Role & responsibilities Experience in operation and trouble shooting of process in plant. Isolation and purification of different organic compound using column chromatographic and crystallization techniques. Optimize the process parameters, what-if studies, holding studies etc. for scale up. Investigation of OOS/OOT and stability related issues. Handled various reagents like NaH, NaBH4, Br2, BHA, n-BuLi,TMSCl, TFA,PPA, Raney Nickel, Pd/carbon & also hazardous chemicals like POCl3, SOCl2 etc. Reactions performed like Hydrogenation,Brominaion,Oxidation,Reduction and condensation. Handling of Moisture sensitive reactions. Study and understand the project requirements, identifying and collection of suitable literature. Support lab manager to prepare weekly technical reports and other project related technical documents (impurity profile tables,Plant batch data,developmental reports) Executing assigned reactions of project. • Looking after the Safety equipments management and maintaining it as per regulatory requirement in R&D lab. • Study the MSDS of each chemical using in every new project and make arrangement of Safety equipments accordingly. Handled HPLC system of Agilent technologies Ezichrome (A.04.07) and version Open Lab cds2.4 • Good in Thin layer chromatography & Column chromatography. Preferred candidate profile Perks and benefits
Roles and Responsibilities Develop new APIs through organic synthesis, method development, and optimization. Conduct literature reviews to stay updated on latest research trends and technologies. Ensure compliance with GMP guidelines during API manufacturing processes. Collaborate with cross-functional teams for product development, scale-up, and commercialization. Perform impurity analysis using techniques like NMR, DSC, etc. Desired Candidate Profile MS/M.Sc(Science) degree in Chemistry or Ph.D/Doctorate in Chemical Sciences from a recognized university. Strong expertise in areas such as API synthesis, organic chemistry, method development/validation/transfer/methodology. 9-14 years of experience in Research & Development (R&D) or related field. Key Responsibilities Literature Review & Route Identification Perform comprehensive literature and patent searches (SciFinder, Reaxys, PubChem, etc.). Identify and evaluate synthetic routes for APIs, intermediates, and impurities. Synthetic Research & Development Plan and perform multi-step organic synthesis experiments. Develop and optimize cost-effective and robust synthetic processes. Work on impurity profiling and synthesis of known/unknown impurities (including nitrosamines/nitroamines). Process Optimization & Scale-Up Support Optimize reaction parameters for higher yield, purity, and reproducibility. Support process development, kilo-lab trials, and technology transfer. Address scale-up challenges in collaboration with process R&D teams. Analytical Collaboration Interpret analytical data (HPLC, LC-MS, NMR, IR) for structure confirmation. Work with Analytical R&D to characterize intermediates, APIs, and impurities. Documentation & Compliance Maintain accurate lab notebooks, experiment records, and reports. Prepare technical documents for DMFs, ANDAs, and regulatory submissions. Ensure GLP, GMP, EHS, and data integrity compliance. Teamwork & Leadership (For Sr. Executive Level) Independently lead assigned projects with minimal supervision. Mentor and guide junior chemists/trainees in lab activities. Provide technical support for regulatory/customer queries.
Roles and Responsibilities Develop new APIs through organic synthesis, method development, and optimization. Conduct literature reviews to stay updated on latest research trends and technologies. Ensure compliance with GMP guidelines during API manufacturing processes. Collaborate with cross-functional teams for product development, scale-up, and commercialization. Perform impurity analysis using techniques like NMR, DSC, etc. Desired Candidate Profile MS/M.Sc(Science) degree in Chemistry or Ph.D/Doctorate in Chemical Sciences from a recognized university. Strong expertise in areas such as API synthesis, organic chemistry, method development/validation/transfer/methodology. 9-14 years of experience in Research & Development (R&D) or related field. Key Responsibilities Literature Review & Route Identification Perform comprehensive literature and patent searches (SciFinder, Reaxys, PubChem, etc.). Identify and evaluate synthetic routes for APIs, intermediates, and impurities. Synthetic Research & Development Plan and perform multi-step organic synthesis experiments. Develop and optimize cost-effective and robust synthetic processes. Work on impurity profiling and synthesis of known/unknown impurities (including nitrosamines/nitroamines). Process Optimization & Scale-Up Support Optimize reaction parameters for higher yield, purity, and reproducibility. Support process development, kilo-lab trials, and technology transfer. Address scale-up challenges in collaboration with process R&D teams. Analytical Collaboration Interpret analytical data (HPLC, LC-MS, NMR, IR) for structure confirmation. Work with Analytical R&D to characterize intermediates, APIs, and impurities. Documentation & Compliance Maintain accurate lab notebooks, experiment records, and reports. Prepare technical documents for DMFs, ANDAs, and regulatory submissions. Ensure GLP, GMP, EHS, and data integrity compliance. Teamwork & Leadership (For Sr. Executive Level) Independently lead assigned projects with minimal supervision. Mentor and guide junior chemists/trainees in lab activities. Provide technical support for regulatory/customer queries.