7 Protein Engineering Jobs

Are you passionate about advancing the frontiers of biologic therapies and eager to apply your expertise in protein engineering to real-world manufacturing challenges If so, a postdoctoral opportunity in the Sikes Lab at MIT may be the perfect next step in your research career. The Massachusetts Institute of Technology (MIT) is one of the world's premier research universities, renowned for its leadership in science, engineering, and technology. Located in Cambridge, Massachusetts, MIT fosters a collaborative and innovative academic environment where interdisciplinary research thrives. Its Chemical Engineering Department is globally recognized for excellence in both fundamental and applied research, offering unparalleled resources, mentorship, and connections to industry and academia. This postdoctoral position focuses on bioseparations in the context of manufacturing biologic therapies. Bioseparations play a crucial role in the purification and production of therapeutic proteins and biologics, which are increasingly important in treating various diseases. As the demand for biologic medicines rises, innovative bioseparation techniques are essential to ensure product quality, safety, and scalability. The research in this project aims to make significant contributions to the advancement of next-generation biologic manufacturing processes, impacting patient care and the biotechnology industry. The successful candidate will join Dr. Hadley Sikes" laboratory, known for its work in biomolecular engineering, applications of redox chemistry, clinical diagnostics, and molecular biotechnology. The project involves experimental work in protein engineering, emphasizing strong quantitative skills in engineering design, particularly in reaction kinetics and transport phenomena. The Sikes Lab provides a supportive environment that values both individual initiative and collaborative teamwork. Applicants suited for this postdoctoral role should have a strong background in protein engineering with hands-on experimental laboratory experience, expertise in engineering design including quantitative analysis of reaction kinetics and transport phenomena, excellent collaboration skills, and a genuine interest in biomolecular engineering, redox chemistry applications, clinical diagnostics, or molecular biotechnology. The ideal candidate will be driven, innovative, and eager to contribute to impactful research in the field of biologic therapy manufacturing. Interested candidates are encouraged to contact Dr. Hadley Sikes by sending a CV if they believe their skills and interests align with the position. Early contact is recommended as no specific application deadline has been mentioned. This postdoctoral opportunity at MIT offers a chance for researchers to advance their careers in bioseparations and biologic therapy manufacturing at a leading research institution. If you are interested in joining a collaborative and innovative team, do not hesitate to reach out with your CV. Stay connected with the latest advancements in your field by following similar postings and exploring opportunities for growth.,

Technoculture Research is re-imagining how the world measures health. We build micro-scale electrochemical laboratories that place lab-grade accuracy directly in the hands of clinicians, community health workers, and even patients at home. Our platform fuses microfabricated electrodes, novel surface chemistries, and microfluidics to run protein, nucleic-acid, and metabolite assays within minutes. By replacing costly optical detection with electron sensing, we slash instrument and per-test costs by roughly an order of magnitude, making precision diagnostics truly accessible. Our mission is clear: make diagnostics abundant so that every critical health decision is guided by immediate, affordable results, wherever care happens. Looking Ahead: Bio-Energy leveraging our strengths in electrochemistry, biotechnology, and process miniaturization, Technoculture Research is now expanding into bio-energy from green hydrogen and ammonia synthesis to sustainable liquid fuels. This enables us to apply our core science to one of the world's most urgent challenges: decarbonizing energy and chemicals. Internship Description We are looking for an enthusiastic and detail-oriented Enzyme Development Intern to support our R&D efforts in enzyme production, protein engineering, and hybrid enzymatic-electrochemical technologies. The ideal candidate will be eager to learn molecular biology techniques, assist with experimental design, and contribute to our enzyme optimization and characterization workflows. This internship offers a valuable hands-on opportunity in synthetic biology, diagnostics, and sustainable chemistry. Selected Interns Day-to-day Responsibilities Include - Assist in microbial expression of enzymes and purification protocols. - Support molecular cloning and plasmid construction workflows. - Conduct basic bioinformatic analysis such as protein sequence alignment and structure prediction. - Help set up and test enzyme activity assays, both in vitro and in cell-free formats. - Maintain detailed lab records, including protocols and experimental outcomes. - Collaborate with scientists working on CO reduction and bio-electrochemical systems. About Company: Technoculture Research is based in Bodhgaya, Bihar, India. We focus on developing modern technology relevant to many fields in our day-to-day lives, including construction, machinery, food, drugs, and agriculture. Our recent project focuses on developing and implementing novel methods for efficient water harvesting and artificial water recharge methods. One of our key objectives is to produce a platform capable of accurately predicting the hydrological conditions over an area to aid in the development and decision-making processes. We do research and development based on newly developed technologies. Our main focus is on inventing products for commercial and industrial use. We have a high-tech biotech lab for research and development on biomedical, biomechanical, and bioelectronics products. We do product development and design. We research novel and innovative ideas as well as cost-effective products for the next generation.,

