PopVax, an Indian biotechnology company based in Hyderabad, with a primarily remote US subsidiary nominally located in New York, is seeking a senior regulatory executive. The company is funded through research agreements with the Gates Foundation and Vitalik Buterin's biosecurity company, Balvi. Over the past year, PopVax has been developing a novel second-generation mRNA platform for low-cost broadly-protective vaccines using computationally-driven antigen design. The primary focus is on an open-source booster vaccine candidate designed to provide protection against the entire sarbecovirus species and potentially the betacoronavirus genus, including current and future strains of SARS-CoV-2, the virus responsible for COVID-19. Clinical trials for this candidate are planned to commence later this year. The ideal candidate for this role should possess deep expertise in the end-to-end qualification of novel vaccines and biologics in the US, navigating FDA processes from preclinical development to animal trials, GMP manufacturing, human trials (IND), and licensure (BLA). Additionally, experience with regulatory processes in other stringent regimes such as the European Union (EMA), Canada (Health Canada), the UK (MHRA), and Japan (PMDA) is highly desirable. The candidate should be comfortable working independently in a fast-paced environment without immediate support from a regulatory team or junior regulatory executives. Previous experience in regulatory work for a successfully-authorized COVID-19 vaccine in any of these countries would be a significant advantage. The position offers the flexibility to work remotely from any country worldwide (except those sanctioned by the US in ways detrimental to the role). PopVax provides competitive compensation, comprehensive health insurance covering immediate family members (including pre-existing conditions), and a collaborative work environment dedicated to addressing the cutting-edge multidisciplinary challenges associated with the novel mRNA platform.,
As a Manager - IP at PopVax, an Indian biotechnology company based in Hyderabad, your role involves: - Drafting, filing, and prosecuting patent applications across multiple jurisdictions, including India, the US, and Europe - Providing assessments and opinions on patent validity/invalidity, patentability, and freedom-to-operate - Identifying FTO issues proactively and developing risk mitigation strategies - Managing outside counsel work related to patent prosecution and contested proceedings - Conducting patentability, freedom-to-operate, validity/invalidity, & state-of-the art searches, including bio-sequence searches, and preparing search reports - Performing infringement analysis and preparing claim charts and maps - Interacting with multidisciplinary teams involving R&D, Manufacturing, Clinical, and Regulatory, and advising on IP issues Qualifications and Skills required for this position: - A Masters degree in biotechnology or a similar field is required - A patent agent qualification and/or law degree are preferred but not mandatory - 5-8 years of core experience in drafting and prosecution in biotechnology or life sciences domain - Experience handling contested proceedings is preferred, but not mandatory - A good understanding of US and European patent laws - The ability to work well in a team as well as independently pursue tasks and projects when necessary, without close supervision - Complete fluency in English, with excellent oral and written communication skills, and an eye for detail - The ability to work in a highly-demanding and dynamic environment under challenging timelines PopVax is a unique Indian biotechnology company that operates at the forefront of protein design and nucleic acid therapeutics. The team at PopVax, led by industry experts, is focused on developing novel biomedicines to save lives and revolutionize translational biology research. Joining the IP team at PopVax presents an opportunity to work on cutting-edge technology, define IP strategy, and manage a growing patent portfolio in a collaborative and challenging environment. The company offers competitive compensation, comprehensive health insurance, and a collaborative work environment dedicated to solving multidisciplinary challenges in mRNA platform technology.,
PopVax is an Indian full-stack biotechnology company developing novel mRNA vaccines and therapeutics using computational protein design. Our first vaccine is a next-generation COVID-19 booster which will enter a first-in-human Phase I clinical trial in the U.S. early next year this vaccine is intended to broaden protection against both current and predicted future SARS-CoV-2 variants, reducing the possibility of a new mutation in the virus suddenly causing another massive wave of infection. We have a preclinical pipeline of 6 additional novel vaccine candidates built on our mRNA-LNP platform that we will be taking into clinical trials over the next few years. Our work to date has been funded primarily via project agreements totalling 10+ million USD with the Bill & Melinda Gates Foundation and Vitalik Buterin's public health & biosecurity organization Balvi. We are seeking an Applied Statistician to join our team in Hyderabad (note: in-person only, we do not offer remote work) to play a key role across our programs. Responsibilities will include: Collating and processing diverse, unstructured biological and chemical data produced by PopVax's scientific teams on a daily basis Performing basic statistical analyses such as t-tests, ANOVA, Pearson and Spearman correlations, and generating brief markdown reports Producing data visualisations to fit specific requests Liaising with PopVax's scientific teams to improve and optimize data reporting methods and formats The Ideal Candidate Will Have Thorough theoretical understanding of Probability and Statistics A degree in Statistics, Data Science, Applied Mathematics or a similar quantitative field Excellent proficiency with R or Python Familiarity using R packages such as dplyr, ggplot2 and shiny or Python packages such as pandas, scipy, matplotlib, seaborn and plotly At least 2 years of experience with data processing and visualisation A demonstrated ability to produce clean data reports and visualisations especially using markdown-based tools like Rmd and Quarto A willingness to handle relatively large volumes of unstructured and poorly annotated data, working quickly on often-tight deadlines Basic understanding of machine learning techniques such as regression, decision trees, clustering and dimensionality reduction We offer very competitive compensation, comprehensive health insurance covering immediate family (including pre-existing conditions), and, most importantly, a collaborative work environment focused on solving the cutting-edge multidisciplinary challenges of our novel mRNA platform.
