Job Title: Associate Director, PKPD / Pharmacometric Data/SAS Programmer Career Level - E Introduction to Role: Are you ready to make a significant impact in the world of drug development? We are seeking an Associate Director for, PKPD / Pharmacometric Data/SAS Programmer belonging to the Clinical Pharmacology and Quantitative Pharmacology programming team. This role focuses on all aspects of data preparation, programming, validation, and diagnostics to support Pharmacometric and clinical pharmacology analyses at the study and project levels. You will be instrumental in influencing critical decision making throughout all phases of drug development and regulatory interactions. Accountabilities: As an Associate Director, you will be accountable for expert data integration, manipulation, and preparation results at the study and project level. You will execute state-of-the-art data preparation techniques with direct value for the study and/or project. Your responsibilities will include collating, cleaning, and preparing analysis-ready data for Pharmacometric Modeling and Simulation (M&S) software (e.g. NONMEM) to influence study designs and go/no-go decisions. You will also contribute to regulatory documents and interactions, internal initiatives to develop the Pharmacometric discipline, and compliance with Good Clinical Practice (GCP) regulations. Essential Skills/Experience: 10+ years of hands-on experience in SAS programming. Strong understanding of pharmacokinetics, pharmacodynamics, and their application in drug development. Strong SAS/R programming skills Expert knowledge of data preparation and programming practices (CDISC, SDTM, ADaM) Demonstrated data programming and clinical development expertise Good knowledge of global regulatory, compliance, processes, standards Capability to develop tools to support data integration & visualization Bachelors degree MS preferred with relevant experience required Demonstrated experience in regulatory submissions and interdisciplinary team leadership Varied programming languages (SAS, R, Python) Experience in early and late-stage drug development Excellent problem-solving, communication, and project management skills. Proficient oral and written English communication skills Knowledge in pharmacology, drug targets and core Therapy areas (e.g. Oncology, Respiratory, Renal Metabolism etc.) Quantitative/Scientific background (Statistics, Engineering, Biological Science) Desirable: Demonstrated expertise in data preparation and programming to support Pharmacometric Modeling and Simulation (M&S) software (e.g. NONMEM, Monolix, R, Matlab) Scientific publishing in the field on pharmacometrics When we put unexpected teams in the same room, we unleash bold thinking with the power to inspire life-changing medicines. In-person working gives us the platform we need to connect, work at pace and challenge perceptions. That's why we work, on average, a minimum of three days per week from the office. But that doesn't mean we're not flexible. We balance the expectation of being in the office while respecting individual flexibility. Join us in our unique and ambitious world. Why AstraZeneca? Join our Biopharmaceuticals R&D team and be part of a team where you are empowered to follow the science. At AstraZeneca, we are unlocking the power of what science can do. We are working towards treating, preventing, modifying and even curing some of the world's most complex diseases. Here we have the potential to grow our pipeline and positively impact the lives of billions of patients around the world. We are committed to making a difference and have built our business around our passion for science. Now we are fusing data and technology with the latest scientific innovations to achieve the next wave of breakthroughs. Ready to make a difference? Apply today and join us in pushing the boundaries of science to deliver life-changing medicines!

Serves as a Subject Matter Expert (SME) within the PS Technical Solutions Team for reporting systems, ensuring they are capable of delivering high quality expertise and services across the PV systems estate, ensuring prioritized requirements and the strategic goals of stakeholders are understood and supported. Manages applicable tools, documentation and methodologies to ensure the reporting needs of organization are fully addressed and supported. Responsibilities of PV systems inclusive of relevant system processes, ensuring that the: System is changed in an effective and timely manner to meet new health authority requirements and / or changed business demands (e.g. divestment, in-licensing, partnership etc.). Technical components of the system are upgraded in a compliant and risk-minimized manner. Lead and coordinate routine system maintenance activities (e.g. MedDRA, WHODD, Ontology updates) System enhancement requests are identified and prioritized (change control and major change projects). Access to data is controlled, training requirements are defined and use of the system is compliant with all applicable regulations. User support arrangements (e.g. training, helpdesk) and Service Level Agreements are in place, irrespective of whether delivered internally or by external vendors / providers. Supports the ongoing business utilization of PS systems, including troubleshooting problems and developing solutions. Provides technical input and guidance on the development of strategic plans for PS systems across the enterprise. Evaluates new modules and software upgrades and assesses the impact on system validation, the user community and PV processes. Retains a global perspective around the business need for accurate, high-quality, effective and efficient information, while maintaining a focus on regulatory and corporate compliance needs. Anticipates business, regulatory and wider industry trends, and apply these in the evolution and development of safety solutions. Accountable for ensuring the quality of business-related content of relevant improvement project proposals and associated documentation in line with Company goveranance process requirements. Contributes to the development of procedures, work instructions, system specifications related to the use GPS information sources and toolsets. Participates in interactions with interal and external partners and health authorities on electronic safety data exchange. Supports the GPS as required in the license partner/CRO pharmacovigilance agreement (PVA) process. Essential Skills/Experience Bachelor s degree in a scientific discipline with relevant experience in supporting safety-related activities in clinical biopharmaceutical development. Significant experience (10+ years) in pharmacovigilance with a proven record of supporting safety tools/solutions. Proven competence in designing, delivering, deploying, or maintaining information/systems solutions in support of safety. Broad knowledge of safety information tools required to support drug development and marketed brands within AstraZeneca. Ability to articulate complex safety-related business needs in the context of IS systems design, architecture, and development. Significant experience in system validation, audit, and PV inspection activities and requirements. Excellent interpersonal and communication skills with the ability to efficiently communicate with all levels of the organization. Desirable Skills/Experience Higher degree in a clinical or safety-related discipline. Awareness of broader technological developments leveraged to inform the design and development of AZ PV Systems. Ability to identify opportunities for continuous improvement based on strong awareness of external competitive practice. Ability to lead diverse teams across multiple geographies to deliver on objectives. Experience across multiple therapeutic or business areas or in safety-related roles within other biopharmaceutical, regulatory, or health organizations. Knowledge of procedures governing clinical trial data with health authorities worldwide and experience implementing these within the business. Experience working across different geographic locations, organizations, and cultures.

