Process Development Scientist

Key Responsibilities:

• Perform

  chemical reactions

  for the process development of

  Antibody Drug Conjugates (ADC)

  that connect an antibody with a potent drug (

  payload

  ) through a chemical bond in HPAPI facility or in ADC lab. Thereby, suitable prior experience is highly desirable.
• The selected candidate would handle highly potent active pharmaceutical ingredients (

  HPAPIs

  ) and

  cytotoxic compounds

  .
• Perform

  synthetic chemistry

  reactions, reaction work-ups, purification of the compounds by column

  chromatography

  ,

  crystallization

  , re-crystallization techniques, preparative

  TLC

  and operating lab instruments.
• Ensure that the samples generated during the course of synthesis are given for analysis and record subsequent results obtained and update the supervisor / group leader on the progress of synthesis and ensure samples are packed appropriately for shipment
• Record the observations of experiment/reaction, results, utilization of resources and other activities related to the reaction in the laboratory or e-notebook following guidelines and in timely manner and ensure that the same is handled safely and confidentially.