Apprentice Trainee - DMPK Aurigene Oncology Limited. (a Dr. Reddy's Subsidiary)

0.0 - 1.0 years

1 - 2 Lacs

bengaluru

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M. Pharm (Pharmacology / Pharmaceutical Analysis) / M.Sc. (Biochemistry / Pharmaceutical Chemistry / Analytical Chemistry) with 0 -1 years experience. Roles & Responsibilities: Strong in basics of DMPK domain and principles of chromatography as well as sample processing Planning and Execution of in-vivo preclinical pharmacokinetic studies, in-vivo tissue distribution & mass balance studies in rodents. Well verse with extraction techniques of molecules from various matrices like plasma/urine/tissues Conduct Bioanalysis of samples from in-vivo pharmacokinetic, tissue distribution studies, PK-PD & TK studies through LCMS/MS are added advantage Knowledge of Phoenix WinNolin software will be adde...

Posted 1 month ago

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Invitro Research Scientist AVE-Promagne Business Solutions

2.0 - 7.0 years

10 - 11 Lacs

Hyderabad

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Your key responsibilities will include conducting In Vitro ADME studies. This involves reading and understanding various in vitro ADME protocols, as well as performing in vitro stability experiments for new chemical entities in liver microsomes, plasma, and other relevant matrices. You will also conduct specific in vitro ADME experiments such as logP, logD, pKa measurements, CYP induction and inhibition assays, permeability determinations, CYP phenotyping, and solubility determinations in various cell lines. In addition to in vitro ADME studies, you will be involved in bioanalysis activities. This includes developing and validating LC-MS/MS and HPLC-UV/PDA methods, conducting bioanalytical Q...

Posted 2 months ago

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Pharmacokinetics Scientist Veeda CR

6 - 11 years

6 - 12 Lacs

Ahmedabad

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Role & responsibilities Core Responsibilities: Design and Analyze PK Studies Plan clinical PK studies synopsis and feasibility Analyze PK data using modeling and simulation tools (e.g., Phoenix WinNonlin, R software). Interpret PK parameters such as C_max, AUC, T_max, half-life, clearance, and volume of distribution. Support Drug Development Provide PK and statistical input in clinical development phase studies protocol Evaluate food effect, drug-drug interactions (DDIs), and bioavailability/bioequivalence studies and provide scientific inputs for study design & protocol preparation Support dose selection and optimization strategies for pivotal study design Regulatory Submissions Deep unders...

Posted 5 months ago

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