Support development of technical programming specifications for SDTM, ADS or ADaM standards. Independently develop and/or validate programs that generate SDTM, and analysis datasets based on Alexion or ADaM specifications. Support development and validate technical programming specifications for tables, listings, figures/graphs based on Protocol and SAP. Independently develop and validate programs that generate tables, listings, figures/graphs using Alexion specifications. Manage external vendors and contract programmers. Provide project progress updates of programming activities. Review, maintain, and approve protocol specific documents as necessary. Provide guidance and mentoring to peer, junior-level Programmers and contract staff. Support project leadership ensuring that department standards are implemented in all studies. Contribute ideas and thoughts towards the optimization of standard operating procedures. Lead team meetings when appropriate. Any other activities as required. Essential Skills/Experience: Minimum of 6 years of statistical programming experience in the Pharmaceutical, Biotechnology, or Contract Research Industry. Proven ability to: Develop and validate technical specifications and programs for safety and efficacy analysis datasets, tables, listings, and figures/graphs. Independently and collaboratively resolve problems Clearly communicate processes and standards with management and team members High competence in using SAS/Base, SAS/Macro, SAS/STAT. Knowledge of SAS/Graph, and SAS/SQL Knowledge and implementation of: SDTM and ADaM principals Relational Databases. Good Clinical Practice principals. Good Programming Practice principals. 21CFR Part 11 Standards principals. Integrated Summary Safety/Efficacy Analyses. Safety data and Coding Dictionaries (MedDRA and WHODD). ICH eCTD format.

The Axial programme needs the best talent to work in it. Whether it s the technical skills, business understanding or change leadership, we want to ensure we have the strongest team deployed throughout. We are aiming to deliver a world class change programme that leaves all employees with a fuller understanding of their role in the end-to-end nature of our global company. This programme will provide AZ with a competitive edge, to the benefit of our employees, customers and patients. Join Axial as an Engineer and help build cutting-edge pipelines and visualizations on our new SAP analytics stack using Datasphere and SAP Analytics Cloud. Be part of a self-sufficient, agile team creating high-impact, reusable data products and dashboards that drive business decisions. With opportunities to work across data pipelines, modeling, testing, and more, this is your chance to shape the future of enterprise analytics while advancing your skills with world-class tools! We are looking for engineers who want to build pipelines and visualisations on the new SAP analytics stack (Datasphere and SAP Analytics Cloud). We are building out teams to face key finance and operations process areas. And, more importantly for this advert, we are building out an enterprise team to build and run the cross-cutting data products and dashboards. Data products like dimensions for business partner, material master, cost centre, profit centre, location and geography; or fact tables for complex multi-process reporting and exports to other data hubs. This team will be self-sufficient, so you will get experience of everything - data pipelines, data analysis, data modelling, testing, incident management. The team will work in a transparent and agile way, meaning there will be a published roadmap of analytics products and a constant flow of new work from across the Axial program and AZ. You will be part of a team that creates the most re-used analytics artefacts on the stack. This means you need to have a passion for well-engineered analytics. You are likely to have experience of some (but not all) of the following: ETL tooling; data modelling; SAP analytics tooling; dashboard creation; analytics best practices; data warehousing; data modelling; analytics testing; SAP data. We will provide training on SAP Datasphere and SAP Analytics cloud. Desirable experience: ETL tooling / data pipeline tools, Data modelling, SAP data and associated business processes, SAP Datasphere, SAP Analytics Cloud, Dashboard creation, Analytics best practices, Data warehousing, Analytics testing.

