24 Api Synthesis Jobs

Greetings!!! We are seeking for a API - Research & Development Synthesis role for a Pharma Manufacturing Company at Chennai . Role & responsibilities: Develop and optimize synthetic routes for APIs and intermediates. Conduct lab-scale experiments and process development for scale-up. Perform literature surveys and impurity profiling. Interpret analytical data (NMR, HPLC, GC, IR) for structural confirmation. Prepare development reports and support tech transfer to kilo/pilot plant. Ensure compliance with GMP, EHS, and regulatory requirements. Collaborate with cross-functional teams (QA/QC, Regulatory, Manufacturing). Maintain accurate documentation for regulatory submissions (DMF, ANDA, etc.). Interested Candidates kindly share your updated cv to srinidhi@bvrpc.com

Develop the scientific & strategic direction of the synthesis research business, overseeing drug discovery initiatives, managing research teams, ensuring the effective administration & growth. Required Candidate profile Ph.D. in Chemistry with 20+ years in CRO/ process development/synthesis with a strong flair of senior/top research leadership role would be an ideal fit. Willing to work at the lab and be a mentor. Perks and benefits Best of CTC, additional perks and benefits

Role & responsibilities Experience in the development of Generic APIs Development / improvement of the assigned products and overall review of development activities. To finalize route based on literature or feasibility of process or availability of raw materials. Technology transfer, scale-up and troubleshooting To provide required relevant information for regulatory filing and response to regulatory queries. To prepare and review documents Maintain the development records and overall review of given projects. To maintain records as per IMS requirements. Preferred candidate profile Must have experience in the development of Generic APIs

Role & responsibilities Expertise in carrying out Multi-step synthesis of organic molecules from milligram to multi-gram scales and their characterization. Responsible for the development efficient synthetic process, which leads to better yields and quality of the product, with less cycle time and cost. Capturing proper learning of the project & would be responsible for maintaining the confidentiality of the project as per the IPR guidelines. Scaling up of process and technology transfer from lab to plant and trouble shooting at the time of scale up. Interpretation of analytical reports like HPLC, GC, NMR, LCMS, IR, GCMS. Knowledge of designing route of synthesis for target molecule. Carried out experiments in laboratory and optimize process in terms of Regulatory Affairs (RA), Safety, cost and time effectiveness. Strong knowledge on process validation in laboratory and demonstration in plants. Adept at preparing documents like Technology transfer document (TTD), Process development report (PDR), presentations and reports for review meetings. Process validation and optimization with QBD. Preparing documents like Solubility chart, Material balance, Green card, Hold time study, Details of process, MSD. Literature search .through Sci-finder and Reaxys Ability to handle linear and parallel multi-step organic synthesis Experienced with purification techniques like thin layer & column chromatography, Crystallization and distillations. Structural elucidation through NMR (1H, 13C), IR, Mass (LC/MS, GC/MS). Good Co ordination with Cross functional teams as well as team mates. Accurate record keeping in laboratory notebook (LNB) and (ELN).

Job description Key Responsibilities: • Conduct organic synthesis experiments to develop and optimize routes for API synthesis. • Design and execute experiments to scale-up synthesis processes from laboratory to pilot plant scale. • Analyze and interpret experimental data to draw conclusions and make recommendations for process improvements. • Collaborate with cross-functional teams including process development, analytical chemistry, and manufacturing to support project objectives. • Maintain accurate records of experimental procedures, observations, and results in accordance with regulatory guidelines. • Stay updated with relevant scientific literature and contribute to the intellectual property portfolio of the company through patent filings and publications. Interested candidates forward resume on anuverma@scllifesciences.com or Whats app/ call on 9988339860.

