Senior Scientist - Novel Lipid Design

As a senior synthetic chemist at PopVax, you will be responsible for designing and synthesizing novel lipids, especially cationic and ionizable lipids for nucleic acid delivery. Your expertise in this area will contribute to the development of mRNA-LNP formulations with desirable properties such as increased mRNA expression in vivo, enhanced thermostability, reduced reactogenicity and toxicity, and targeted delivery to relevant tissues and cell types. Your role will involve independently generating viable lipid designs and conducting high throughput in vitro screening of novel lipids and LNP formulations. Key Responsibilities: - Design and synthesize novel lipids, particularly cationic and ionizable lipids for nucleic acid delivery - Independently generate viable lipid designs for use in mRNA-LNP formulations targeting various desirable properties - Conduct high throughput in vitro screening of novel lipids and LNP formulations - Understand how changes to lipid design manifest in vivo Qualifications Required: - Demonstrated competence in de novo lipid design for nucleic acid delivery applications - Experience in designing novel charged lipids for mRNA-LNP formulations - Strong understanding of lipid design implications in vivo - Ability to work collaboratively in a multidisciplinary environment If you are passionate about advancing scientific, clinical, and regulatory frontiers of vaccines and immunotherapies, developing medicines with the potential to save millions of lives, and contributing to the growth of a global pharmaceutical company in India, PopVax is the place for you. Join our team and be part of our mission to develop novel vaccines and therapeutics that can save 1 million lives each year.,