Dive into the world of pharmacovigilance by supporting the processing and handling of ICSRs, including adverse event reporting from clinical and post-marketed sources for AstraZeneca products. Engage with Health Authorities for ICSR-related queries and contribute to the operational implementation of the Quality Management System. Youll manage procedural document management, AE/PV training requirements, quality incident reporting, and audit readiness. Collaborate on PV aspects related to Organised Data Collection Programmes, Digital and Social Media activities, and partnerships with external parties. Provide Patient Safety expertise within the local Marketing company, tackling issue management for key products, risk management, and action plan formulation. Participate in ad-hoc local Marketing Company projects to drive success. Essential Skills/Experience: Degree Qualified - Pharmacy/ Medical/ Science Pharmacovigilance knowledge excellence Good Pharmacovigilance Practice Knowledge of health authority regulations Cross functional collaborative approach Effective and lateral thinking Problem solving Vendor management Excellent attention to detail Excellent written and verbal communication skills Desirable Skills/Experience: Influencing, and Conflict Resolution skills. Medical knowledge in company Therapeutic Areas Project management Successful participation in above-market projects Audit & Inspection experience

Your key responsibilities will include leading and managing a local case intake team, overseeing the intake, processing, and reporting of Individual Case Safety Reports (ICSRs), and ensuring timely and accurate processing of patient safety cases. Youll monitor local case intake metrics, prepare reports on key performance indicators, and identify areas for improvement. Staying updated on pharmacovigilance regulations, participating in audits, conducting quality checks, and serving as a liaison between local and global levels are also part of your role. Additionally, youll participate in ad-hoc projects related to case handling. Essential Skills/Experience: Degree Qualified - Pharmacy/ Medical/ Science Thorough knowledge and experience of pharmacovigilance within the pharmaceutical industry Thorough knowledge of the current pharmacovigilance and regulatory developments Experience in working cross-functionally Ability to set and manage priorities, resource goals and project initiatives Ability to influence strategically to obtain desired outcomes while maintaining effective, positive organisational relationships Excellent attention to detail Excellent written and verbal communication skills Desirable Skills/Experience: Degree Qualified - Pharmacy/ Medical/ Science Thorough knowledge and experience of pharmacovigilance within the pharmaceutical industry Thorough knowledge of the current pharmacovigilance and regulatory developments Experience in working cross-functionally Ability to set and manage priorities, resource goals and project initiatives Ability to influence strategically to obtain desired outcomes while maintaining effective, positive organisational relationships

Main Duties and Responsibilities Effectively implement sales strategy and tactics, plan of action (POA) in accordance with company policies. Regularly monitor territory s sales performance to initiate appropriate actions to ensure performance is in line with objectives. Facilitate enlistment of newly launched and key products in hospitals and clinics. Conduct analysis of market/competitors to identify territory business opportunities Participate in promotional activity programs to increase product awareness in the market. Update territory customer classification, database and call records continuously Build trust and credibility with customers by demonstrating professionalism acting within the AZ Code of Conduct Identify areas for self-development and discuss developmental needs with FLSM Essential Requirements Graduate degree in Science/Pharma Passion for Sales Interpersonal, influencing and negotiation skills Excellent Communication Skills Good Planning and Organisational Skills Excellent Scientific knowledge Ability to develop Strategic Partnerships

Training Programme Development Design, develop, and implement training programmes tailored to GBS and client goals and employee needs Create engaging training materials, specifically for GBS induction, including manuals, e-learning modules, and workshops Continuously evaluate the GBS training effectiveness and make improvements based on feedback Employee Development & Skills Enhancement Identify skills gaps and develop strategies to enhance employee competencies Work with Regional and local MC L&D resource to ensure GBS employees maintain relevant competencies to support our client s needs Organise onboarding programmes for new hires to ensure a smooth transition into the company Training Delivery & Coordination Coordinate GBS employees relevant, and ongoing training content and sessions in collaboration with client L&D trainers Conduct training sessions in-person, online or through a blended learning approach Work with subject matter experts to ensure accuracy and relevance of existing and future training content Performance Evaluation & Compliance Assess training impact through feedback, assessments, and key performance indicators (KPIs) Ensure all training programmes follow industry regulations and company policies Keep up to date with standard methodologies in corporate training and learning technologies Ensure all GBS Patient Safety colleagues complete all mandatory training on time and to required standard Sustainability and Training Quality Assurance Audit and review training materials for accuracy, relevance, and compliance with industry and the client s standards Maintain training content integrity and ensure long-term learning effectiveness Maintain accurate records of training and training completion for quality management and audit purposes Lead the GBS Patient Safety Training Centre of Excellence (CoE) through sharing best practice and proactively promoting learning and development opportunities Support the GBS Leadership Team in projects and initiatives to help the Business achieve goals and objectives Essential Skills/Experience Bachelors degree in human resources, Business Administration, education or a related field 3+ years of experience in training, learning and development, or human resources Strong presentation skills and effective delivery of L&D practices Cross functional collaborative approach Effective and analytical thinking with the ability to measure and assess the effectiveness of training initiatives Problem solving Excellent attention to detail Excellent written and verbal communication skills Desirable Skills/Experience Experience in corporate training, instructional design, or leadership development Experience in Pharmacovigilance, Patient Safety or similar industry Influencing, and Conflict Resolution skills. Successful participation in above-market projects Familiarity with Learning Management Systems and e-learning tools

