R & D Department - Research Associate/ Research Executive

Gufic Group

3 - 8 years

3 - 8 Lacs

navsari

Posted:5 days ago| Platform:

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Skills Required

synthesis development process development peptides biotechnology research and development

Work Mode

Work from Office

Job Type

Full Time

Job Description

Role & responsibilities

Candidate must have throughout experience in Peptide process development
Must be familiar with the designing of peptide drug substances route of synthesis
Sound knowledge about the capping/cyclization of peptide chain
Knowledge about protection and Deprotection of amino acids
Knowledge about global deprotection of peptide form Peptidyl resin
Must be familiar about the isolation of crude peptide
Knowledge about the critical process parameters of solid phase Peptide synthesis
Basic knowledge about purification techniques for crude Peptide
9.Able to handle 100 mm DAC as on required
Must be familiar with peptide synthesis process scale up

Candidate must have experience in Peptide process development
Able to perform experiment as suggested by team leader
Knowledge about protection and Deprotection of amino acids
Knowledge about global deprotection of peptide form Peptidyl resin
Must be familiar about the isolation of crude peptide
Knowledge about the critical process parameters of solid phase Peptide synthesis
Basic knowledge about purification techniques for crude Peptide

Responsible for Column packing and un-packing activity for purification trials
Responsible for Column Performance Test (CPT)
Peptide & API Purification method development on preparative HPLC
Perform downstream-Purification of Crude Peptide on 100 mm DAC
Define pooling strategy/control strategy for Purification method
Preform salt exchange activity on 100 mm DAC
Generate report for Design of Experiment (DoE) for Purification
Co-work for solid phase up-stream synthesis
Perform and optimization of global deprotection of Peptidyl resin

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