4 Synthetic Methods Jobs

Scientist med chem: 2 5 years To Synthesize and characterize novel NCEs as per client specifications, in an efficient and independent manner. To have broad knowledge of modern organic chemistry and synthetic methods: heterocyclic chemistry, metal catalysed reactions, handling air/moisture sensitive reagents, hydrogenations, carrying out multi-step synthesis etc. To work with a wide range of techniques in synthesis and purification (Chromatographic methods including smooth knowledge of MPLCs), and spectroscopic characterization of novel compounds (NMR, LCMS, HPLC, IR etc.). Up to date maintenance of Lab Note Books, as per client specifications and guidelines. Generation of final reports, powerpoint presentations and other scientific documents by using the chemdraw as needed. Should be able to scout new / alternate schemes & know the use of scifinder, reaxys etc. Understanding of systems and process pertaining to safety, health and environment. Follow the EHS guidelines, as per zero tolerance policy. Show more Show less

Position Scientist Medicinal Chemistry (CRO) Location Hyderabad/Bangalore Desired Profile M.Sc. (Organic Chemistry/Chemistry) with 3-8 years Job Description, Key Skills And Competencies To synthesize, and characterize novel target molecules as per client specifications, in an efficient and independent manner. To have broad knowledge of modern organic chemistry and synthetic methods: heterocyclic chemistry, metal catalysed reactions, handling air/moisture sensitive reagents, hydrogenations, carrying out multi-step synthesis etc.. Hands-on experience with a wide range of techniques in synthesis and purification (Chromatographic methods including smooth knowledge of MPLCs), and spectroscopic characterization of novel compounds (NMR, LCMS, HPLC, IR etc.). Ability to think outside the box and independently solve synthetic problems. Troubleshooting for the whole team and being able to take quick and decisive actions (for PhD candidates and/or lab leaders). Maximize the productivity of the group and provide intellectual input to the department. Ability to manage a small team of 3-4 chemists, in addition to his/her individual work (for lab leaders/PhDs). Interaction with the clients and smooth communication of project goals/results during the weekly TCs/VCs (for lab leaders/PhDs). Up to date maintenance of Lab Note Books, as per client guidelines. Generation of final reports and other scientific documents, as needed. Understanding of systems and process pertaining to safety, health and environment. Follow the EHS guidelines, as per zero tolerance policy. Competencies Good Communication Skills Interpersonal Skills Team Player Show more Show less

As a leading Chemistry Contract Research, Development & Contract manufacturing organization (CDMO/CMO), Mithros offers comprehensive chemistry services to the Pharmaceutical Industry, material science industry, polymer science industry, and Research organizations. With customer-oriented and flexible business models such as FFS, FTE, and risk-shared arrangements, Mithros caters to a wide range of applications. We are currently seeking a highly motivated and research-oriented individual with strong problem-solving skills to join our team. The selected candidate will play a key role in leading and supporting process research and scale-up activities. Responsibilities include commercializing products through the development or modification of protocols that are safe, cost-effective, environmentally friendly, scalable, and efficient. Knowledge of plant operations, tech transfer, reactor mapping, troubleshooting, and project proposals is essential for this role. Key Responsibilities: - Lead and manage the process research team and scale-up scientists to deliver high-quality compounds within strict timelines. - Develop synthetic plans, design and conduct experiments for large-scale production. - Utilize analytical tools to monitor reaction processes effectively. - Optimize the use of project resources by monitoring, measuring, and reporting on scientific issues and achievements. - Troubleshoot processes during development and production phases. - Enhance existing process protocols by improving cost-efficiency, reliability, purity, and safety. - Resolve technical and scientific issues affecting material delivery by collaborating with internal teams and partners. - Assist in writing project proposals and reports. - Willingness to relocate to Europe if required. Candidate Requirements: - PhD in Organic Chemistry with a minimum of 8 years of experience in process development and scale-up, preferably in CRO/CDMO settings. - Strong knowledge of classical and modern synthetic methods in organic chemistry. - Ability to work independently, lead teams, and motivate colleagues. - Strong conceptual, analytical, problem-solving, and organizational skills. - Capacity to thrive in a fast-paced team environment, manage deadlines, and prioritize tasks effectively. - Excellent interpersonal and communication skills, with a proven ability to collaborate within a team. - Ability to manage multiple projects simultaneously and adapt to changing priorities. - Proficiency in compiling results data, creating presentations, and sharing outcomes through effective communication and online meetings is a plus.,

As a Medicinal Chemist, you will be instrumental in the development, synthesis, and enhancement of innovative drug candidates. Your role will call for a blend of scientific proficiency, analytical thinking, and practical laboratory experience to lead drug discovery projects from initial identification to advanced optimization and preclinical phases. Working in close collaboration with diverse teams, you will contribute towards the creation of cutting-edge therapeutics to meet the gaps in medical treatment. Your primary responsibilities will include: - Designing and synthesizing novel small molecules aimed at specific disease targets. - Strategizing and executing pioneering methodologies in drug discovery autonomously or in partnership. - Leveraging Structure-Activity Relationships (SAR) and Structure-Property Relationships (SPR) to refine efficacy, specificity, and pharmacokinetic characteristics. - Engaging with computational chemists, biologists, and pharmacologists to prioritize new chemical entities for synthesis and evaluation. - Conducting comprehensive literature assessments to adopt novel synthetic strategies and technologies. - Participating in the development of patent applications, technical documents, and scientific publications. - Employing computational models to anticipate the performance of new drugs and facilitate the design of fresh compounds. - Keeping abreast of evolving trends in AI-driven drug discovery and advancements in medicinal chemistry. To qualify for this role, you should possess: - A Ph.D. in Organic Chemistry or a related discipline. - Extensive industry experience spanning 10-13 years within Life Sciences, R&D, CRO, biotech, or pharmaceutical sectors. - Profound expertise in synthetic organic chemistry, medicinal chemistry, and chemical biology. - Proficiency in contemporary synthetic techniques, purification methodologies, and analytical tools such as NMR, LC-MS, and HPLC. - Demonstrated achievements in lead optimization and preclinical drug discovery. - Familiarity with pharmaceutical industry standards and regulatory landscapes. - Knowledge of AI-driven drug discovery techniques would be advantageous. - Exceptional problem-solving abilities, scientific ingenuity, and a fervor for innovation. - Strong communication and teamwork skills to thrive in a multidisciplinary environment.,