Role & responsibilities Process Development: Conduct research and design experiments to develop and optimize synthetic routes for API molecules. Perform literature searches for identified API molecules to determine synthesis routes, polymorphs, and analytical methods. Conduct experimental trials to assess feasibility and optimize designed synthetic routes for API molecules. Documentation: Record all experiments in the laboratory notebook (LNB) and maintain corresponding analytical data in organized folders. Design synthetic routes for the synthesis and isolation of impurities and reference standards. Ensure all documentation meets Good Manufacturing Practices (GMP) and regulatory standards. Safety and Compliance: Adhere to all safety protocols and ensure a safe working environment in the laboratory. Develop non-infringing synthetic processes based on literature, raw material availability, and polymorph studies. Stay up-to-date with industry trends, regulatory guidelines, and advancements in chemical synthesis and analytical techniques.Team Collaboration: Plan daily activities for team members, focusing on feasibility studies, process optimization, and laboratory validation. Work closely with the Analytical Research and Development (ARD) team on method development, in-process testing, and reference standards qualification. Qualifications: Education: MSc/BSc in Organic Chemistry, Experience: Minimum of 3-5 years of experience in process development and optimization in the pharmaceutical or bulk drug industry. Skills: Strong knowledge of synthetic organic chemistry and process chemistry. Proficiency in using and interpreting data from analytical instruments. Excellent problem-solving skills and attention to detail. EZective communication and teamwork skills. Ability to work independently and manage multiple projects simultaneously. Preferred candidate profile We are looking for a talented and driven R&D Chemist to join our team. The successful candidate will be responsible for developing and optimizing chemical processes for synthesizing active pharmaceutical ingredients (APIs). This role requires a strong background in synthetic organic chemistry, process development, and scale-up techniques. The R&D Chemist will collaborate with cross-functional teams to ensure the smooth transition of processes from the lab to full-scale production. Perks and benefits

Role & responsibilities Process Development: Conduct research and design experiments to develop and optimize synthetic routes for API molecules. Perform literature searches for identified API molecules to determine synthesis routes, polymorphs, and analytical methods. Conduct experimental trials to assess feasibility and optimize designed synthetic routes for API molecules. Documentation: Record all experiments in the laboratory notebook (LNB) and maintain corresponding analytical data in organized folders. Design synthetic routes for the synthesis and isolation of impurities and reference standards. Ensure all documentation meets Good Manufacturing Practices (GMP) and regulatory standards. Safety and Compliance: Adhere to all safety protocols and ensure a safe working environment in the laboratory. Develop non-infringing synthetic processes based on literature, raw material availability, and polymorph studies. Stay up-to-date with industry trends, regulatory guidelines, and advancements in chemical synthesis and analytical techniques.Team Collaboration: Plan daily activities for team members, focusing on feasibility studies, process optimization, and laboratory validation. Work closely with the Analytical Research and Development (ARD) team on method development, in-process testing, and reference standards qualification. Qualifications: Education: MSc/BSc in Organic Chemistry, Experience: Fresher or 1-2 years experience in process development and optimization in the pharmaceutical or bulk drug industry. Skills: Strong knowledge of synthetic organic chemistry and process chemistry. Proficiency in using and interpreting data from analytical instruments. Excellent problem-solving skills and attention to detail. Effective communication and teamwork skills. Ability to work independently and manage multiple projects simultaneously. Preferred candidate profile We are looking for a talented and driven junior R&D Associate to join our team. The successful candidate will be responsible for developing and optimizing chemical processes for synthesizing active pharmaceutical ingredients (APIs). This role requires a strong background in synthetic organic chemistry, process development, and scale-up techniques. The R&D Chemist will collaborate with cross-functional teams to ensure the smooth transition of processes from the lab to full-scale production. Perks and benefits

Responsibilities: * Develop processes through lab validation * Conduct R&D synthesis with API focus * Collaborate on miscellaneous industry projects * Ensure compliance with safety standards Annual bonus Provident fund Office cab/shuttle

The ideal candidate will be responsible for optimizing API synthesis processes to enhance yield, and quality. Executing experiments to develop novel synthetic routes for APIs, applying principles of organic chemistry and process engineering. Collaboration with cross-functional teams, such as process chemists, analytical chemists, and chemical engineers, will be essential for the development and scale-up of API manufacturing processes. Candidates should possess strong analytical interpretation skills, including proficiency in NMR, MASS, IR, HPLC, and GC techniques. Good communication skills and knowledge of GLP/GMP guidelines are required. Flow chemistry experience is preferred. Preferred candidate profile M.Sc with 3 - 4 Years of experience

Key Responsibilities Conduct synthesis and process development experiments under the guidance of R&D scientists. Health insurance Provident fund

