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2 - 6 years

8 - 12 Lacs

Posted:3 hours ago| Platform: Naukri logo

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Job Type

Full Time

Job Description

Roles & Responsibilities :

  • Develop, establish, and maintain robust 3D organoid cultures derived from patient tumor samples, with a strong focus on lung, liver, pancreas, or head & neck cancers.
  • Optimize and standardize protocols for generation, expansion, and long-term maintenance of patient-derived organoids to accurately mimic in vivo tumor architecture and microenvironment.
  • Perform advanced characterization of organoids using viability assays, immunofluorescence, confocal microscopy, and molecular profiling techniques (qPCR, RNA-seq, etc.).
  • Design and execute functional assays to assess drug and mRNA-based vaccine responses in organoid models, supporting personalized cancer treatment strategies.
  • Collaborate closely with multidisciplinary teams, including immunologists, molecular biologists, and bioinformaticians, to evaluate immunogenicity and therapeutic efficacy of personalized vaccine candidates.
  • Develop organoid biobanks to enable high-throughput screening and comparative studies across different patient cohorts and cancer types.
  • Maintain meticulous records of all experimental procedures and findings, and contribute actively to internal reports and peer-reviewed publications.
  • Ensure adherence to biosafety, ethical standards, and quality control guidelines throughout organoid culture and experimental workflows.

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