- Serve as the Lead Programmer and Manager of the statistical programming efforts. - Develop and validate technical programming specifications for analysis datasets using Alexion or ADaM standards. - Independently develop and validate programs that generate analysis datasets based on Alexion or ADaM specifications. - Develop and validate technical programming specifications for protocol-specific efficacy tables, listings, figures/graphs. - Independently develop and validate programs that generate protocol-specific efficacy tables, listings, figures/graphs using Alexion specifications. - Ensure that the filing of study documentation is maintained to the standard required according to processes and acceptable for audit. - Directly support the Clinical and Statistical Programming Director in all aspects of the management and development of the Statistical Programming team. - Participate in the ongoing review of the processes used by the Statistical Programming group to ensure processes are continually complied with and updated as necessary. - Create and/or review programming plans, and ensure appropriate resource allocation and prioritization. - Act as the primary department contact to ensure that department standards are implemented in all studies. - Manage adherence to all company policies, SOPs, and other controlled documents; ensure all programming activities adhere to departmental standards. - Collaborate closely with Biostatistics, Clinical Data Management, Pharmacovigilance, Clinical Operations, and other functions within Alexion to address their needs for programming support. Essential Skills/Experience - 7+ years statistical programming experience in the CRO or Pharmaceutical Industry. - 4+ years project management experience in the CRO or Pharmaceutical Industry. - Experience with CDISC SDTM and ADaM models and transforming raw data into those standards. - Strong people management skills and supervisory skills gained from direct line management or supervisory experience. Proven abilities to lead and manage cross-functional projects, and people, from concept to completion. - Strong verbal and written communication skills - ability to clearly and effectively present information. - An excellent understanding of the roles and responsibilities of all related disciplines, in particular Biostatistics, Clinical Data Management, and Pharmacovigilance. - Advanced knowledge of SAS/Base, SAS/Macro, SAS/STAT, SAS/Graph, and SAS/SQL in a windows environment with a demonstrated mastery of SAS/STAT procedures. - Extensive experience and proven skills in the use of SAS within a Statistical Programming environment to develop and validate analysis datasets, tables, listings, and figures/graphs. - Knowledge of clinical database design, specifically electronic data capture using Inform, Medidata, and Oracle. - Advanced experience with: - Constructing technical programming specifications. - Relational Databases. - Good Clinical Practices. - Good Programming Practices. - 21CFR Part 11 Standards. - Integrated Summary Safety/Efficacy Analyses. - Creating all files necessary to support an electronic submission in the eCTD format. Desirable Skills/Experience - BS/MS/MA in Statistics, Biostatistics, Computer Science, Mathematics or related area. - Competencies: - Accountability - Collaboration - Decision Quality - Drive for Results - Perseverance - Problem Solving - Informing - Peer Relationships - Time Management - Building Effective Teams - Managing Through Systems

Essential Skills/Experience: Medical degree (eg MD, MBBS) At least 2 years of clinical experience post-registration High level of medical competence, with an ability to balance this with industry standards to achieve business goals Minimum 3 years of Patient Safety experience (Pharmacovigilance) (with clear evidence of delivery) Desirable Skills/Experience: Able to work across TAs and Functions Experience of supervising Patient Safety colleagues A demonstrated ability to understand epidemiological data Skills and Capabilities: Commitment to Customers and Integrity Strategic Leadership Acts Decisively Drives Accountability Works Collaboratively Develops People and Organisation May train or mentor junior level staff within given role Technical: Drug Development Experience and Application of Disease and TA knowledge Integrative thinking Excellence in pharmacovigilance Patient Benefit risk assessment Core: Conceptual thinking Influencing Initiative Innovation Business relationship management

As a Senior Consultant, youll be responsible for: Contributing to the development and implementation of front-end architecture using ReactJS. Supporting technical direction, ensuring adherence to standard methodologies, and backing continuous improvement initiatives. Collaborating with project managers to define project scope, timelines, and deliverables. Working closely with back-end developers, UX/UI designers, and other stakeholders. Supporting junior developers and fostering a collaborative team environment. Essential Skills/Experience: Experience: 6 to 10 years. Technical Proficiency: Expertise in JavaScript, TypeScript, HTML5, CSS3, and related front-end technologies. React Native Expertise: Demonstrated experience in developing mobile applications using React Native. State Management: Hands-on experience with state management libraries such as Recoil, Redux, or Context API. API Integration: Familiarity with RESTful APIs and web services integration. Responsive Design: Solid understanding of responsive design principles and mobile-first development. Build Tools: Experience with front-end build tools like Webpack, Babel, and NPM/Yarn. Version Control: Knowledge of modern version control systems, particularly Git. Testing and Quality Assurance: Proficiency in unit and integration testing with frameworks such as Jest, Mocha, or React Testing Library. End-to-end testing experience with Cypress or Appium (for mobile) is also a plus. Security Best Practices: Knowledge of security practices for web applications, including OWASP standards, cross-site scripting (XSS) prevention, and handling sensitive data securely. Authentication & Authorization: Experience with OAuth, JWT, or similar authentication mechanisms, particularly in healthcare settings. UI/UX Design Principles: Familiarity with accessibility standards (e.g., WCAG) and an understanding of accessible design for diverse users. Knowledge of design tools like Figma, Sketch, or Adobe XD is beneficial for effective collaboration. Performance Optimization: Skills in optimizing application performance, including bundle size reduction, load time improvements, and mobile performance profiling in React Native. Analytics and User Behavior Tracking: Experience integrating analytics tools such as Google Analytics, Mixpanel, or Firebase for tracking user engagement and application performance. Client Interaction Skills: Strong client-facing skills and experience managing stakeholder expectations, which are crucial for consultants working directly with clients. Healthcare Data Compliance: Awareness of healthcare regulations, such as HIPAA for U.S.-based projects, and best practices for securely handling patient data within digital applications. Problem-Solving: Excellent problem-solving skills and attention to detail. Communication Skills: Strong communication and interpersonal skills. Multi-tasking: Ability to manage multiple tasks and projects simultaneously. Agile Methodology: Experience with Agile/Scrum methodologies. DevOps Awareness: Familiarity with DevOps practices and CI/CD pipelines is desirable. Bonus Skills: Knowledge of back-end technologies (Node.js, Express) is a pl