As a computational protein designer at PopVax, you will play a crucial role in utilizing various protein design and engineering techniques to contribute to the development of novel mRNA vaccines and therapeutics. Your responsibilities will include: - Utilizing protein design techniques such as brute force mutation, molecular dynamics simulations, ML-based approaches like constrained hallucination, in-painting, and diffusion, and protein language models for sequence optimization. - Collaborating with software engineers and machine learning scientists to enhance productivity. - Contributing to the open culture of publication for methods and encouraging independent research agendas alongside company goals. To qualify for this role, you should possess the following qualifications: - Experience in using computational tools to design or engineer proteins. - Familiarity with state-of-the-art machine learning methods. - Proficiency in writing code to develop and train models. PopVax, an Indian full-stack biotechnology company, is focused on developing broadly-protective vaccines against pandemic potential pathogens. The company has received funding from the Bill & Melinda Gates Foundation and Balvi for its projects. Remote work options are available for highly qualified candidates, with periodic site visits to the Hyderabad lab. Academic partnerships and part-time appointments can also be negotiated for candidates wishing to maintain ties with academia. If you believe you have the requisite background knowledge and skills to contribute to PopVax's mission of ensuring global access to innovative medical solutions, we encourage you to apply and elaborate on your relevant experience in the application. Join us at PopVax and be a part of the team working towards developing next-generation vaccines for broader protection against infectious diseases.,
PopVax is an Indian full-stack biotechnology company developing novel mRNA vaccines and therapeutics using computational protein design. Our first vaccine is a next-generation COVID-19 booster, which will enter a first-in-human Phase I clinical trial in the U.S. early this year. This vaccine is intended to broaden protection against both current and predicted future SARS-CoV-2 variants, reducing the possibility of a new mutation in the virus suddenly causing another massive wave of infection. We have a preclinical pipeline of 6 additional novel vaccine candidates built on our mRNA-LNP platform that we will be taking into clinical trials over the next few years. Our work to date has been funded primarily via project agreements totalling 10+ million USD with the Bill & Melinda Gates Foundation and Vitalik Buterin's public health & biosecurity organisation Balvi. We have built and operationalized a small-scale GMP-capable mRNA foundry in Hyderabad to produce clinical doses for this trial, as well as others in our pipeline. We are looking to hire a new member for our Process Development & Manufacturing team to help adapt and scale up cutting-edge technologies from the lab to the rigors of a cGMP-compliant production process. The ideal candidate will have a strong scientific background, preferably in a field such as molecular biology or nanoparticle formulation, as well as a solid understanding of GMP regulations and documentation. They should be comfortable working on the bench, either in the R&D lab or in the production facility, as needed. Role Responsibilities Work closely with R&D teams to adapt lab-scale protocols that underpin key production process steps across molecular biology, nanoparticle formulation, chromatography, and other related fields into SOPs for GMP-compliant dose production. Help plan and participate directly in all aspects of manufacturing operations, including upstream processes, downstream processes, formulation, filling, packaging, and labeling, as well as the execution of process validation for these processes. Participate in and perform fermentation of bacterial cultures, particularly E. coli, from flask level to mid-scale dedicated bioreactors and fermenters, including biomass separation and other upstream activities. Participate in and perform mRNA IVT and nanoparticle formulation. Participate in and perform purification processes, including chromatography using FPLC (AKTA-like systems), tangential flow filtration (TFF), and terminal filtration. Ensure that all manufacturing activities comply with regulatory requirements, including Schedule M (Indian), ICH, US FDA cGMP, and other relevant standards. Implement and maintain quality systems and procedures to ensure product quality and safety. Continuously assess manufacturing processes to identify areas for improvement. Develop and implement strategies to increase efficiency, reduce waste, and improve product quality. Implement best practices and benchmark performance against industry standards. Participate directly in the maintenance and calibration of manufacturing equipment. Coordinate with maintenance and engineering