Research Associate Candidate should be experienced in process development in R&D in API synthesis Technology transfer, scale-up and troubleshooting of Lab developed process at Pilot and Commercial level. To carry experimental work for development / improvement of the products assigned. To carry out any job assigned by immediate supervisor / HOD Analytical Associate Well conversant with operating, handling and troubleshooting in HPLC, GC To maintain analytical records as per IMS. Co-ordinate with ADL dept. / Q.C dept. for method development activity. Development or improvement of methods for the assigned project Desired Profile: M.Sc. - Organic Chemistry/Analytical Chemistry Experience: 02 - 07 years Must be having experience in API

Research Associate Candidate should be experienced in process development in R&D in API synthesis Technology transfer, scale-up and troubleshooting of Lab developed process at Pilot and Commercial level. To carry experimental work for development / improvement of the products assigned. To carry out any job assigned by immediate supervisor / HOD Analytical Associate Well conversant with operating, handling and troubleshooting in HPLC, GC To maintain analytical records as per IMS. Co-ordinate with ADL dept. / Q.C dept. for method development activity. Development or improvement of methods for the assigned project Desired Profile: M.Sc. - Organic Chemistry/Analytical Chemistry Experience: 02 - 07 years Must be having experience in API

Walk-In Drive For API Research & Development(R&D)- Venue Details : MSN Laboratories Pvt. Ltd, R&D Centre, Pashamylaram (V), Patancheru (M), Sangareddy (D.t), Telangana on Friday 27-06-2025 . Department : API R&D Designation : Executive / Sr. Executive Experience : 1- 7 Years Qualification : M.Sc. Organic Chemistry Work Location : MSN R&D Center, Pashamylaram, Hyderabad Work Location : MSN R&D Center, Pashamylaram, Hyderabad Interview Venue Details : Venue Details : MSN Laboratories Pvt. Ltd, R&D Centre, Pashamylaram (V), Patancheru (M), Sangareddy (D.t), Telangana on Friday 27-06-2025 .

Develop the scientific & strategic direction of the synthesis research business, overseeing drug discovery initiatives, managing research teams, ensuring the effective administration & growth. Required Candidate profile Ph.D. in Chemistry with 12+ years in CRO/ process development/ chemical synthesis with flair of senior research leadership role would be an ideal fit. Willing to work at the lab and be a mentor. Perks and benefits Best of CTC, additional perks and benefits

Position: Senior Manager - Peptide Production Grade: G9B / G9A Job Location: Ahmednagar Qualification: M.Sc. (Chemistry) / B.E. (Chemical) / B.Tech (Chemical) Experience: 13-18 yrs experience in Peptide API plant Job Profile 1. To plan and execute peptide manufacturing activities as per the schedule and Budget by optimum utilization of plant capacity 2. To ensure the sustainable quality production with optimum utilization of plant capacity. 3. Monitoring and reduction in process TRT, Cleaning TRT, number of preps per batch on Prep HPLC, Improve yields. Improve the process of Synthesis & Analytical Section. 4. Co-ordinate with Purchase, Planning department to deliver the goods in time. 5. To ensure every day interaction with each department for smooth functioning 6. Compliance of waste water disposal as per IN-HOUSE policy 7. To ensure grooming of disciplined workforce and staff to meet the planned growth charts. 8. Developing different innovative practices to increase productivities and up gradation of work culture. 9. To maintain Good Documentation Practices and Good Laboratory Practices 10. Review of batch process record, Standard Operating procedure and cGMP documents 11. Investigation of Deviation, Change Control & OOS 12. Implementation & follow all safety instruction & practices

