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6.0 years
0 Lacs
Chennai, Tamil Nadu, India
On-site
Job Title: Senior Bioinformatician GCL: D2 Introduction to role Are you ready to tackle some of the most challenging informatics problems in the drug discovery clinical trial phase? Join us as a Senior Bioinformatician and be part of a team that is redefining healthcare. Your work will directly impact millions of patients by advancing the standard of drug discovery through data processing, analysis, and algorithm development. Collaborate with informaticians, data scientists, and engineers to deliver ground breaking solutions that drive scientific insights and improve the quality of candidate drugs. Are you up for the challenge? Accountabilities Collaborate with scientific colleagues across AstraZeneca to ensure informatics and advanced analytics solutions meet R&D needs. Develop and deliver informatics solutions using agile methodologies, including pipelining approaches and algorithm development. Contribute to multi-omics drug projects with downstream analysis and data analytics. Create, benchmark, and deploy scalable data workflows for genome assembly, variant calling, annotation, and more. Implement CI/CD practices for pipeline development across cloud-based and HPC environments. Apply cloud computing platforms like AWS for pipeline execution and data storage. Explore opportunities to apply AI & ML in informatics. Engage with external peers and software providers to apply the latest methods to business problems. Work closely with data scientists and platform teams to deliver scientific insights. Collaborate with informatics colleagues in our Global Innovation and Technology Centre. Essential Skills/Experience Masters/PhD (or equivalent) in Bioinformatics, Computational Biology, AI/ML, Genomics, Systems Biology, Biomedical Informatics, or related field with a demonstrable record of informatics and Image analysis delivery in a biopharmaceutical setting. Strong coding and software engineering skills such as Python, R, Scripting, Nextflow. Over 6 years of experience in Image analysis/bioinformatics, with a focus on Image/NGS data analysis and Nextflow (DSL2) pipeline development. Proficiency in cloud platforms preferably AWS (e.g. S3, EC2, Batch, EBS, EFS etc) and containerization tools (Docker, Singularity). Experience with workflow management tools and CI/CD practices in Image analysis and bioinformatics (Git, GitHub, GitLab), HPC in AWS. Experience in working with any multi-omics analysis (Transcriptomics, single cell and CRISPR etc ) or Image data (DICOM, WSI etc) analysis. Experience working with any Omics tools and databases such as NCBI, PubMED, UCSC genome databrowser, bedtools, samtools, Picard or imaging relevant tools such as CellProfiler, HALO, VisioPharm particularly in digital pathology and biomarker research. Strong communication skills, with the ability to collaborate effectively with team members and partners to achieve objectives. Desirable Skills/Experience Experience in Omics or Imaging data analysis in a Biopharmaceutical setting. Knowledge of Dockers, Kubernetes for container orchestration. Experience with other workflow management systems, such as (e.g. Apache Airflow, Nextflow, Cromwell, AWS StepFunctions). Familiarity with web-based bioinformatics tools (e.g., RShiny, Jupyter). Experience with working in GxP-validated environments. Experience administering and optimising a HPC job scheduler (e.g. SLURM). Experience with configuration automation and infrastructure as code (e.g. Ansible, Hashicorp Terraform, AWS CloudFormation, Amazon Cloud Developer Kit). Experience deploying infrastructure and code to public cloud, especially AWS. When we put unexpected teams in the same room, we unleash bold thinking with the power to inspire life-changing medicines. In-person working gives us the platform we need to connect, work at pace and challenge perceptions. That's why we work, on average, a minimum of three days per week from the office. But that doesn't mean we're not flexible. We balance the expectation of being in the office while respecting individual flexibility. Join us in our unique and ambitious world. At AstraZeneca, we are driven by a shared purpose to push the boundaries of science and develop life-changing medicines. Our innovative approach combines ground breaking science with leading digital technology platforms to empower our teams to perform at their best. We foster an environment where you can explore new solutions and experiment with groundbreaking technology. With countless opportunities for learning and growth, you'll be part of a diverse team that works multi-functionally to make a meaningful impact on patients' lives. Ready to make a difference? Apply now to join our team as a Senior Bioinformatician! Date Posted 02-Jul-2025 Closing Date 30-Jul-2025 AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorization and employment eligibility verification requirements.