You should be an individual with an MSc or MTech degree in Bioinformatics or Computational Chemistry, coupled with 2 to 4 years of experience in the field. Your responsibilities will include being an integral part of a team dedicated to accomplishing project goals successfully, encompassing both industrial and academic projects. It will be your duty to devise innovative project plans for each project under your supervision, and you should demonstrate proactive troubleshooting abilities to handle any experimental challenges that may arise. Your core skills should revolve around expertise in Modelling, Docking, and Molecular Dynamics simulation. Additionally, you should possess a foundational understanding or experience in protein structure, function, dynamics, and engineering. Proficiency in programming and scripting languages such as Fortran, C, C++, Perl, and Python is essential. Strong scientific writing skills are also required, enabling you to produce articles suitable for high-impact factor journals. You should be adept at explaining algorithms and refining them for enhanced outcomes. A collaborative mindset, dedication to team success, and the ability to work autonomously are crucial traits. Exceptional interpersonal and communication skills are highly valued in this role. Moreover, familiarity with tools like Gromacs, Auto dock, and Modeller would be advantageous. If you meet these qualifications and are excited about this opportunity, please send your profiles to Shilpa.ramdurg@quantumzyme.com.,

This senior level position is located in the Centre for Cancer Immunology at Southampton General Hospital, a newly constructed research building resulting from a significant fund-raising campaign. The centre, being the first dedicated cancer immunology centre in the UK, continues a 40-year history of pioneering immunology and cancer research at Southampton. From pioneering discovery science to applied research, preclinical modelling, and first-in-human clinical trials, the activities at this centre are comprehensive. The world-class facilities include state-of-the-art scientific laboratories and a clinical trials unit. This position is associated with the laboratory of Professors Sally Ward and Raimund Ober, focusing on protein engineering to develop novel antibody-based therapeutics. The interdisciplinary research program has led to approved therapeutics and is supported by major grants from Wellcome Trust, Cancer Research UK, and collaborating biopharma companies. The appointee will oversee in vitro and in vivo cellular assays, with a strong track record in analyzing the behavior of antibody or protein-based therapeutics. Responsibilities include managing research projects, supervising junior technicians, and training laboratory members in immunological and in vivo techniques. The appointee will work collaboratively within the group, contributing to research productivity. Professional development and career advancement opportunities are abundant and actively encouraged. The ideal candidate should have scientific knowledge equivalent to a Ph.D. level with 2-3 years of additional experience, expertise in immunological assays, flow cytometry, microscopy analyses, and project management skills. While experience in expressing and purifying recombinant proteins/antibodies is desirable, it is not essential. Relevant academic qualifications, work experience, and good IT skills are required. This position is open to non-UK/non-EU citizens as well. The initial term of this position in the Ward/Ober laboratory is two years, limited by the current grant support. For informal enquiries, contact Professor E. Sally Ward at e.s.ward@soton.ac.uk. The University of Southampton aims to create an inclusive working environment that fosters respect, equality of opportunity, and diversity. They encourage a flexible working approach and offer a generous holiday allowance along with additional university closure days to support staff and students. Applications should be submitted by 11.59 pm GMT on the closing date. For assistance, contact Recruitment on +44(0)2380 592750 or recruitment@soton.ac.uk quoting the job number.,

This senior level position is based in the Centre for Cancer Immunology at Southampton General Hospital, which is a newly constructed, dedicated research building resulting from a significant fund-raising campaign. The center is the first dedicated cancer immunology center in the UK, building on Southampton's 40-year history of pioneering immunology and cancer research. It spans activities from pioneering discovery science to applied research, preclinical modeling, and first-in-human clinical trials. You will work within the laboratory of Professors Sally Ward and Raimund Ober, contributing to an interdisciplinary research program focused on developing novel antibody-based therapeutics using protein engineering. The group's research is funded by major grants from organizations such as the Wellcome Trust and Cancer Research UK. You will oversee in vitro and in vivo cellular assays, with a strong background in analyzing the behavior of antibody or other protein-based therapeutics. In addition to leading research projects, you will play a supervisory role, responsible for guiding junior technicians and training laboratory members in immunological and in vivo techniques. The position requires teamwork and collaboration within the laboratory, spanning molecular and cellular analyses to studies in mouse models of disease. To be successful in this role, you should have scientific knowledge equivalent to a Ph.D. level, with 2-3 years of additional experience. Relevant academic qualifications, proven leadership skills, and good IT proficiency are essential. Professional development and career advancement opportunities are available, with support for pursuing them actively encouraged. As part of the Ward/Ober laboratory, this position is a key long-term role, initially limited to a two-year term based on current grant support. Non-UK/non-EU citizens are encouraged to apply. For more information, informal enquiries can be directed to Professor E. Sally Ward at e.s.ward@soton.ac.uk. The University of Southampton fosters an inclusive, respectful, and equal opportunity environment, where staff are encouraged to bring their whole selves to work. The university offers generous holiday allowances, university closure days, and supports flexible working approaches. If interested, please apply online by the closing date, quoting the job number. For assistance, contact Recruitment at +44(0)2380 592750 or recruitment@soton.ac.uk.,

Responsibilities: * Conduct formulation research & development. * Collaborate with R&D team on new product launches. * Develop protein-based food products. * Optimize food processing techniques. Food allowance Annual bonus

Design and execute MD simulations of proteins in various solvent environments Prepare protein structures, system setup, solvation, and equilibration Perform a comprehensive analysis of MD trajectories to extract meaningful dynamic insights Required Candidate profile Hands-on experience with molecular dynamics simulations Experience with GROMACS (topology generation, mdrun, analysis tools) or other MD packages (AMBER, NAMD, OpenMM)