Chemist - Oligonucleotide

At Lilly, you will be part of a global healthcare leader headquartered in Indianapolis, Indiana, united in the mission to make life better for people worldwide. As part of our team of 45,000 employees, you will work towards discovering and delivering life-changing medicines, advancing disease understanding and management, and contributing to communities through philanthropy and volunteerism. Putting people first and giving your best effort to your work are values we uphold. We are seeking individuals who are dedicated to improving lives globally. In the RNA Therapeutics team, we are focused on developing expertise in oligonucleotide-based therapeutics and innovative delivery methods with the potential for significant efficacy breakthroughs. Operating as a biotech-like entity within Lilly, our diverse and agile team is in pursuit of an engaged and independent team member to drive impactful contributions to preclinical drug discovery efforts. We welcome applications from both experienced oligonucleotide laboratory chemists and small molecule chemists looking to transition to oligonucleotide chemistry. Join our dynamic and interdisciplinary team as we explore novel RNA/oligonucleotide-based medicines with the potential to cure diseases. As a Chemist specializing in Oligonucleotide Chemistry at Lilly, you will leverage your technical expertise to support core capabilities and contribute to the discovery and development of RNA-based clinical candidates, demonstrating an innovative approach towards drug discovery to enhance lives globally. Your responsibilities will include synthesizing, purifying, and analyzing highly modified oligonucleotides/conjugates and small molecules to drive projects forward efficiently, leading proactive safety practices in the laboratory, independently troubleshooting synthetic challenges, maintaining a productive laboratory workspace, collaborating with team members from various scientific backgrounds, interpreting and communicating structure-activity relationships, staying updated with relevant scientific literature, and documenting experimental procedures accurately. Basic qualifications for this role include a Master's degree in Chemistry or a related field, or a Bachelor's degree with 1-2 years of experience in Chemistry or a related field with exposure to synthetic organic and/or oligonucleotide chemistry. Additional skills and preferences include experience in oligonucleotide synthesis, small molecule organic synthesis, optimization of purification protocols, bioconjugation chemistry, analytical and physiochemical characterization of biomaterials, excellent record-keeping and communication skills, and a collaborative and execution-focused mindset. At Lilly, we are committed to fostering an inclusive workplace that supports individuals with disabilities and offers equal opportunities for all applicants. Our employee resource groups provide strong support networks and are open to all employees, promoting diversity and inclusion across our organization. The anticipated compensation for this position ranges from $63,000 to $162,800, depending on education, experience, skills, and geographic location. Full-time equivalent employees will also be eligible for a company bonus and a comprehensive benefit program, including healthcare, retirement, vacation benefits, and well-being initiatives. Lilly reserves the right to adjust its compensation and benefit programs as needed, in alignment with its compensation practices and guidelines. Join us at Lilly and be part of a team dedicated to making a positive impact on the lives of people worldwide.,