Scientist - Rapid CAR-T Generation

Job Description

Role & responsibilities In the current role, the candidate will have to develop new cell therapy products and perform validations to take the product to the next stage. Extensive experience working with different types of immune cells and deep understanding of both innate and adaptive immune systems will be required. Previous experience in gene and/or cell therapy drug development teams will be preferred. Experience in design and delivery of genes using viral or non-viral transfer techniques. Design and construct of viral vectors using state-of-the-art molecular synthesis and cloning techniques. Experience in use of CRISPR/Cas9 or TALEN or other gene-editing tools Well-versed with different molecular biology techniques like cloning, sub-cloning, real-time and quantitative PCR, etc. Ability to multitask and contribute to multiple projects under demanding timelines while preserving integrity, accuracy, safety, and quality. The candidate should be proficient in verbal, written and presentation skills and previous experience in writing grants and research articles will be preferred. The candidate should have had experience in managing a team or working in a cross-functional group and interacting with clients/collaborators. The candidate needs to have leadership skills to gear a team towards excellence. Manage day to day activity of team members providing critical technical/scientific recommendations with effective trouble-shooting and innovative capabilities. The candidate should be able to effectively communicate and work closely in a highly matrixed team environment to advance companys cell therapy pipeline. The candidate will be expected to understand systems and processes pertaining to sterile practices, work ethics, safety, health, and environment. The candidate will have to be involved in preparation and participation during compliance monitoring inspections and regulatory agency interactions. The candidate must be involved in preparation and review of protocols, reports, regulatory documents, pertaining to program requirement. Competencies: Gene editing and molecular biology techniques Gene transfer Viral and non-viral methods for cell line generation Immunology/Immuno-oncology Genetics and Assays Preferred candidate profile Ph.D. (specialization in genetics and epigenetics related to Immunology/Immuno-oncology) with 1-2 years of experience in Gene Editing and Immuno-oncology and/or industry or M.Sc/M.Tech in Biotechnology with 8-9 years of experience in academia and/or industry