Research Scientist 1 - DMPK & Bioanalytical

2 - 6 years

0 Lacs

Posted:1 week ago| Platform: Shine logo

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On-site

Job Type

Full Time

Job Description

Role Overview: As a candidate for this position, your key responsibility will be to perform and analyze in vitro and in vivo DMPK studies to support drug discovery and development projects. You will play a crucial role in planning, designing, and setting up DMPK experiments, handling instruments, maintaining the laboratory, and preparing and reviewing protocols. Additionally, you will be in charge of writing reports, communicating with the project team, and presenting DMPK data in project meetings. Key Responsibilities: - Set up and perform physiochemical assays such as solubility and logP - Conduct in vitro DMPK assays including microsomal and hepatocyte stability, plasma stability, CYP inhibition, and blood/plasma ratio - Develop and validate bioanalytical methods across various biological matrices - Analyze in-vivo pharmacokinetic samples - Utilize sample processing techniques like protein precipitation, liquid-liquid extraction, and solid-phase extraction - Proficiently handle LC-MS/MS for quantitative analysis - Prepare protocols, write reports, and present DMPK data in scientific team meetings Qualifications Required: - M.Pharm or MS (Pharm) or PhD degree - 2 to 5 years of industry experience - Must be an Indian citizen Additional Company Details: The company is looking for candidates who have experience in animal handling, conducting pharmacokinetic (PK) studies, working with cell lines such as Caco-2, interpreting pharmacokinetic data using Phoenix WinNonlin, and working in a GLP or GLP-like environment. Basic skills required for this role include the ability to work independently with enthusiasm and self-motivation, strong decision-making and problem-solving skills, effective collaboration and teamwork across multidisciplinary functions, knowledge of drug discovery and development processes, excellent oral, written, and interpersonal communication skills with proficiency in English, and proficiency in computer applications including word processing, spreadsheets, and presentation tools. The salary offered will be commensurate with experience.,

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