lines transfections tangential flow cart manufacturing immune cells handling transducing cells cryopreserving rtpcr cellbased assays qualification

Work Mode

On-site

Job Type

Full Time

Job Description

In this role at ZRC BIOTECH, you will be responsible for various tasks within different groups as outlined below: **Analytical Group:** - Design, perform, and review HPLC\UPLC, structural, and mass spectrometry based experiments. - Develop, qualify analytical methods, and transfer technology. - Prepare STP, SOP, and TTD documentation. - Perform routine calibration of instruments. - Maintain day-to-day compliance of the laboratory. - Manage samples including procurement of materials required for lab activities. **Formulation Development Group:** - Prepare technology transfer documents and collaborate cross-functionally with different teams. - Develop packaging for late phase batches, clinical trial batches, and commercial process validation batches. - Work on art-work development for primary and secondary labeling. - Coordinate with the GDSO team for procurement of equipment and accessories. - Conduct CMC studies for drug product late phase development. - Execute formulation screening studies, stability/degradation studies, and DoE studies. - Manage documentation, stability studies, and protocol design. **Cell and Gene Therapy (CGT) R&D and Manufacturing:** - Qualifications/Experience required: PhD, M. Tech, or M.Sc in Life Sciences, Biochemistry, Biotechnology, or Microbiology. Freshers or candidates with 2-8 years of experience in Cell and Gene Therapy (CGT). - Lentiviral vector manufacturing process development: - Conduct upstream and downstream processes for lentivirus production. - Prepare media and reagents. - Generation of cell banks, reviving, and maintaining mammalian cell lines. - Perform transient and stable transfections for lentivirus generation. - Optimize processes, scale up production, and purify lentivirus. - Record data and prepare regulatory documents. **CAR-T (Chimeric Antigen Receptor T cell) Manufacturing:** - Execute CAR-T cell production at lab scale or with automated/semi-automated systems. - Prepare media and reagents, handle human blood and cells. - Isolate immune cells, transduce cells with lentivirus, and expand cells. - Conduct in-process quality control and release tests. - Perform FACS-based analyses, molecular biology assays, cell-based assays, and immunoassays for potency testing. - Validate/qualify methods and prepare regulatory documents. You should have a background in Life Sciences, Biochemistry, Biotechnology, or Microbiology with either a PhD, M. Tech, or M.Sc degree. Experience in Cell and Gene Therapy (CGT) ranging from freshers to candidates with 2-8 years of experience is preferred for this role.,

More Jobs at Zydus Group

Downstream Purification Scientist role

Ahmedabad, Gujarat, India

Experience: Not specified

|

Salary: Not disclosed

Area Business Manager

Delhi, India

6 - 8 yrs
|

Salary: Not disclosed

Utility Assistant Manager

Anklesvar, Gujarat, India

Experience: Not specified

|

Salary: Not disclosed

Production Manager

Gujarat, India

Experience: Not specified

|

Salary: Not disclosed

Instrumentation Technician

Ahmedabad, Gujarat, India

2.0 - 8.0 yrs
|

Salary: Not disclosed

Mock Interview

Practice Video Interview with JobPe AI

Start Job-Specific Interview
cta

Start Your Job Search Today

Browse through a variety of job opportunities tailored to your skills and preferences. Filter by location, experience, salary, and more to find your perfect fit.

Job Application AI Bot

Job Application AI Bot

Apply to 20+ Portals in one click

Download Now

Download the Mobile App

Instantly access job listings, apply easily, and track applications.

Google Play App Store
coding practice

Enhance Your Skills

Practice coding challenges to boost your skills

Start Practicing Now
Zydus Group logo
Zydus Group

RecommendedJobs for You

Zydus Group logo

Title Biotech (R&D)

Zydus Group

ahmedabad, gujarat