Title: Executive - API R&D

Role:

To execute activities related to R&D Peptide Process Development & Scale-ups, along with a group comprising of Research Officers/ Research Assistants in co-ordination with Team/Group Leader

Details of Previous Work Experience (Mandatory Requirement)

• Literature search and ROS (Route of Synthesis) finalization
• Basic knowledge of Orthogonal protected amino acid and Peptide
• Solid phase peptide Synthesis/Oligonucleodtide Synthesis
• Handling of hazardous chemical like Trifluoroacetic acid
• Knowledge of handling of analytical HPLC/Oligo Synthesis
• Purification using Preparative HPLC
• Preparative column packing and usage.
• Computer literacy etc.
• Knowledge of Phosphoramidalin /handling/storage

Job Description:

• Literature search with respect to assigned project and finalizing the non-infringing synthetic route

• Experimentation (Process development, DoE study, optimization and validation).

• Purification of Peptide and knowledge of lyophilisation of pure solution.

• Handling of analytical HPLC and preparation of buffer.

• Characterisation of Peptide using HRMS,2D NMR, IR, Peptide mapping and sequencing.

• Preparation of Technology transfer documents.

• Scaling-up of process developed at R&D.

• Assisting to RA in filing DMF.

• General Laboratory Management etc.