Posted 1 week ago
1.0 - 3.0 years
3 - 5 Lacs
Hyderabad
Work from Office
Sr Associate Scientific Business Analyst Biological Studies What you will do This role involves working closely with Amgen Research partners and Technology peers to ensure that the technology/ data needs for drug discovery research are translated into technical requirements for solution implementation. The role maximises scientific domain and business process expertise to detail product requirements as epics and user stories, along with supporting artifacts like business process maps, use cases, and test plans for the software development teams. This enables the delivery team to estimate, plan, and commit to delivery with high confidence and identify test cases and scenarios to ensure the quality and performance of IT Systems. You will join a multi-functional team of scientists and software professionals that enables technology and data capabilities to evaluate drug candidates and assess their abilities to affect the biology of drug targets. This team implements scientific software platforms for different Research imaging techniques such as Digital Pathology, High Content Screening (HCS), cell imaging, cryo-EM, etc. You will implement and manage imaging capabilities across the research informatics ecosystem, and provide technical support, training, and infrastructure management, and ensure it meets the needs of our Amgen Research community. Roles & Responsibilities: Function as a Scientific Business Systems Analyst within a Scaled Agile Framework (SAFe) product team Serve as a liaison between global Research Informatics functional areas and global research scientists, prioritizing their needs and expectations Manage a suite of custom internal platforms, commercial off-the-shelf (COTS) software, and systems integrations Lead the technology ecosystem for in vivo study data management and ensure that the platform meets their requirements for data analysis and data integrity Translate complex scientific and technological needs into clear, actionable requirements for development teams Develop and maintain a product roadmap that clearly outlines the planned features and enhancements, timelines, and landmarks Identify and manage risks associated with the systems, including technological risks, scientific validation, and user acceptance Develop documentations, communication plans and training plans for end users Ensure scientific data operations are scoped into building Research-wide Artificial Intelligence/Machine Learning capabilities Ensure operational excellence, cybersecurity and compliance. Collaborate with geographically dispersed teams, including those in the US and other international locations. Foster a culture of collaboration, innovation, and continuous improvement. What we expect of you We are all different, yet we all use our unique contributions to serve patients. Basic Qualifications: Masters degree with 1 - 3 years of experience in Life Sciences, Computer Science, IT, Computational Chemistry/Cheminformatics, Computational Biology/Bioinformatics or related field, OR Bachelors degree with 3 - 5years of experience in Life Sciences, Computer Science, IT, Computational Chemistry/Cheminformatics, Computational Biology/Bioinformatics or related field, OR Diploma with 7 - 9 years of experience in Life Sciences, Computer Science, IT, Computational Chemistry/Cheminformatics, Computational Biology/ Bioinformatics or related field Functional Skills: Must-Have Skills: 3+ years of experience in designing and supporting Research imaging platforms. Demonstrated expertise in a scientific domain area and related technology needs Excellent problem-solving skills and a passion for tackling complex challenges in drug discovery with technology and data Experience with writing user requirements and acceptance criteria in agile project management systems such as JIRA Experience with Proscia Concentriq, Deciphex Patholytix, HALO, Visiopharm, Revvity Signals Image Artist, Imaris, PSILO or similar imaging platforms Preferred Qualifications: Experience with Agile software development methodologies (Scrum) Experience performing or enabling image analysis from microscopes Ability to communicate technical or complex subject matters in business terms Knowledge of business analysis standard processes, DevOps, Continuous Integration, and Continuous Delivery methodology Experience with cloud (e.g. AWS) and on-premise infrastructure Experience designing and supporting scientific software platforms in biopharma Professional Certifications: SAFe for Teams certification (preferred) Soft Skills: Able to work under minimal supervision Excellent analytical and gap/fit assessment skills Strong verbal and written communication skills Ability to work effectively with global, virtual teams High degree of initiative and self-motivation Ability to manage multiple priorities successfully Team-oriented, with a focus on achieving team goals Strong presentation and public speaking skills
Posted 2 months ago
1.0 years
0 Lacs
Hyderabad, Telangana, India
On-site