Key Duties and Accountabilities Develop account strategy and plans Identify opportunities and strategies to improve positioning of AZs R&I products at a local level. Work with Sales Manager to develop a local strategy and business plan to meet targets and further improve positioning of AZs R&I products at a local level. Create deep stakeholder relationships Engage R&I HCPs in dialogue about approved indications, product efficacy / safety profiles and treatment protocols to support on-label prescribing for appropriate patients. Establish and maintain ongoing, long term collaborative relationships with stakeholders. Share stakeholder insight and information within AZ to strengthen relevant activities, e.g., product development, marketing, sales efforts. Build capability and knowledge in healthcare eco-system Build knowledge and understanding about AZs overall R&I value proposition, and products labeled indications and efficacy data among all relevant stakeholders in the MDT and DMU. Utilize different communication approaches, techniques, and channels to help build knowledge in the MDT and DMU, including. Conduct science-based discussions with the HCP as per the approved indications of AZs products. Arrange multidisciplinary workshops for physicians and other healthcare professionals. Arrange and coordinate effective speaker programmes with physician advocates and KOLs. Actively support R&I nurses on relevant trainings, e.g., chemotherapy, testing solutions. Deliver on plans and achieve sales goals on budget Drive sales performance and ensure sales forecasts meet or exceed expectations while managing assigned budgets. Successfully promote the benefits of AZs R&I brands, using fair balance messages and the appropriate mix of promotional tools. Ensure AZs products are optimally utilized in line with national/local guidelines and the product license. Be compliant Successfully complete all training requirements, including product examinations. Comply with all external regulations and internal policies. Ensure compliance with the AZ Code of Ethics, Global External Interactions Policy and Standards, and Privacy Policy and Standards, especially when interacting with Patient Groups. Essential for the role University Science graduate, ideally MBA from reputable institute. Proficient in oral and written communication (English). Must have 3+ years of sales experience with Pharma sector in R&I domain. Should have been a high performer in sales, Cross functional engagement, strong business acumen. Organizational skills, good analytical skills / mind set, ability to manage complexity with a high degree of maturity.

Key Duties and Accountabilities Develop account strategy and plans Identify opportunities and strategies to improve positioning of AZs R&I products at a local level. Work with Sales Manager to develop a local strategy and business plan to meet targets and further improve positioning of AZs R&I products at a local level. Create deep stakeholder relationships Engage R&I HCPs in dialogue about approved indications, product efficacy / safety profiles and treatment protocols to support on-label prescribing for appropriate patients. Establish and maintain ongoing, long term collaborative relationships with stakeholders. Share stakeholder insight and information within AZ to strengthen relevant activities, e.g., product development, marketing, sales efforts. Build capability and knowledge in healthcare eco-system Build knowledge and understanding about AZs overall R&I value proposition, and products labeled indications and efficacy data among all relevant stakeholders in the MDT and DMU. Utilize different communication approaches, techniques, and channels to help build knowledge in the MDT and DMU, including. Conduct science-based discussions with the HCP as per the approved indications of AZs products. Arrange multidisciplinary workshops for physicians and other healthcare professionals. Arrange and coordinate effective speaker programmes with physician advocates and KOLs. Actively support R&I nurses on relevant trainings, e.g., chemotherapy, testing solutions. Deliver on plans and achieve sales goals on budget Drive sales performance and ensure sales forecasts meet or exceed expectations while managing assigned budgets. Successfully promote the benefits of AZs R&I brands, using fair balance messages and the appropriate mix of promotional tools. Ensure AZs products are optimally utilized in line with national/local guidelines and the product license. Be compliant Successfully complete all training requirements, including product examinations. Comply with all external regulations and internal policies. Ensure compliance with the AZ Code of Ethics, Global External Interactions Policy and Standards, and Privacy Policy and Standards, especially when interacting with Patient Groups. Essential for the role University Science graduate, ideally MBA from reputable institute. Proficient in oral and written communication (English). Must have 3+ years of sales experience with Pharma sector in R&I domain. Should have been a high performer in sales, Cross functional engagement, strong business acumen. Organizational skills, good analytical skills / mind set, ability to manage complexity with a high degree of maturity.