This opening is at Pune. Role: To develop Polymorphism/Crystallization, particle engineering processes for APIs and scale up to support business deliverables. Title: Senior Manager -/ AGM Solid State Chemistry (R&D Lab) Level: Senior Manager / AGM Qualification: Ph.D. Organic Chemistry full time. PhD: Full time. Part time or correspondence will not be eligible. Experience: 15 years and above in Solid State Chemistry 2-4 Team members will report to this role. This position reports to the Unit Head Working : Alternate Saturday off. Industry: API Pharma R&D. Candidates working in R&D for Formulations are not eligible. Key Responsibilities include: 1. Develop robust, safe and scalable crystallization processes to meet desired polymorphs and solid-state characteristics of APIs wherein process engineering aspects are involved. 2. Develop robust crystallization process for intermediates where there is a challenge in isolating the product 3. Screening and implementation of new technology ( wet milling, dry milling / micronization, Ultrasonic technology, etc.) for problem solving (Crystallization batch /Close loop / Continuous), Filtration, Drying, PS Reduction operations). 4. Understanding the scale dependent / scale independent process parameters though what if studies etc. 5. Cross functional collaboration, working with synthetic chemistry, analytical, and scaleup teams. 6. Having experience in process Scale up, process simulation, PAT tools, Process, development of flow chemistry models, establishment of new and cutting-edge technologies. 7. Ability to scale up APIs ranging from small to complex molecules in an innovative and economic manner.

Roles And Responsibility : Senior Research Chemist in the Process Research Department at Dr. Reddys Institute of Life Sciences, Hyderabad. Develop and execute laboratory experiments to successfully complete customer projects. Conducting feasibility studies, optimizing, and scaling up reactions for the synthesis of APIs, intermediates, and key starting materials. Ensure compliance with regulatory requirement and industry standards. Provide necessary support to plants for product trials, scale up, pilot batches. Provide technical support to tech transfer process and documentation. Continuous process improvement of API Collaborate with cross functional teams, Quality assurance, vendors, sum Ensuring a well-organized and safe laboratory environment while motivating others to uphold the same standards. Employ HPLC, GC, Mass spectrometry and NMR techniques to interpret and characterize product profiles. Perform feasibility studies, risk assessments, and process evaluations to foster continuous improvement and drive innovation. Extensive experience in a wide variety of chemical and dry reactions.

Position: Research Trainee/officer (Organic Chemistry) Experience: 15 Years Education: M.Sc. in Organic Chemistry Key Responsibilities: Carry out the synthesis and purification of organic compounds as per project requirements. Perform routine analytical testing, including NMR, Mass Spectrometry, IR, GC, and HPLC, to evaluate compound structure, purity, and performance. Interpret results from various analytical techniques such as NMR, IR, Mass, GC, and HPLC with strong foundational knowledge in organic chemistry and name reactions. Collaborate with cross-functional teams to improve chemical processes and workflows. Maintain detailed and accurate records of all experiments, observations, and outcomes in laboratory notebooks or digital systems. Participate actively in project meetings, sharing updates and research findings with team members. Stay informed on current trends, tools, and developments in organic chemistry and related fields. Comply with all lab safety protocols and procedures to ensure a safe working environment. Desired Candidate Profile: Solid understanding of organic chemistry concepts and reaction mechanisms. Proficiency in interpreting data from analytical instruments (NMR, IR, Mass, GC, HPLC). Strong analytical thinking, attention to detail, and a proactive attitude toward learning and collaboration. Good communication and documentation skills. Apply Now !! Send your CV to hr2@topioxresearch.com

This opening is at Pune. Role: To develop Polymorphism/Crystallization, particle engineering processes for APIs and scale up to support business deliverables. Title: Manager / Senior Manager - Solid State Chemistry (R&D Lab) Level: Manager / Senior Manager Qualification: Ph.D. Organic Chemistry full time. PhD: Full time. Part time or correspondence will not be eligible. Experience: 11 years and above in Solid State Chemistry 2-4 Team members will report to this role. This position reports to GL. Working : Alternate Saturday off. Industry: API Pharma R&D. Candidates working in R&D for Formulations are not eligible. Key Responsibilities include: 1. Develop robust, safe and scalable crystallization processes to meet desired polymorphs and solid-state characteristics of APIs wherein process engineering aspects are involved. 2. Develop robust crystallization process for intermediates where there is a challenge in isolating the product 3. Screening and implementation of new technology ( wet milling, dry milling / micronization, Ultrasonic technology, etc.) for problem solving (Crystallization batch /Close loop / Continuous), Filtration, Drying, PS Reduction operations). 4. Understanding the scale dependent / scale independent process parameters though what if studies etc. 5. Cross functional collaboration, working with synthetic chemistry, analytical, and scaleup teams. 6. Having experience in process Scale up, process simulation, PAT tools, Process, development of flow chemistry models, establishment of new and cutting-edge technologies. 7. Ability to scale up APIs ranging from small to complex molecules in an innovative and economic manner.