Join Amgen’s Mission of Serving Patients At Amgen, if you feel like you’re part of something bigger, it’s because you are. Our shared mission—to serve patients living with serious illnesses—drives all that we do. Since 1980, we’ve helped pioneer the world of biotech in our fight against the world’s toughest diseases. With our focus on four therapeutic areas –Oncology, Inflammation, General Medicine, and Rare Disease– we reach millions of patients each year. As a member of the Amgen team, you’ll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives. Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, you’ll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career. Sr Associate Scientific Business Analyst – Biological Studies What You Will Do This role involves working closely with Amgen Research partners and Technology peers to ensure that the technology/ data needs for drug discovery research are translated into technical requirements for solution implementation. The role maximises scientific domain and business process expertise to detail product requirements as epics and user stories, along with supporting artifacts like business process maps, use cases, and test plans for the software development teams. This enables the delivery team to estimate, plan, and commit to delivery with high confidence and identify test cases and scenarios to ensure the quality and performance of IT Systems. You will join a multi-functional team of scientists and software professionals that enables technology and data capabilities to evaluate drug candidates and assess their abilities to affect the biology of drug targets. This team implements scientific software platforms for different Research imaging techniques such as Digital Pathology, High Content Screening (HCS), cell imaging, cryo-EM, etc. You will implement and manage imaging capabilities across the research informatics ecosystem, and provide technical support, training, and infrastructure management, and ensure it meets the needs of our Amgen Research community. Roles & Responsibilities: Function as a Scientific Business Systems Analyst within a Scaled Agile Framework (SAFe) product team Serve as a liaison between global Research Informatics functional areas and global research scientists, prioritizing their needs and expectations Manage a suite of custom internal platforms, commercial off-the-shelf (COTS) software, and systems integrations Lead the technology ecosystem for in vivo study data management and ensure that the platform meets their requirements for data analysis and data integrity Translate complex scientific and technological needs into clear, actionable requirements for development teams Develop and maintain a product roadmap that clearly outlines the planned features and enhancements, timelines, and landmarks Identify and manage risks associated with the systems, including technological risks, scientific validation, and user acceptance Develop documentations, communication plans and training plans for end users Ensure scientific data operations are scoped into building Research-wide Artificial Intelligence/Machine Learning capabilities Ensure operational excellence, cybersecurity and compliance. Collaborate with geographically dispersed teams, including those in the US and other international locations. Foster a culture of collaboration, innovation, and continuous improvement. What We Expect Of You We are all different, yet we all use our unique contributions to serve patients. Basic Qualifications: Master’s degree with 1 - 3 years of experience in Life Sciences, Computer Science, IT, Computational Chemistry/Cheminformatics, Computational Biology/Bioinformatics or related field, OR Bachelor’s degree with 3 - 5years of experience in Life Sciences, Computer Science, IT, Computational Chemistry/Cheminformatics, Computational Biology/Bioinformatics or related field, OR Diploma with 7 - 9 years of experience in Life Sciences, Computer Science, IT, Computational Chemistry/Cheminformatics, Computational Biology/ Bioinformatics or related field Functional Skills: Must-Have Skills: 3+ years of experience in designing and supporting Research imaging platforms. Demonstrated expertise in a scientific domain area and related technology needs Excellent problem-solving skills and a passion for tackling complex challenges in drug discovery with technology and data Experience with writing user requirements and acceptance criteria in agile project management systems such as JIRA Experience with Proscia Concentriq, Deciphex Patholytix, HALO, Visiopharm, Revvity Signals Image Artist, Imaris, PSILO or similar imaging platforms Preferred Qualifications: Experience with Agile software development methodologies (Scrum) Experience performing or enabling image analysis from microscopes Ability to communicate technical or complex subject matters in business terms Knowledge of business analysis standard processes, DevOps, Continuous Integration, and Continuous Delivery methodology Experience with cloud (e.g. AWS) and on-premise infrastructure Experience designing and supporting scientific software platforms in biopharma Professional Certifications: SAFe for Teams certification (preferred) Soft Skills: Able to work under minimal supervision Excellent analytical and gap/fit assessment skills Strong verbal and written communication skills Ability to work effectively with global, virtual teams High degree of initiative and self-motivation Ability to manage multiple priorities successfully Team-oriented, with a focus on achieving team goals Strong presentation and public speaking skills What You Can Expect Of Us As we work to develop treatments that take care of others, we also work to care for your professional and personal growth and well-being. From our competitive benefits to our collaborative culture, we’ll support your journey every step of the way. In addition to the base salary, Amgen offers competitive and comprehensive Total Rewards Plans that are aligned with local industry standards. Apply now and make a lasting impact with the Amgen team. careers.amgen.com As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients. Together, we compete in the fight against serious disease. Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or any other basis protected by applicable law. We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation. Show more Show less
Posted 2 months ago
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