Roles & Responsibilities: Ensure Zero breach in the SOTC Process Agility in purchase order execution with mitigation of Risks Detailed reading ofTender, Rate Contract andPurchase Orders terms and conditions and mitigate the risks with right external & internal consents. Validate the Purchase Orders with internal references and Regularization of the Purchase Orders Coordinate with CFTs (Tender / Sales / Finance / Distribution / and Quality) for the execution of Purchase Orders Timely communications to theinternal and external stakeholders on the purchase orderrelated issues/Status Ensuring to keep sufficient stock inventories at the sales depots by coordinating with the Sales Team. Prepare andsubmitthe documentsas per terms oftender, rate contract and purchase orderswith all thesuppliesfor the paymentrealization against thepurchase order. Preparation of monthlydashboards on the purchase order executions and pending order details with the internal stakeholders. Coordinate with Tender Support for the Security Deposits for the Rate Contract finalization and Purchase Order Execution. Filing all the purchase order related documents and support the internal and external audit process. Skills Required: Assertiveness : follow the process and execute the job within the SOP Attention to details &Problem Solving : should be able to understand the challenge in hand and support with the solutions asan optionto the CFT. Communication : effective in verbal and written communication. Collaboration: Person should have the good collaboration mindset anda great teampayer. Proactiveness & Time Management : Should be able to pre-empt thenext bottle necks and work proactively to resolve the issue intimelymanner with race against the time mindset. EssentialEducationalQualification: B Pharmacy/bachelor s degreewith relevant experience in the SOTC AdvancedMicrosoftOffice Desirable: Experience in Pharma SOTC process will be anadvantage. Experience in tender operations/Pharma Operations (Supply chain/procurement) will be an advantage.

Building Brands / Therapy Support achievement of Market Shareobjective, bottom-line targets, top line & profitability Analysemarket conditions and forecast sales and market share. Continually provide customer feedback and macro view of the market through designated meets to achieve company s Long,Medium and Short termmarketing plans Percentage increase in market share for portfolio Achievement of sales targets Review of strategies with functional head Cost vs budget analysis Completion of product strategic and tactical Plans, and Monitors the implementation Develops and delivers key brand /indicationlevel promotional assets relevant to market needs. Ensures market model are in line with global templates / standard Brand Plan template Monitors sales and product supply,ensures forecasts areadjustedas necessary. Tracks implementation plan with sales management to ensure achievement of targets. Regular reviews of global templates and marketing guidelines Review of strategies with functional head Achievement of budget spending according to plan Regular forecast adjustment such that forecasting desired accuracy Relationship building with key external stakeholders, and builds AZ networking Works toidentifythe key stakeholders and KOLs in the therapeutic area Establishes regular contact with key stakeholders, especially KOLs. Systems in place for targeting key stakeholders and KOLs Achievement of agreed number of contact and receives product/brand manager contact reports Take feedback from key stakeholders and KOLs Maintain and improve systems and processes Tracks monthly performance vsbudget, andanalysereasons for gaps. Completes andsubmitsmonthly summary of performance, including activities and A&P against the plan. Streamlines reporting system and re-evaluatethe necessity of reports asrequired. Ensures completion of expense reports by team. All reportssubmittedareaccurate, data interpreted (actual vs budget) New improvements/initiatives in place Launch planning & execution support Support the development of relevant launch plan aligned to their respective tumor / brand Work effectively with the cross-functional team to support development of world class launch plans. Adherence to AZ and industry code of conducts,ethicsand code of marketing practice Ensures compliance from all stafftoguidelines, codes,policiesand procedures. Ensures compliance with AZ code of conduct. Ensures that company confidentiality ismaintained(i.e.intellectual property, product, strategic and salary information). Discloses potential breach of codes orconducts. No non-compliance issues raised with local and global policies and procedures Less than 2 complaints from competitors against marketing practice No breach of confidentiality All disclosures are investigated and resolved Strong Alignment to sales functions. Strong Alignment to sales functions. Collaboration with Sales team for effective and result oriented execution Education, Qualifications,Skillsand Experience Essential University graduate, ideally MBA fromreputableinstitute. 3 to 6 years commercial experience in Oncology TA is must, including 2-3 years of experience in brand/marketing Proficient in oral and written communication (English). Desirable Experience of alliance management in co-marketing / Co- promotion Prior experience in prelaunch &commercialising(preferably inglobalbrand). Worked with prior experience in MDT management and Peri operative Tx settings Key personal capabilities and attitude Key Functional Capabilities Excellent Communication Skills Good Planning andOrganisationalSkills Excellent Scientific knowledge Ability to develop Strategic Partnerships Preferably having launch experience in oncology segment Through understanding of institution business and preferably state govt segment Demonstrate AZ Values Consistently We follow the science We put patients first We play to win We do the right thing We are entrepreneurial Key Relationships to reach solutions Internal (to AZ or team) Sales Management and Field Force Medical and Regulatory departments Marketing colleagues Finance HR Supply Chain Global/regional groups

