Principal Scientist - Downstream Processing

Education and Experience :

• Minimum of M.Tech/M.S in Chemical Engineering/Biotechnology/Biochemistry/Biochemical Engineering and other related fields a must.
• Industrial Experience of 6-8 Years

Requirements:

A successful candidate for this position will display many of the following attributes:

• Knowledge of downstream process development, product purification, protein biochemistry, separation processes: filtration, TFF, Chromatography, extraction, enzymatic reactions, crystallization, lyophilization etc. and their underlying theory.
• Downstream processing of Mabs (monoclonal antibodies) is a must have.
• Hands-On Experience in handling the following equipment: GE AKTA Chromatography Systems, TFF Equipment, Centrifuge, Filtration systems, HPLCs.
• Understands statistics and can perform data analysis. Enthusiastic to build on their statistical skills.
• Passionate about developing scalable processes
• Adaptable to work in an agile, fast paced environment with competing priorities, evolving goals.
• Able to work within a team and complement strengths of other team members
• Experience with Empower CDS a plus
• Able to work independently, possess excellent communication skill, problem-solving skills.
• Able to work with cross-functional teams successfully and communicate technical findings.

Responsibilities:

In their role, the candidate will have the responsibility of:

• Individually contributing to the design, execution, analysis, documentation and archival of complex experiments related to downstream process development of biologics at lab, pilot and manufacturing scale.
• Supporting technology transfer from R&D to pilot plant and manufacturing.
• Participating actively in cross-functional meetings and communicate key findings.
• Participating actively in key regulatory filings.
• Supporting process characterization and validation of biologics.
• Maintaining a safe workplace by adhering to prevalent EHS and OSHA standards.
• Collaborate with QA, QC, Manufacturing and Regulatory functions in order to successfully deliver drugs to customers.
• Contributing to project planning, logistics.
• Providing support to other team members as per priority and requirement.
• Perform literature reviews and summarize relevant topics for the development of work streams.