Synthetic experience from Gram to kilogram scale Experience in handling moisture and light sensitive reagents API’s Analysis and characterization of molecule using techniques Structural interpretation of intermediates and finished products

About The Role : Who are you : - You are a fast learner, with an eye for detail, strong problem-solving and debugging skills, and the following - Strong individual contributor who can complete work autonomously with no regular need for review - Capable of running and directing small teams for substantial projects - Driving code reviews, design reviews and architecture discussions - Fully capable of owning and running entire subsystems of work, helping set and maintain professional standards for the entire team - Deep, substantial expertise in multiple programming environments, with a zeal for driving technology & best practices in Engineering - Scaling, Performance, and ensuring High-Availability & Quality of the products - Experiment with new & relevant technologies and tools, and drive adoption - Experience in developing distributed data processing, stream or batch, systems - Design and develop logical and physical data models to meet application requirements. - Coordinate with architects, development team & business analysts; Must have : - 7 to 10 years of experience in back-end development (Designing, developing, testing and deploying large scale applications) - Expertise in Java and Spring Framework - Java 8 or higher. - 3+ years of experience with AWS cloud platform. - Must have experience in leading and managing a team. - Strong organizational and time-management skills. - Excellent oral and written communication skills - Ability to meet communicated deadlines and release project with minimal bugs - Experience in SQL & NoSQL databases (Redis / MongoDB) - Experience in designing and developing high volume web-services using API protocols and data formats - Proficient in API modelling languages and annotation - Exposure to Amazon Web Services (ECS) for release management and (Lambda/S3) for application development. Preferred Qualification : - Bachelors / Master's degree in computer science or related field. Good to have : - Experience building and using ETL systems and integrations. - Exposure to Kafka - Familiarity with front side platforms such Javascript, HTML5, CSS3 and React / Angular / Vue Measures of Success : - Writing quality and bug free code adhering to the functional and non-functional requirements - Follow standard practices (Unit Tests, Reduce technical debt, Code Coverage, Integration Test, etc) - Excellent troubleshooting skills - Memory leaks, GC tuning Apply Insights Follow-up Save this job for future reference Did you find something suspiciousReport Here! Hide This Job Click here to hide this job for you. You can also choose to hide all the jobs from the recruiter.

To assign tasks to staff. To plan the design & development activities and execute accordingly. To prepare respective product dossiers and compile as per CDSCO and WHO requirement. To develop new product as per requirements. Good documentation skills. Good knowledge of RTPCR, ELISA, RDIs etc. Knowledge of CRISPR will be advantage.

Msc in Chemistry, Synthetic R&D, Organic Chemistry, API industry, Process development, Process validation

Sun Pharmaceutical Industries Ltd. Position: Senior Manager API Production (Block Head) Grade: G9B Location: API Ahmednagar - Production Planning and scheduling (day to day basis) - Ensuring resources available (BMR, Raw Material Manpower etc.) Liaison with QC/QA/STORE/Eng. Dept. for solving of trouble shooting problem. - Implementation and monitoring of GMP Standard. - Introduction and scale up of technology transfer. (New Prod 1ct) Constantly monitoring and improvement of product process, efficiency, services etc. - Documentation work, Monthly Report, data preparation (Process trend analysis) and root cause analysis. - Ensure the availability of consumable items & Planning of RM require as per campaign basis. - Ensure the documents related to process I cleaning / House Keeping. Control on fresh as well as recovered solvents/ spent solvent. - Ensure the solid and process waste transfer to respective area and record maintaining. - Other activities entrusted from time to time. Review the prepared/ Revision of BMR and SOP. - Operation of electronic system i.e.ONE HR portal, Metis Track wise, Minitab, Out Look etc. - Ensure Preventive Maintenance of Plant Equipment's in time frame. Ensure the training to subordinates. - Extended Facility of reactor Area of Plant-06 production Planning and scheduling (day to day basis)