teams to ensure that equipment operates effectively and that facilities meet regulatory standards. Set up formula-enabled spreadsheets to represent comprehensive bills of materials (BOMs) for manufacturing processes, ensuring they can be rapidly adapted to any changes in manufacturing materials and techniques. Manage inventory levels of raw materials, components, and finished products. Coordinate with procurement and supply chain teams to ensure adequate inventory levels while minimizing excess inventory and waste. Promote a culture of safety and compliance within the manufacturing facility. Ensure that all employees follow safety protocols and use appropriate personal protective equipment (PPE). Conduct regular safety inspections and audits to identify and mitigate potential hazards. Collaborate with other departments, including Quality Assurance, Regulatory Affairs, Research and Development, and Supply Chain, to support product development, regulatory submissions, and overall business objectives. Write and execute validation protocols for equipment, processes, and procedures according to QA requirements. Generate validation reports, investigation reports, root cause analyses, and conclusions. The Ideal Candidate Will Possess A master's degree in a pharmaceutical, biology, biotechnology, or other life sciences field. A strong scientific background in one or more of molecular biology, nanoparticle formulation, and organic chemistry. Strong applied mathematical skills, including basic statistical analysis. 5+ years of production experience in a cGMP environment, with hands-on experience directly participating in production activities on the shop floor. Vaccines or other biologics experience is preferred, and specific experience with nucleic acid or nanoparticle-based products would be a significant advantage. A deep understanding of cGMP requirements and regulations, as well as the core principles underlying them, and experience drafting GMP SOPs, BMRs, production reports, and other related documents. A strong grasp of QMS principles, with direct experience handling and documenting deviations, change control, CAPA, OOS, and OOT investigations.
PopVax is an Indian full-stack biotechnology company developing novel mRNA vaccines and therapeutics using computational protein design. Our first vaccine is a next-generation COVID-19 booster, which will enter a first-in-human Phase I clinical trial in the U.S. this year. We have a preclinical pipeline of 6 additional novel vaccine candidates built on our mRNA-LNP platform that we will be taking into clinical trials over the next few years. Our work to date has been funded primarily via project agreements totalling 10+ million USD with the Bill & Melinda Gates Foundation and Vitalik Buterin's public health & biosecurity organisation Balvi. We are looking for an exceptional Scientist for our Hyderabad labs to design, develop, and validate immunoassays (including flow cytometry-based T-cell assays, and other cell-based functional assays) to evaluate immune responses and cytotoxicity. You will also analyse, interpret, and document experimental results while collaborating with cross-functional teams. Qualifications A PhD or Master’s degree in Cancer Biology, Cell Biology, Immunology or Biotechnology is a requirement, with 3+ years of relevant industry experience is strongly preferred. Demonstrated experience in bioassay development and extensive hands-on experience with flow cytometry, and cell-based functional assays is must. Proficiency in data analysis using software such as GraphPad Prism and FlowJo will be useful. At least six months experience performing mammalian cell culture (both adherent and suspension cell lines). Previous experience of working with primary immune cells, spheroid/organoid models and peripheral blood mononuclear cells will be an advantage. Excellent verbal and written communication skills. The ability to present scientific findings clearly and concisely is a vital and non-negotiable component of success at PopVax. Strong analytical and problem-solving abilities, with a demonstrated track record of independently interpreting experimental data and troubleshooting technical challenges. A willingness to shoulder substantial and often repetitive assay workloads on a daily basis and a desire to rapidly learn, troubleshoot, and master new experimental techniques. Able to maximise his/her contribution in the assigned projects with proper planning and execution is necessary. Strictly adhering to good lab practices, maintaining laboratory records and ensuring compliance with company policies, safety regulations, and quality standards at all times in the office premises is mandatory. We offer very competitive compensation, comprehensive health insurance with the option to cover immediate family (including pre-existing conditions), and, most importantly, a collaborative work environment focused on solving the cutting-edge multidisciplinary challenges of our novel mRNA platform.
