Job
Description
Are you ready to make a significant impact in the world of drug discovery and development Join AstraZeneca's Clinical Pharmacology & Safety Sciences (CPSS) department, where innovation meets collaboration. Our Safety Innovation team is at the forefront of advancing a diverse pipeline across therapeutic areas, delivering safety science from early discovery through clinical development. We are seeking a talented in vitro pharmacologist to join our Secondary Pharmacology team, contributing to the clinical advancement of new medicines. In this pivotal role, you'll leverage your expertise in pharmacology, toxicology, and biology to collaborate with drug safety specialists and project safety pharmacologists. Your insights will shape drug design during the early phases of discovery, ensuring the selection of safer molecules and developing strategies to mitigate safety risks. You'll generate in vitro pharmacological profiling data at contract research organizations (CROs), identify off-target risks, and interpret pharmacological interactions. Your work will translate in vitro activity into pre-clinical and clinical adverse events, providing crucial guidance for project decisions. PhD or Masters or equivalent experience in a relevant scientific field with 4+ years of industrial experience is required. A strong background in pharmacology (e.g., pharmacology, biology, biochemistry, toxicology, physiology) with a proven track record in driving innovative science, preferably in the pharmaceutical or biotechnology industry is essential. Technical experience in in vitro pharmacological or biochemical assay development and screening (e.g., kinase profiling technologies, radioligand binding, enzyme activity, and functional cell-based systems) applied to various biological target classes is a must. Excellent problem-solving and organizational skills, delivery focus, and outstanding communication skills are necessary. A true collaborator with highly effective networking skills and experience collaborating across scientific disciplines, cultures, and expertise is preferred. Experience with off-target profiling data and strategies in the pharmaceutical industry, practical understanding of kinase profiling technologies, experience working with CROs, commissioning requests and driving delivery processes, experience with being entrepreneurial taking the initiative in projects, demonstrated leadership in scientific projects or teams, experience in regulatory interactions or safety assessments, and knowledge of emerging trends in drug safety and pharmacovigilance are desirable skills/experiences. When we put unexpected teams in the same room, we unleash bold thinking with the power to inspire life-changing medicines. Join us in our unique and ambitious world at AstraZeneca, where we are driven by curiosity and courage, exploring what science can achieve. Our commitment to making a difference is unwavering as we fuse data and technology with scientific innovation to tackle some of the world's most complex diseases. With opportunities for lifelong learning and career growth, AstraZeneca is where you can push boundaries and deliver life-changing medicines. AstraZeneca embraces diversity and equality of opportunity, building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. Join us now and be a part of a team that transforms patient lives through groundbreaking science.,
