8 Protein Characterization Jobs

The candidate would be developing various analytical method (such as CD, Fluorescence spectrscopy ,CE UH/HPLC etc..)for CQA to support bio similarity and analytical studies. Qualify method for biosimilarity and analytical studies. Responsible for performing biosimilarity, characterization and analytical studies for various molecules across lifecycle . Evaluation, interpretation and graphical representation of the measurement data as well as presentation of the results obtained from multiple experiments. Author technical documents such as MoA,MQR,SOP,study protocol and report.

Key Responsibilities: Develop mass spectrometry-based analytical methods for pivotal studies such as biosimilarity and comparability assessments Operate, maintain, and troubleshoot mass spectrometry instrumentation to ensure optimal performance Design and execute multiple assays for comprehensive characterization of protein-based therapeutics across various project stages Contribute to the design, development, and implementation of methods for critical quality attributes (CQA) and impurity characterization Analyze data, interpret experimental results, and draw conclusions from multi-stage analytical studies Prepare and author technical documentation including Standard Operating Procedures (S...

Role & responsibilities Perform Mass Spectrometry (LC-MS/MS) analysis for structural and physio-chemical characterization of peptides/proteins (Intact mass, Peptide mapping, Sequencing) Operate and maintain high-resolution mass spectrometer (Q-TOF/Orbitrap/Relevant Instruments) Support characterization studies for biologics - Insulin and Insulin Analogues, Therapeutic proteins and Biosimilars Ensure proper compliance in line with GLP norms Preferred candidate profile Proficient in advanced proteomic analysis methods. Proficient in impurity analysis, top-down and bottom up proteomics Experience of using various advanced structural characterization methods (CE, CD, DSC, DLS, IR, AUC) would be ...

Bring more to life. Are you ready to accelerate your potential and make a real difference within life sciences, diagnostics and biotechnology At Cytiva, one of Danaher's 15+ operating companies, our work saves livesand we're all united by a shared commitment to innovate for tangible impact. You'll thrive in a culture of belonging where you and your unique viewpoint matter. And by harnessing Danaher's system of continuous improvement, you help turn ideas into impact innovating at the speed of life. Working at Cytiva means being at the forefront of providing new solutions to transform human health. Our incredible customers undertake life-saving activities ranging from fundamental biological re...

As a professional in the field of biotechnology and biochemistry, you will have the following responsibilities: - **For Protein Characterization - Analytical:** - Hold an M.Sc. / M. Tech. in Biochemistry / Biotechnology with at least 5 years of industrial hands-on experience. - Demonstrate sound knowledge in analytical method development, validation, technology transfer activities, and scientific report writing skills. - **For Upstream Process Operations:** - Hold an M.Sc. / M. Tech. with Biotechnology with 1 to 3 years of experience or a Ph.D. / M. Tech. with more than 10 years of experience. - Capable of handling mammalian cell culture processes, microbial fermentation, and equipment such ...

Principal Scientist (Molecular Biology) Molecular Biology activities involved in making recombinant constructs for stable and transient gene expression like PCR amplification, restriction digestion, molecular cloning of genes, sequence confirmation, glycerol stock preparation, large scale endotoxin free DNA preparation. Analytical skills and activities related to protein estimation and characterization like CEDEX, ELISA, SDS/Western Blot, Octet and HPLC. Standard cell culture activity such as: Vial thaw, Subculturing, Transfection, single cell cloning, cryo-preservation, fed batch, Monoclonality assurance. Document and record maintenance like SOP/GM and data recording in eLN. Timely revision...

Key Responsibilities: Perform aseptic handling for various upstream operations. Prepare media and feeds for shake flask experiments and bioreactor batches. Handle shake flasks for clone selection, media optimization, and feed strategy development. Prepare and maintain bioreactors at different scales (1L, 5L, 20L). Execute upstream batches in small-scale and large-scale bioreactors. Conduct in-process sample analysis including cell count, viability, and metabolite levels (glucose, lactate, ammonia, glutamine, etc.). Draft and maintain Standard Operating Procedures (SOPs) for instruments and processes. Participate in shift duties for continuous batch monitoring and process support. Collaborate...

Hiring professionals with expertise in the analytical method development and characterization of biologic molecules. Hands-on experience with analytical techniques such as HPLC, UPLC, Capillary Electrophoresis, and Mass Spectrometry is required. Experience in method development, qualification, and transfer is highly desired. Guiding and mentoring juniors is a plus. Preferred candidate profile