PopVax is an Indian full-stack biotechnology company developing novel mRNA vaccines and therapeutics using computational protein design. Our first vaccine is a next-generation COVID-19 booster, which will enter a first-in-human Phase I clinical trial in the U.S. this year. We have a preclinical pipeline of 6 additional novel vaccine candidates built on our mRNA-LNP platform that we will be taking into clinical trials over the next few years. Our work to date has been funded primarily via project agreements totalling 10+ million USD with the Bill & Melinda Gates Foundation and Vitalik Buterin's public health & biosecurity organisation Balvi. We are looking for a highly motivated Junior Scientist for our Hyderabad labs who will be responsible for a range of essential laboratory activities, including the routine performance of various immunoassays such as ELISA and Pseudovirus Neutralization Titer (PVNT) assays. A significant portion of this role will also involve the routine execution of cell culture activities, including cell line maintenance, propagation, and preparation for experimental procedures. Furthermore, you will be actively involved in transfection experiments and Pseudovirus (PSV) generation, contributing directly to the development and characterisation of viral systems. You will also provide vital support for other cell culture-based assays integral to the HCV project. Qualifications For MSc/MTech Candidates: A Master's degree (MSc or MTech) in Immunology, Life Sciences, Biotechnology or Virology, with 0–2 years of relevant experience in the following: Hands-on experience with various immunoassays, including ELISA and PVNT assay. This includes a solid understanding of assay principles, troubleshooting, and data interpretation to ensure accuracy and reliability. Practical experience with mammalian cell culture techniques, including aseptic handling, media preparation, cell passaging, cryopreservation, and cell line maintenance. Hands-on experience with transfection protocols for introducing genetic material into cells and the generation of Pseudovirus (PSV) for use in neutralization assays. Excellent verbal and written communication skills. The ability to present scientific findings clearly and concisely is a vital and non-negotiable component of success at PopVax. Strong analytical and problem-solving abilities, with a demonstrated track record of independently interpreting experimental data and troubleshooting technical challenges. A willingness to shoulder substantial and often repetitive assay workloads on a daily basis and a desire to rapidly learn, troubleshoot, and master new experimental techniques. Able to maximise his/her contribution in the assigned projects with proper planning and execution is necessary. Strictly adhering to good lab practices, maintaining laboratory records and ensuring compliance with company policies, safety regulations, and quality standards at all times in the office premises is mandatory. We offer very competitive compensation, comprehensive health insurance with the option to cover immediate family (including pre-existing conditions), and, most importantly, a collaborative work environment focused on solving the cutting-edge multidisciplinary challenges of our novel mRNA platform.
PopVax is an Indian full-stack biotechnology company developing novel mRNA vaccines and therapeutics using computational protein design. Our first vaccine is a next-generation COVID-19 booster, which will enter a first-in-human Phase I clinical trial in the U.S. this year. We have a preclinical pipeline of 6 additional novel vaccine candidates built on our mRNA-LNP platform that we will be taking into clinical trials over the next few years. Our work to date has been funded primarily via project agreements totalling 10+ million USD with the Bill & Melinda Gates Foundation and Vitalik Buterin's public health & biosecurity organisation Balvi. We are looking for an exceptional Scientist for our Hyderabad labs who will be responsible for executing molecular biology workflows for gene expression, protein production, and assay development for various programs. The role demands strong expertise in recombinant DNA technology, experimental design, and troubleshooting, as well as the ability to independently plan and execute projects in a collaborative research environment. Qualifications A PhD in Biochemistry, Biotechnology, or Molecular Biology, or M.Sc. with 5–7 years of relevant industrial experience in Molecular Biology & protein expression. Demonstrable experience in performing DNA, RNA, and protein extraction, purification, and quantification using established and advanced molecular biology methods. Experienced in designing and conducting PCR, qRT-PCR, and cloning workflows using restriction enzyme–based, Gibson Assembly, Gateway, Golden Gate, and In-Fusion techniques. Has built vectors from scratch in silico, using molecular design software for sequence optimisation and construct validation. Has expressed recombinant proteins in bacterial, yeast, insect, and mammalian cells, including both transient and stable transfection systems. Carried out biochemical and molecular assays, including ELISA and nucleic acid/protein quantification using spectroscopic and fluorometric methods. Performed protein–protein interaction studies (e.g., pull-downs, co-IP, affinity purification) and support assay development for new molecular platforms. Participated in high-throughput cloning, screening, and expression studies to evaluate construct performance and optimise conditions. Excellent verbal and written communication skills. The ability to present scientific findings clearly and concisely is a vital and non-negotiable component of success at PopVax. A willingness to shoulder substantial and often repetitive assay workloads on a daily basis and a desire to rapidly learn, troubleshoot, and master new experimental techniques. Able to maximise his/her contribution in the assigned projects with proper planning and execution is necessary. Strictly adhering to good lab practices, maintaining laboratory records and ensuring compliance with company policies, safety regulations, quality standards and data traceability in accordance with GLP/GMP documentation at all times is mandatory. We offer very competitive compensation, comprehensive health insurance with the option to cover immediate family (including pre-existing conditions), and, most importantly, a collaborative work environment focused on solving the cutting-edge multidisciplinary challenges of our novel mRNA platform.
