Research Scientist 1 - DMPK & Bioanalytical

2 - 6 years

0 Lacs

Posted:2 weeks ago| Platform: Shine logo

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On-site

Job Type

Full Time

Job Description

As a candidate for the position, your role will involve performing and analyzing in vitro and in vivo DMPK studies to support drug discovery and development projects. This includes planning, designing, and setting up DMPK experiments, handling instruments, maintaining the laboratory, preparing and reviewing protocols, writing reports, communicating with the project team, and presenting DMPK data in project meetings. Key Responsibilities: - Perform and analyze in vitro and in vivo DMPK studies - Plan, design, and set up DMPK experiments - Handle instruments and maintain the laboratory - Prepare and review protocols - Write reports, communicate with the project team, and present DMPK data in project meetings Required Qualifications: - Ability to set up and perform physiochemical assays such as solubility and logP - Experience in conducting in vitro DMPK assays (microsomal and hepatocyte stability, plasma stability, CYP inhibition, blood/plasma ratio) - Development and validation of bioanalytical methods across various biological matrices - Analysis of in-vivo pharmacokinetic samples - Knowledge of sample processing techniques (protein precipitation, liquid-liquid extraction, solid-phase extraction) - Proficiency in handling LC-MS/MS for quantitative analysis - Protocol preparation, report writing, and presentation of DMPK data in scientific team meetings Additional Details: - Experience in animal handling and conducting pharmacokinetic (PK) studies is beneficial - Working with cell lines such as Caco-2 - Ability to interpret pharmacokinetic data using Phoenix WinNonlin - Experience in a GLP or GLP-like environment Basic Skills Required: - Ability to work independently with enthusiasm and self-motivation - Strong decision-making and problem-solving skills - Effective collaboration and teamwork across multidisciplinary functions - Knowledge of drug discovery and development processes - Excellent oral, written, and interpersonal communication skills with proficiency in English - Proficiency in computer applications including word processing, spreadsheets, and presentation tools Qualifications: - M.Pharm or MS (Pharm) or PhD degree - Industry experience of 2 to 5 years - Candidate must be an Indian citizen - Salary will be commensurate with experience,

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