Typical Accountabilities: Ensures the processes for Study Delivery are executed through the development of study reports tools, facilitation of the study delivery system and maintenance of the system. As an expert, ensures delivery of a centrally managed study management service across clinical studies from start up to reporting Serve as main contact and works closely with the Document Management group until the Clinical Study Report is finalised Initiates and maintains production of study documents, ensuring template and version compliance Creates or imports clinical-regulatory documents into the Global Electronic Library according to the Global Document List Interfaces with Data Management Centre or Data Management Enablement representatives to facilitate the delivery of study related documents Manages and coordinates tracking of study materials and equipment Monitors administrative tasks during the study process, audits and regulatory inspections, according to company policies Acts as a technical owner within Patient Safety with a deep understanding of processes and internal regulations Keeps own knowledge of best practices and new relevant developments up to date Liaises with compliance team members to improve regulatory processes within the team Identifies opportunities to improve the methodology and provide practical solutions for clinical development Typical People Management Responsibility (direct / indirect reports): Approximate number of people managed in total (all levels) - None Education, Qualifications, Skills and Experience: Essential: Bachelor s degree in relevant discipline; Experience of Study Management within a pharmaceutical or clinical background; Knowledge of relevant legislation and new developments in the area of Clinical Development and Study Management Desirable: Advanced degree within the field; Professional certification; Understanding of multiple aspects within Study Management Key Relationship to reach solutions: Internal (to AZ or team): Study management function; Other AstraZeneca employees External (to AZ): External service providers and regulatory bodies

New Business Development Critical actions Assist in BD deal sourcing and work with cross functional teams on business case preparation and internal approvals Support Transaction Lead in discussions, negotiations and contract execution Manage request for proposal process and assist in identification and shortlisting of partners Measures (QQA) On-time launches for new deals BD deals with existing partners Drive partner business Ensure smooth integration of new partnerships under Alliances function Work with CFT - Medical/Ops/Regulatory etc. to proactively problem solve issues faced by the partners Project manage new launches by partners Prepare and drive partner business estimates and budgets in line with India Acceleration Plan Evaluate partner performance against commitments Look for extension of partnerships with existing partners Measures (QQA) Thoroughness of budgeting process and accuracy of the estimates Monthly achievements against the budget On-time new launches Manage internal and external stakeholders and communication on partner business Plan regular updated to relevant stakeholders on partner business performance Update monthly trackers per agreed timelines Work with the cross functional team to resolve issues Manage day to day communication with the partners with active problem solving and project management therein Measures (QQA) Effective communication to relevant stakeholders Maintaining timelines Documentation of the alliance management meetings and decisions Education, Qualifications, Skills and Experience Essential Graduate in technology and MBA from a premier B-school 8-10 years of overall experience Experience in Business Development, M&A, Technology Licensing, Alliance management, key account management or Management Consulting Strong Financial Modelling Skills Strong communication and team collaboration skills Ability to work drive conversations with senior stakeholders Experience in Pharma industry Ability to coordinate across Organization and Functions Strong connects internally and externally to support the Business Development efforts Desirable Experience in Pharma industry Ability to coordinate across Organization and Functions Strong connects internally and externally to support the Business Development efforts

Accountabilities: Manage implementation, upgrade, and support of Oracle Argus Safety System or other Safety solutions and associated interfaces/integrations. Participate in technical workstreams (Configuration/Data Migration/Reporting/Upgrade) and provide progress reports, proposals, requirements documentation, and presentations. Act as Oracle Argus SME, supporting technical issues associated with Oracle Argus Safety suite and related interfaces. Deliver project and customer success by meeting deadlines, managing expectations, and delivering high-quality solutions. Guide the team on critical issues or enhancements. Participate in design, build, and configure applications, acting as the main point of contact. Essential Skills/Experience: Overall IT experience of at least 10 years, with a minimum of 8 years in implementation/upgrade/support of Oracle Argus Safety. Prior experience in Oracle Argus managed services team and at least a couple of implementation/upgrade projects involving configuration/validation/data migration. Experience in configuring reporting destinations and rules with advanced conditions. Must have implemented continuous improvements. Must have trained and mentored junior members. Experienced in working with people from different geographies (e.g., USA, Europe). Experience in latest PV regulations by EMA, FDA, MHRA, and other regulatory agencies. Experience in PMDA regulations and working with Japan stakeholders. Experience in Regulatory Standards like 21 CFR Part 11, ICH, GxP. Solid experience in SQL, PL/SQL.