PopVax is an Indian full-stack biotechnology company developing novel mRNA vaccines and therapeutics using computational protein design. Our first vaccine is a next-generation COVID-19 booster, which will enter a first-in-human Phase I clinical trial in the U.S. in 2026. We have a preclinical pipeline of 6 additional novel vaccine candidates built on our mRNA-LNP platform that we will be taking into clinical trials over the next few years. PopVax has recently spun up cancer immunotherapy programs for HCC (Liver Cancer), PDAC (Pancreatic Cancer) & other critical targets. Our work to date has been funded primarily via project agreements totalling 20+ million USD with the Bill & Melinda Gates Foundation, Vitalik Buterin's public health & biosecurity organisation Balvi, BARDA (Biomedical Advanced Research & Development Authority) & Renaissance Philanthropy. We are seeking an exceptional Scientist for our Hyderabad labs who will perform crucial experimental work related to ongoing Mycobacterium tuberculosis (mTB) and Group A Streptococcus (GAS) projects. This will involve in-depth investigations into understanding immune responses, and evaluating vaccine efficacy. The ideal candidate will possess a strong background in microbiology & immunology, with a proven track record in laboratory research. They should be capable of working independently and collaboratively within a fast-paced research environment, contributing significantly to our mission of developing effective vaccines against these critical pathogens. Qualifications For MSc/MTech Candidates: A Master's degree (MSc or MTech) in Microbiology, Life Sciences, or Biotechnology, coupled with 1-3 years of demonstrable relevant experience in the areas outlined above. For Ph.D. Candidates: A Ph.D. degree in Microbiology, Life Sciences, or Biotechnology, with relevant experience as described. The Ph.D. experience should reflect a strong research background and the ability to design and execute independent research projects. Prior hands-on experience working with Group A Streptococcus (GAS) bacteria and Mycobacterium tuberculosis (mTB) is highly preferred. This includes knowledge of their growth characteristics, handling precautions, and relevant experimental methodologies. Demonstrate robust analytical skills to critically evaluate experimental outcomes, identify trends, and draw sound conclusions. Excellent verbal and written communication skills. The ability to present scientific findings clearly and concisely is a vital and non-negotiable component of success at PopVax. A willingness to shoulder substantial and often repetitive assay workloads on a daily basis and a desire to rapidly learn, troubleshoot, and master new experimental techniques. Able to maximize his/her contribution in the assigned projects with proper planning and execution is necessary. Strictly adhering to good lab practices, maintaining laboratory records and ensuring compliance with company policies, safety regulations, and quality standards at all times in the office premises is mandatory. We offer very competitive compensation, comprehensive health insurance with the option to cover immediate family (including pre-existing conditions), and, most importantly, a collaborative work environment focused on solving the cutting-edge multidisciplinary challenges of our novel mRNA platform.
As a Scientist at PopVax, an Indian full-stack biotechnology company specializing in developing mRNA vaccines and therapeutics, your role will involve designing, developing, and validating immunoassays to evaluate immune responses and cytotoxicity. This includes utilizing flow cytometry-based T-cell assays and other cell-based functional assays. Additionally, you will be responsible for analyzing, interpreting, and documenting experimental results while collaborating with cross-functional teams. Key Responsibilities: - Design, develop, and validate immunoassays, including flow cytometry-based T-cell assays and other cell-based functional assays. - Analyze, interpret, and document experimental results. - Collaborate with cross-functional teams to ensure the success of projects. Qualifications: - A PhD or Masters degree in Cancer Biology, Cell Biology, Immunology, or Biotechnology is required, with 3+ years of relevant industry experience preferred. - Demonstrated experience in bioassay development and extensive hands-on experience with flow cytometry and cell-based functional assays is a must. - Proficiency in data analysis using software such as GraphPad Prism and FlowJo will be beneficial. - At least six months of experience performing mammalian cell culture (both adherent and suspension cell lines). - Previous experience working with primary immune cells, spheroid/organoid models, and peripheral blood mononuclear cells is advantageous. - Excellent verbal and written communication skills are essential for presenting scientific findings clearly and concisely. - Strong analytical and problem-solving abilities, with a track record of independently interpreting experimental data and troubleshooting technical challenges. - Willingness to handle significant and often repetitive assay workloads daily and a desire to learn and master new experimental techniques. - Ability to maximize your contribution in assigned projects through proper planning and execution. - Strict adherence to good lab practices, maintaining laboratory records, and ensuring compliance with company policies, safety regulations, and quality standards at all times in the office premises. At PopVax, we offer competitive compensation, comprehensive health insurance with coverage for immediate family members (including pre-existing conditions), and a collaborative work environment focused on addressing the cutting-edge multidisciplinary challenges of our novel mRNA platform.,
