Scientist - ADC DMPK

Aurigene Oncology Limited. (a Dr. Reddy's Subsidiary)

5 - 10 years

10 - 17 Lacs

bengaluru

Posted:14 hours ago| Platform:

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Skills Required

adc dmpk bioanalysis drug discovery antibody drug conjugate pk-pd

Work Mode

Work from Office

Job Type

Full Time

Job Description

Role & responsibilities

M. Pharm (Pharmacology / Pharmaceutical Analysis) / M.Sc. (Biochemistry / Pharmaceutical Chemistry) with 5-10 years or Ph.D. with 2-5 years experience
Expertise in designing and execution of DMPK studies to support ADC as well as antibody programs
Extensive experience on quantification of antibodies, therapeutic protein, ADC and peptides using LC-MS/MS or MSD or ELISA.
Well versed with handling of BioPharma finder, Maxquant, Spectronaut and other relevant software
Leverage current and new techniques for function-based identification and selection of antibody-drug-conjugate (ADC), mAb lead drug candidates with the understanding of their DMPK properties, ensuring the safe and effective delivery of novel therapeutics.
Interpret DMPK data and provide insights to project teams.
Represent the group in internal and external meeting.
Maintain strong relationship with other departments to understand ADC challenges and propose solutions from target concept to IND stage
Responsible for preparation of relevant SOP, protocols, reports, etc. to support various regulatory and non-regulatory submission.

Strong understanding of various concepts of DMPK including PK-PD, tox and excellent communication skills, driving innovation, managing teams is added advantage

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