Invitro Bioanalytical Scientist Syngene International Limited

3.0 - 7.0 years

0 Lacs

telangana

On-site

As an In vitro Bioanalytical Scientist at Syngene, based in Hyderabad, you will be responsible for participating in sample processing for PK and ADME assays, as well as handling LCMS/MS. Your role will involve adapting to a dynamic team environment, processing various matrices samples for PK studies, optimizing test compounds manually and automated on LCMS/MS, and independently handling HPLC for UV-based sample analysis. Additionally, you will be expected to develop methods with the team lead, document lab notebooks online, and manage compounds effectively. You will need to demonstrate expertise in column selection, mobile phase selection, solvent preparations, and sample processing techniques such as protein precipitation, liquid-liquid extraction, and solid-phase extraction. It is essential to have experience in handling ADME assays and HPLC and LCMS/MS, with a minimum of 3-5 years of relevant experience. Moreover, you should be capable of developing and validating LC-MS based qualitative/quantitative methods, conducting internet-based literature searches, and interpreting Mass/UV Spectra. As a part of the Syngene team, it is mandatory to adhere to safety guidelines, procedures, and SOPs, ensuring the safety of yourself, teams, and the lab/plant at all times. You must also complete all assigned mandatory trainings related to data integrity, health, and safety measures promptly. Furthermore, you will be expected to comply with Syngene's quality standards, hold yourself and your teams accountable for safety goals, and review safety metrics periodically. Syngene values excellence, integrity, and professionalism, and expects all employees to consistently demonstrate alignment with these core values. As a leader at Syngene, you will champion effective Environment, Occupational Health, Safety, and Sustainability (EHSS) practices, foster a corporate culture promoting an EHSS mindset, and uphold the highest standards of quality, integrity, and compliance. The ideal candidate for this role should possess a M. Pharm in Pharmaceutical Sciences or Pharmaceutical Analysis with a passion for LC/MS related bioanalysis. You should have a general understanding of drug metabolism and pharmacokinetics, be able to deliver scientific presentations, and write official project reports. Additionally, you should ensure preventative maintenance and calibration schedules of HPLC and mass spec by coordinating with vendors and support staff. Syngene is an equal opportunity employer, committed to providing integrated scientific services from early discovery to commercial supply, with safety as a top priority in all aspects of operations.,

Posted 6 days ago

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Senior Research Scientist DMPK Krish Biotech Research

2.0 - 6.0 years

0 Lacs

kolkata, west bengal

On-site

You will be responsible for providing drug metabolism and pharmacokinetic support for discovery programs. Your main duties will include monitoring Pharmacokinetics studies, supporting bioanalysis, and offering pre-clinical ADME lead optimization support to small molecule Drug Discovery programs across various therapeutic areas. You will be working as a DMPK subject matter lead in multidisciplinary/cross-functional teams to understand the Chemical Structure ADME relationships and design appropriate strategies to enhance the Drug like Properties of the New Chemical Entities. To be successful in this role, you should have 2-5 years of experience in GLP with either an M.Sc. or Ph.D. degree. You should possess expertise in Bioanalysis using LC-MS/MS in both GLP and non-GLP environments. Additionally, you should be capable of leading projects as a DMPK representative, quantifying small molecules using LC-MS/MS, and conducting metabolite identification work on High-resolution mass spectrometry. Qualifications required for this position include an M. Pharm (Pharmacology / Pharmaceutical Analysis) or an M.Sc. (Biochemistry / Pharmaceutical Chemistry).,

Posted 1 week ago

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