As a Scientist at PopVax, an Indian full-stack biotechnology company, your role will involve executing molecular biology workflows for gene expression, protein production, and assay development for various programs. You are expected to have strong expertise in recombinant DNA technology, experimental design, and troubleshooting. Moreover, you should possess the ability to independently plan and execute projects in a collaborative research environment. Key Responsibilities: - Perform DNA, RNA, and protein extraction, purification, and quantification using established and advanced molecular biology methods. - Design and conduct PCR, qRT-PCR, and cloning workflows using techniques such as restriction enzyme-based, Gibson Assembly, Gateway, Golden Gate, and In-Fusion. - Build vectors from scratch in silico, utilizing molecular design software for sequence optimization and construct validation. - Express recombinant proteins in bacterial, yeast, insect, and mammalian cells, including both transient and stable transfection systems. - Conduct biochemical and molecular assays, including ELISA and nucleic acid/protein quantification using spectroscopic and fluorometric methods. - Perform protein-protein interaction studies (e.g., pull-downs, co-IP, affinity purification) and support assay development for new molecular platforms. - Participate in high-throughput cloning, screening, and expression studies to evaluate construct performance and optimize conditions. Qualifications: - PhD in Biochemistry, Biotechnology, or Molecular Biology, or M.Sc. with 5-7 years of relevant industrial experience in Molecular Biology & protein expression. - Demonstrable experience in molecular biology methods including DNA, RNA, and protein extraction, purification, and quantification. - Experience in PCR, qRT-PCR, and cloning workflows using various techniques. - Proficiency in building vectors from scratch in silico and expressing recombinant proteins in different cell types. - Ability to conduct biochemical and molecular assays, as well as protein-protein interaction studies. - Excellent verbal and written communication skills for presenting scientific findings clearly and concisely. - Willingness to handle substantial assay workloads, troubleshoot, and master new experimental techniques. - Strong planning and execution skills to maximize contribution to assigned projects. - Adherence to good lab practices, maintenance of laboratory records, and compliance with quality standards and regulations. At PopVax, you will benefit from competitive compensation, comprehensive health insurance, and a collaborative work environment focused on addressing the cutting-edge challenges of the novel mRNA platform.,
PopVax is an Indian full-stack biotechnology company developing novel mRNA vaccines and therapeutics using computational protein design. Our first vaccine is a next-generation COVID-19 booster, which will enter a first-in-human Phase I clinical trial in the U.S. next year. We have a preclinical pipeline of 6 additional novel vaccine candidates built on our mRNA-LNP platform that we will be taking into clinical trials over the next few years. Our work to date has been funded primarily via project agreements totalling 10+ million USD with the Bill & Melinda Gates Foundation and Vitalik Buterin's public health & biosecurity organization Balvi. We seek a creative, detail-oriented, scientifically grounded Senior Patent Associate to help translate our cutting-edge research into developing strong patent assets and support product development mindful of the evolving patent landscape. This is a unique opportunity to join our IP team in Hyderabad to contribute to and execute our patent strategies. The work will be intellectually challenging, and the hours may sometimes be long, but there will not be a moment of boredom. Primary Responsibilities Will Include Conducting patentability, freedom-to-operate, validity/invalidity, & state-of-the-art searches, including bio-sequence searches, on paid and free databases, and preparing search reports Identifying and preparing literature reviews, technological trends, and competitive intelligence reports Performing infringement analysis and preparing claim charts and maps Identifying FTO issues proactively Providing support in drafting and prosecuting patent applications Interacting with multidisciplinary teams involving R&D, Manufacturing, Clinical and Regulatory, and providing IP support The ideal candidate will possess the following qualifications and skills : A Master’s degree in biotechnology or a similar field is required. 2-4 years of core experience in searching in the biotechnology domain, including bio-sequence searching, is required. Experience in drafting and prosecuting patent applications is desirable but not mandatory. A good understanding of US and European patent laws and the regulatory environment Strong analytical skills to rapidly review and evaluate technical information to gather actionable insights with attention to detail The ability to work well in a team as well as independently pursue tasks and projects, when necessary, without close supervision Complete fluency in English, with excellent oral and written communication skills, and an eye for detail The ability to work in a highly demanding and dynamic environment under challenging timelines We nurture a collaborative work environment focused on solving the cutting-edge multidisciplinary challenges of our novel mRNA platform and, more importantly, provide a platform to work at the frontiers of multiple therapeutic areas. And we offer competitive compensation and comprehensive health insurance covering immediate family (including pre-existing conditions).
