Scientist I, Protein Biology

Work Schedule

Environmental Conditions

Job Description

About Team: Antibody team

The antibody team is involved in engineering and development of antibodies, with a deep focus on reagent quality and specificity. The core activities of the team include design, development, purification, conjugation and testing of antibodies in a variety of immunoassay applications using pioneering tools and technologies. The goal of the program is advanced product development and creation of product specific information to promote research use.

Role & Responsibilities

Role:

To be an integral part of an antibody development team with a focus on performance and specificity using innovative molecular, protein, biochemical and cell biology methods.

Responsibilities:

• Meticulous experimental planning and execution to meet program goals.
• Timely record keeping of results into data sheets and laboratory note-books.
• Regular mining of literature and keeping oneself up to date with developments in field of antibody development.
• Compilation and presentation of data in written and oral formats. Active participation in team meetings.
• Attention to detail and adherence to schedules.

Candidate Requirement:

Education & Experience levels:

Applicants should have Masters with 0-4 years confirmed experience or a PhD in a life sciences field (submitted within the last one year) with a strong focus on protein biology, protein design, protein purification, antibody or protein conjugations, molecular biology, immunology, biotechnology or biochemistry.

Nature of experience:

• Characterization of antibodies using SDS-PAGE, SEC-HPLC and validating them in immunoassays such as ELISA, western blot and IF.
• Hands on experience in performing protein purification using affinity, ion-exchange and size exclusion chromatography.
• Experience with various formats of antibodies such as full length, Fab, VHH etc.
• Experience in automated purification method development in AKTA, NGC and liquid handler
• Experience or familiarity with antibody or protein engineering, rational design of mutants, and molecular biology.
• Strong theoretical and working knowledge in protein expression, protein purification and antibody purification.
• Experience with structural biology and protein modeling and visualization tools such as Pymol, Shrodinger, Discovery Studio or other such programs is desirable.
• Theoretical or practical experience in antibody development platforms is desirable.
• Project or work experience in support of relevant skills such as publications, project reports or thesis work.
• Proficient in MS Office applications such as Word, Powerpoint, Excel and possess a strong statistical knowledge and familiarity with statistical software such as Prism.

The successful candidate will be self-motivated and a self-starter who is excellent at learning and applying new concepts for process or product improvements, possess excellent oral and written communication skills to connect to peers and leadership, and will be an excellent teammate with the ability to work with diverse colleagues.

Thermo Fisher Scientific is an equal opportunity employer and value diversity at our company. All qualified applicants will receive consideration for employment without discrimination basis race, color, religion, sex, sexual orientation, gender, gender identity or expression, national origin, protected veteran status, age, genetics, pregnancy, disability or any other legally protected status. Thermo Fisher Scientific aligns with all applicable equal employment opportunity legislation in each jurisdiction in which it operates.

We offer competitive remuneration, annual incentive plan bonus, healthcare, and a range of employee benefits. Thermo Fisher Scientific offers employment with an innovative, forward-thinking organization, and outstanding career and development prospects. We offer an exciting company culture that stands for integrity, intensity, involvement, and innovation!

ThermoFisher is committed to crafting a diverse work environment that values and respects individuals from all backgrounds. Thermo Fisher Scientific is an EEO/Affirmative Action Employer and does not discriminate on the basis of race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability or any other legally protected status.