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Executive - API R&D

Executive - API R&D

SUN PHARMA

3 - 7 years

0 Lacs

vadodara gujarat

Posted:15 hours ago| Platform: Shine logo

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Skills Required

hrms ir sequencing literature search ros route of synthesis finalization orthogonal protected amino acid peptide solid phase peptide synthesis oligonucleodtide synthesis handling of hazardous chemical trifluoroacetic acid analytical hplc oligo synthesis purification using preparative hplc preparative column packing phosphoramidalin technology transfer documents 2d nmr peptide mapping laboratory management

Work Mode

On-site

Job Type

Full Time

Job Description

You will be responsible for executing activities related to R&D Peptide Process Development & Scale-ups, working alongside a team of Research Officers/ Research Assistants under the guidance of the Team/Group Leader. Your main tasks will include conducting literature searches and finalizing the Route of Synthesis, applying basic knowledge of Orthogonal protected amino acid and Peptide, performing Solid phase peptide Synthesis/Oligonucleodtide Synthesis, handling hazardous chemicals like Trifluoroacetic acid, managing analytical HPLC/Oligo Synthesis, purifying compounds using Preparative HPLC, packing and using preparative columns, and ensuring computer literacy. Additionally, you will need to have knowledge of Phosphoramidalin handling and storage. Specific duties will involve conducting literature searches for the assigned project and finalizing a non-infringing synthetic route, conducting experiments such as process development, DoE studies, optimization, and validation, purifying Peptide compounds, and being familiar with lyophilization processes. You will also handle analytical HPLC, prepare buffers, characterize Peptides using HRMS, 2D NMR, IR, Peptide mapping, and sequencing, prepare Technology transfer documents, scale-up processes developed at R&D, assist in filing DMF, and manage general laboratory operations. Overall, your role will be crucial in the successful execution of R&D Peptide Process Development & Scale-ups, contributing to the advancement of the team's projects and objectives.,

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Executive - API R&D