PopVax is an Indian full-stack biotechnology company developing novel mRNA vaccines and therapeutics using computational protein design. Our first vaccine is a next-generation COVID-19 booster, which will enter a first-in-human Phase I clinical trial in the U.S. next year. We have a preclinical pipeline of 6 additional novel vaccine candidates built on our mRNA-LNP platform that we will be taking into clinical trials over the next few years. Our work to date has been funded primarily via project agreements totalling 10+ million USD with the Bill & Melinda Gates Foundation and Vitalik Buterin's public health & biosecurity organization Balvi. We seek a creative, detail-oriented, scientifically grounded Senior Patent Associate to help translate our cutting-edge research into developing strong patent assets and support product development mindful of the evolving patent landscape. This is a unique opportunity to join our IP team in Hyderabad to contribute to and execute our patent strategies. The work will be intellectually challenging, and the hours may sometimes be long, but there will not be a moment of boredom. Primary Responsibilities Will Include Conducting patentability, freedom-to-operate, validity/invalidity, & state-of-the-art searches, including bio-sequence searches, on paid and free databases, and preparing search reports Identifying and preparing literature reviews, technological trends, and competitive intelligence reports Performing infringement analysis and preparing claim charts and maps Identifying FTO issues proactively Providing support in drafting and prosecuting patent applications Interacting with multidisciplinary teams involving R&D, Manufacturing, Clinical and Regulatory, and providing IP support The ideal candidate will possess the following qualifications and skills : A Master's degree in biotechnology or a similar field is required. 2-4 years of core experience in searching in the biotechnology domain, including bio-sequence searching, is required. Experience in drafting and prosecuting patent applications is desirable but not mandatory. A good understanding of US and European patent laws and the regulatory environment Strong analytical skills to rapidly review and evaluate technical information to gather actionable insights with attention to detail The ability to work well in a team as well as independently pursue tasks and projects, when necessary, without close supervision Complete fluency in English, with excellent oral and written communication skills, and an eye for detail The ability to work in a highly demanding and dynamic environment under challenging timelines We nurture a collaborative work environment focused on solving the cutting-edge multidisciplinary challenges of our novel mRNA platform and, more importantly, provide a platform to work at the frontiers of multiple therapeutic areas. And we offer competitive compensation and comprehensive health insurance covering immediate family (including pre-existing conditions).
PopVax is an Indian full-stack biotech building first-in-class and best-in-class vaccines and cancer immunotherapies using machine learning-driven design and relentless empiricism. We design, develop, and manufacture our own RNA medicines end-to-end because we believe great pharmaceutical science can only flourish in tight feedback loops that iterate rapidly. PopVax's experimental work and clinical dose production is based at the RNA Foundry, our integrated R&D and GMP-capable clinical dose production facility in Hyderabad. PopVax's north star is our goal of developing novel vaccines and therapeutics over the next decade with the cumulative ability to save 1 million lives each year the Million Lives Mission. To that end, we are developing first-in-class vaccines against Hepatitis C Virus, Strep A, and adult pulmonary TB, broadly-protective best-in-class vaccines against COVID-19, influenza, and HPV, and precision immunotherapies against hard-to-treat solid tumours such as liver cancer and pancreatic cancer. Our work is funded by Vitalik Buterin's Balvi Fund, the Gates Foundation, the US Biomedical Advanced Research and Development Authority (BARDA), and Renaissance Philanthropy. Our first vaccine program will begin a Phase I clinical trial in the US in mid-2026 conducted & sponsored by the National Institutes of Health (NIH). We intend to put 6 novel vaccines and immunotherapies into Phase I clinical trials over the next 3 years. No matter the job title, each person's role at PopVax is ultimately focused on helping take safe & effective new medicines that represent a step-change improvement on the current standard-of-care to the people who need them as fast as possible. If you want to work where the ambition is high, the learning curve is steep, and the work matters to billions, you'll feel at home here. If you're excited by the idea of advancing scientific, clinical, and regulatory frontiers of vaccines and immunotherapies, spending each day developing medicines with the potential to save millions of lives, and building a generational global pharmaceutical company in India along the way join us! We are seeking a Warehouse Manager who will run all warehouse operations in a sterile manufacturing setup, ensuring materials move with speed, precision, and complete GMP compliance. This is a role for someone who can think in systems, execute without fail, and keep operations audit-ready at all times. Key Responsibilities Supervise and control end-to-end warehouse operations for GMP manufacturing & R&D teams. Maintain accurate inventory using FEFO principles and ensure real-time documentation as per cGMP norms. Oversee receipt, quarantine, sampling, release, storage, and issuance of raw materials, consumables, and components. Ensure environmental controls, cleanliness, and segregation within the warehouse. Coordinate closely with QA, QC, Production, R&D and Procurement to ensure uninterrupted material flow. Lead material traceability, batch reconciliation, and support investigations. Prepare and maintain SOPs, logs, labels, and electronic records. Drive regulatory compliance and face internal/external audits with complete confidence. Implement continuous improvements in warehouse layout, safety, and process efficiency. Supervise warehouse staff and ensure adherence to training, discipline, and GMP expectations. Qualifications Bachelor's degree in Science, Pharmacy, Engineering, or related discipline. 48+ years experience in GMP warehouse operations (pharma, vaccines, biologics, or similar). Strong understanding of cGMP, GDP, FEFO, batch traceability, documentation practices, and audit preparedness. Experience with ERP/Inventory Management Systems. Ability to lead teams and coordinate across functions in a fast-paced environment. We offer very competitive compensation, comprehensive health insurance covering immediate family (including pre-existing conditions), and, most importantly, a collaborative work environment focused on solving the cutting-edge multidisciplinary challenges of our novel mRNA platform.