Introduction to role: Are you ready to lead the charge in transforming patient platforms and associated technologies As the Director of Commercial IT - Platform Engineering, youll be at the forefront of innovation, overseeing the end-to-end ownership and accountability of solutioning, design, development, execution, and operational management of production. Dive into technologies like Salesforce Communities, Health Cloud, AgentForce, Einstein, Salesforce Voice over AWS, and AppExchange implementations. Collaborate across engineering roles, testing capabilities, and business units while working closely with third-party suppliers to drive success. Accountabilities: Maintain deep working knowledge ofplatforms / products / infrastructurealigned with our global estate (US, ROW: LATAM, AsiaPAC, ANZ, Europe & Middle East) Lead build, test, and deployment activities for assigned platform and IT product initiatives Serve as the voice of technical expertise to peers and 3rd party development suppliers ensuring alignment to AZ IT and Commercial IT standards Oversee platform engineering resources to validate business and functional requirements Act as an internal consultant on key assigned platforms and technologies for IT and business partners Evaluate newtechnologies/applicationfeatures and recommend strategic roadmaps through prototyping Refine business requirements, set priorities, resolve issues, and deliver innovative solutions Collaborate with regional solution architects and capability teams to co-create functionalities with strategic markets Demonstrate understanding of AstraZeneca s application development processes - handle CI/CD pipelines and DevOps WOW Lead, mentor, and coach the AZ Application Development team globally to enhance throughput and quality Drive alignment with cyber security standard processes ensuring platform security Continuous Improvement and Innovation: Partner with Platform Success Lead(s) on continuous improvement opportunities within platform/product backlogs Identify new hardware/software technologies for specialized business needs Identify process issues and implement changes to improve IT efficiency Essential Skills/Experience: Understanding of the Salesforce technology stack - Salesforce Health Cloud, Salesforce Voice, Salesforce Communities mandatory Understanding and use integration patterns - experience designing, implementing MuleSoft mandatory Consistent record of crafting and operating critical applications Experience working with and influencing business and BA s around Salesforce architecture and designs Experience supporting and guiding development teams Expertise in application design patterns and processes Prior experience in an Information Services/Information Technology environment with good eye for business including SaaS & professional services contract management Expertise in Continuous Integration and Deployment methods delivered as part of an agile team Minimum bachelors degree and engineering experience Desirable Skills/Experience: Einstein 1, AgentForce, and Voice AI experience

Key focus areas currently are: Omnichannel and digital marketing for patients and HCPs E-commerce and consumerization Internal innovation External innovation with partners and start-up ecosystems Automation and simplification, leveraging artificial intelligence Analytics, insights, and data governance Support and implementation of business systems for office and field operations Role Overview: The Digital Solutions Delivery Director is responsible for empowering the field force, sale team and supporting internal (non-sales) functions in driving efficiency and productivity at scale. This role demands a collaborative and proactive approach to working with internal and external stakeholders to understand Indias business priorities and challenges and to deliver effective solutions. Success in this role requires the following skills: Comprehensive Business Analysis skill Project and program management Page 2 of 3 Strong written and verbal communication Collaboration across functions and geographies Stakeholder management Solution design Risk management Change Management Assertive while maintaining calm and composed demeanour A continuous learning mindset to adapt to the evolving technology landscape Core Accountabilities: Enable and empower the field force, sales team and supporting functions digitally, driving significant efficiency and productivity. Engage with stakeholders to understand business priorities, proactively identifying digitalization opportunities. Lead projects and programs with precision, managing risks and dependencies, ensuring timely delivery, budget adherence, and alignment with project/program objectives. Ensure that necessary internal/global governance and compliance standards are met and adhered to for every digital projects/programs/initiative Work closely with global cross-functional teams to understand global innovation, innovative pilots successfully deployed elsewhere in the globe, and bring these innovations to India Communicate project progress, updates, and risks to stakeholders, including executives and team members Foster a collaborative team environment, promoting effective teamwork and knowledge sharing. Use the bi-annual Pulse survey to evaluate and improve business and IT satisfaction Engage with tech start-ups through AstraZeneca s ACatalyst Network for potential collaborations in India. Essential Skills/Experience Relevant technical degree or equivalent (BTech/MTech with MBA) with strong academic performance. Understanding of the pharmaceutical/healthcare domain. Proven leadership in global organizations with complex, diverse environments. Expertise in relationship-building with senior internal customers and suppliers. Technical proficiency in: o Salesforce CRM (Health Cloud, Einstein) o Market Tech o Digital Health o Power BI o Application of AI and GenAI o Understanding of Workday, Coupa, SAP Concur Page 3 of 3 Strong communication, facilitation, and relationship-building skills. Experience influencing solution directions and adopting standards using architecture strategies. Proven ability to inspire change and challenge conventional ideas. Experience managing relationships with business teams and third-party suppliers. Strategic, big-picture thinking with an understanding of long-term implications. Critical thinking skills, questioning assumptions, and evaluating evidence objectively. Openness to change, adaptable to new insights and circumstances, supporting innovation. Awareness of marketplace developments and their potential impact on AZ. Desirable Skills/Experience Current leadership role in the Pharma/Healthcare industry