Medicinal Chemist Alembic Pharmaceuticals Limited

10.0 - 14.0 years

0 Lacs

hyderabad, telangana

On-site

As a Medicinal Chemistry leader at Alembic, you will be at the forefront of driving the next wave of therapeutic innovation. Your role will involve shaping the future of drug discovery from India and bridging into the U.S. biotech ecosystem. Based in Hyderabad Genome Valley, you will work full-time and report to the Head of Drug Discovery at Alembic. You will be tasked with spearheading small-molecule and peptide drug discovery efforts, shaping and executing innovative strategies that drive programs from target identification to nominating clinical candidates. Alembic is seeking a visionary and accomplished leader with a track record of advancing compounds from early discovery to IND-enabling studies. The ideal candidate will possess deep expertise in medicinal chemistry, hands-on problem-solving skills, and preferably experience in computational chemistry or AI-enabled design. Your key responsibilities will include leading medicinal chemistry strategies for designing, synthesizing, and optimizing novel drug candidates. You will execute SAR strategies to enhance potency, selectivity, and overall drug-like properties, driving hit-to-lead and lead optimization efforts across multiple discovery programs. Additionally, you will incorporate AI-driven drug design and computational modeling into the medicinal chemistry workflow and manage external collaborations with CROs and academic partners. Furthermore, you will partner closely with various teams such as biology, pharmacology, DMPK, and analytical chemistry to integrate data and advance candidates efficiently. Your role will also involve analyzing experimental results, generating hypotheses, and making data-driven decisions to guide programs. Building and mentoring a team of medicinal chemists to foster scientific innovation and professional growth will also be a part of your responsibilities. To qualify for this role, you should hold a PhD in Organic or Medicinal Chemistry (or a related discipline) with over 10 years of industry experience in drug discovery. Demonstrated leadership in advancing small molecules or peptides into the clinic, deep expertise in synthetic chemistry, drug design, and SAR optimization are essential. Exposure to AI-based drug discovery, computational chemistry, or fragment-based design will be advantageous. Strong communication, leadership, and decision-making skills are also required. By joining Alembic, you will lead cutting-edge medicinal chemistry initiatives, collaborate with world-class scientists in an innovation-driven culture, play a central role in shaping Alembic's emerging therapeutic pipeline, and contribute to an organization committed to scientific rigor, global impact, and patient health. Alembic embraces diversity and is dedicated to building an inclusive team.,

Posted 1 month ago

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Lead - Medicinal Chemist Alembic Pharmaceuticals

10.0 - 15.0 years

20 - 30 Lacs

Shamirpet, Hyderabad

Work from Office

Role & responsibilities Lead medicinal chemistry strategies for the design, synthesis, and optimization of novel drug candidates. Execute SAR (Structure-Activity Relationship) strategies to improve potency, selectivity, and overall drug-like properties. Drive hit-to-lead and lead optimization efforts across multiple discovery programs. Incorporate AI-driven drug design and computational modeling into medicinal chemistry workflow. Manage external collaborations with CROs' and academic partners to scale compound synthesis and profiling. Partner closely with biology, pharmacology, DMPK, and analytical chemistry to integrate data and advance candidates efficiently Analyse experimental results, generate hypotheses, and make data-driven decisions to guide programs. Build and mentor a team of medicinal chemists, fostering scientific innovation and Professional growth. Remain hands-on in chemistry when needed, applying creativity and rigour to overcome key design challenges. Preferred candidate profile PhD in Organic or Medicinal Chemistry (or a related discipline) with 10+ years of industry experience in drug discovery. Demonstrated leadership in advancing small molecules or peptides into the clinic. Deep expertise in synthetic chemistry, drug design, and SAR optimization. Exposure to AI-based drug discovery, computational chemistry, or fragment-based design. Solid understanding of DMPK, pharmacology, and safety assessment in early development Familiarity with patent strategy and regulatory considerations for small-molecule therapeutics Proven ability to manage cross-functional projects and external partnerships Excellent communication, leadership, and decision-making skills

Posted 3 months ago

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