As a senior regulatory executive at PopVax, your role will involve overseeing the end-to-end qualification of novel vaccines and biologics in the US through FDA processes. This includes managing the entire process from preclinical development to animal trials, GMP manufacturing, human trials (IND), and licensure (BLA). Your expertise in navigating the regulatory landscape will be crucial in ensuring successful approval and market entry for our innovative medicines. Key Responsibilities: - Lead the regulatory strategy and submission process for novel vaccines and biologics in the US, ensuring compliance with FDA requirements at every stage of development. - Collaborate with cross-functional teams to provide regulatory guidance and support, driving alignment on regulatory milestones and objectives. - Monitor and interpret regulatory developments, guidelines, and policies to inform decision-making and mitigate risks. - Interface with regulatory agencies, including the FDA, to facilitate communication and address any inquiries or requests for additional information. - Maintain up-to-date knowledge of regulatory requirements and best practices, proactively identifying opportunities for process improvements and efficiencies. Qualifications Required: - Deep expertise in regulatory affairs for vaccines and biologics, with a proven track record of successful submissions and approvals in the US market. - Familiarity with regulatory frameworks in other stringent regimes such as the EU, Canada, UK, and Japan, demonstrating the ability to navigate diverse regulatory environments. - Strong communication and interpersonal skills, enabling effective collaboration with internal and external stakeholders. - Ability to work autonomously in a fast-paced environment, demonstrating resilience and adaptability in the face of evolving challenges. - Prior experience in regulatory work for authorized COVID-19 vaccines is highly desirable and will be considered a significant advantage. At PopVax, we offer competitive compensation, comprehensive health insurance coverage for your immediate family, and a supportive work environment focused on innovation and collaboration. If you are passionate about advancing scientific and clinical frontiers in vaccines and immunotherapies, and are driven by the prospect of making a meaningful impact on global health, we invite you to join our team and be a part of our mission to save lives through groundbreaking pharmaceutical science.,
As a senior synthetic chemist at PopVax, you will be responsible for designing and synthesizing novel lipids, especially cationic and ionizable lipids for nucleic acid delivery. Your expertise in this area will contribute to the development of mRNA-LNP formulations with desirable properties such as increased mRNA expression in vivo, enhanced thermostability, reduced reactogenicity and toxicity, and targeted delivery to relevant tissues and cell types. Your role will involve independently generating viable lipid designs and conducting high throughput in vitro screening of novel lipids and LNP formulations. Key Responsibilities: - Design and synthesize novel lipids, particularly cationic and ionizable lipids for nucleic acid delivery - Independently generate viable lipid designs for use in mRNA-LNP formulations targeting various desirable properties - Conduct high throughput in vitro screening of novel lipids and LNP formulations - Understand how changes to lipid design manifest in vivo Qualifications Required: - Demonstrated competence in de novo lipid design for nucleic acid delivery applications - Experience in designing novel charged lipids for mRNA-LNP formulations - Strong understanding of lipid design implications in vivo - Ability to work collaboratively in a multidisciplinary environment If you are passionate about advancing scientific, clinical, and regulatory frontiers of vaccines and immunotherapies, developing medicines with the potential to save millions of lives, and contributing to the growth of a global pharmaceutical company in India, PopVax is the place for you. Join our team and be part of our mission to develop novel vaccines and therapeutics that can save 1 million lives each year.,