Research Associate/Junior Scientist/Research Scientist - Fungal System

Role & responsibilities

• Responsible for all the projects undertaken in molds (Aspergillus niger, Aspergillus oryzae, Trichoderma spp.) expression systems.
• A strong technical background in strain engineering and manipulating microbes for improved protein expression.
• Excellent hands-on laboratory skill sets in molecular biology to create strategies for the construction of plasmids for over expression of proteins and/or genomic integrations of target genes in molds for obtaining high levels of protein expression.
• Should have in depth understanding of the mold systems to engineer the host for improved production of recombinant protein.
• Strong understanding on the regulation of the protein expression and secretion to develop a regulatory element screening tool kit for over expression of homologous/heterologous proteins.
• Should have basic understanding on the enzyme assays to develop high throughput screening assays for screening the strain libraries to identify the best strain producing the highest amount of functional protein of interest.
• Hands-on experience on Pichia expression system is an added bonus.
• Regulatory Science: Support the regulatory science vertical for method development on production strain safety and product safety as per the regulatory authorities (EFSA, GRAS, etc..)
• Progress reports real time basis, final reports, regulatory dossiers for strain safety or product safety.
• Laboratory responsibilities: General laboratory responsibility.

Preferred candidate profile

• Should demonstrate good technical aptitude and should be able to work independently and in collaboration with cross-team function.
• Should be able to analyse the data and document in real time.

Preferred Qualification

• Ph.D. Fresher/Masters: 4 - 5 years industry or research experience
• Ph.D. in Mold expression system
• M.Sc/M.Tech wth 4 - 5 years of industrial/research experience in handling Mold expression system.