Research and Senior Research Associate - Organic/ADC

Synthesis R&D:

• Responsible to perform routine organic synthesis. (mg to gram scale) & work independently under the guidance of the leader.
• Independently support the scientific team with instrumentation and equipment operation and maintenance.
• Able to understand & interpret various instruments like NMR, Mass, HPLC.
• Instrument purification like Combiflash, big columns, column packing. Deciding the mobile phase for purification.
• Independently handling all types of glassware assembly arrangement, reaction reagent charging, maintaining temperature, nitrogen, etc.
• Should be able to understand the written instruction from the scientist including patents and reprints where procedure highlighted by scientists.
• To train and support the team members.
• Meticulous Documentation & proper data management.
• To maintain the record book of the work done like purification or reaction.
  

ADC (Antibody Drug Conjugate) R&D

• Synthesis and purification of complex antibody drug conjugate (ADC) molecules
• Synthesis of different type of linkers - using natural and un-natural amino acids, PEGs
• Synthesis of high potent drug molecules – payloads
• Purification of complex and large molecules by flash column and HPLC
• Handling various type chemistry with different payloads
• Interpretation and characterization of higher molecular weight compounds
  

• Minimum of 1 year to 4 years of experience working in CRO Industry.
• Strong organizational, project management and problem-solving skills with impeccable multi-tasking abilities.
• Exceptional interpersonal skills.
• Friendly and professional demeanor.
• Ability to write reports and prepare spreadsheets and presentations.
• Excellent organizational skills with an ability to think proactively and prioritize work.
• Proactive, highly motivated with a "can-do" attitude.
• Strong and accurate attention to detail.