2 Nmr Spectroscopy Jobs

Process Analytical Technology Expert POSITION PURPOSE: The PAT Expert will be instrumental in developing and implementing advanced process analytical technologies to enhance process development, optimization, and control at Process in R&D facility in Vapi. This role requires a solid background in Chemical Engineering, along with industrial experience in process monitoring and analytical tool development. The PAT Scientist will collaborate closely with cross-functional teams to drive innovation and facilitate data-driven (chemometrics) decision-making in support of chemical manufacturing initiatives. YOUR TASKS AND RESPONSIBILITIES: Development & Implementation: Design and implement PAT methodologies to support laboratory process development and scale-up activities and ensure implementation on the commercial scale. Process Monitoring & Control: Utilise real-time analytical techniques such as spectroscopy (NIR, MIR and Raman) and other sensor-based technologies like pH, conductivity, redox, turbidity etc. Data Analysis & Modelling : Employ statistical tools, chemometric modelling, and multivariate data analysis to derive insights from PAT data and gain understanding into reaction chemistry for safely upscaling the processes. Technology Integration : Collaborate with the PCT, electrical and IT teams to integrate PAT tools into lab-scale, pilot-scale, and manufacturing systems. Collaboration & Training: Co-ordinate with Quality and Manufacturing teams to ensure successful PAT implementation; provide training and support to internal stakeholders. Continuous Improvement: Identify new PAT opportunities and emerging technologies to enhance process efficiency and quality standards. KEY WORKING RELATIONS: Internal Crop Protection Innovation Team Pilot Plant Team CPI Production Team CPI Analytical team at Vapi External Coordinate with Various Vendors and Engineers for instrument installation/ maintenance activities WHO YOU ARE: Masters or Ph.D. in Chemical Engineering, or a related field. Industrial experience (4+ years with Ph.D., 8+ years with B.E.) in PAT development and implementation within the pharmaceutical or chemical industry. Proficient in in-line, on-line, and at-line PAT techniques, including Raman, MIR, and NIR spectroscopy. Knowledge of NMR and chromatography (HPLC, GC, LC-MS and GC-MS) based PAT tools will be advantageous. Hands-on experience with software tools for chemometrics and multivariate data analysis. Knowledge of process engineering for the effective transfer of technologies into production environments. Excellent problem-solving, communication, and project management skills. Ability to thrive in a dynamic, fast-paced, and collaborative environment. A scientifically curious mindset with a willingness to learn beyond core expertise. Willingness to work in shifts. SECURITY NOTE: We at PERSOLKELLY India or our representatives, do not ask job seekers for fees, personal banking information, or payments through unofficial channels. Official communications will only come from @persolkelly.com. Report any suspicious activity to Contactus_in@persolkelly.com. Click here to find out how you can safeguard yourself from job scams

Key Responsibilities: Strategic Actively imbibing the values and philosophy of PI Industries. Efficient contribution to the overall success of product innovation (PRI) through scientific contribution to objectives and targets being set by the leadership team. Fullfilling requirements and achieveing goals set by the Team Leader and Group Leader Working as a team member, contributing to the team objective with special focus on achiving and exceeding the set target. Development of individual & team strengths by attending trainings based on the regular feedback as an individual and as a team Operational Monitoring reaction masses using LCMS/GCMS. Execution of purity assessment and assay determination of samples using GC/HPLC/UFLC. Able to carry method development for challenging compounds through GC/GCMS/HPLC/UFLC Developing methods on Prep HPLC for purification/isolation of impure compounds. Elucidating and confirming structures using NMR, FTIR and LCMS/MS Ensure the scheduled performance of calibrations, Preventive maintenance and troubleshooting of core analytical instrument. Following the set instrument maintenance practices like periodic solvent changes, system flushing, etc. Assist the other team members in day to day activities like sample preparation, method developments, report generation and data management. Following safety practices with out fail. Financial Planning the activities with existing resources and infra structure. Suggesting the cost-effective areas to the Team Leader / Group Leader Developing methods to improve the environment safety and to reduce the cost. People Collaborate with team members and cross functional teams to meet research objectives. Develop and foster positive relationships with other teams and support groups to maximize cooperation and consequent benefit to objective delivery Should be able to work in multitasking environment Ensure team harmony through collaboration and active participation in all team discussion Apart from the above responibilities, specific responsibilities of Research scientists Note : The Associate would in any of the areas listed below based on the requirement and should have sufficient knowledge and expertise in the area alloted as listed below 1. HPLC/UFLC Candidate should be well versed with normal and reverse phase chromatography techniques. Able to optimize chromatographic methods Keen knowledge on low level analyte-impurities quantification by HPLC. 2. LCMS SQD & TQD Well versed with operations of one or more makes of LCMS-SQD & TQD instruments. Aware of basic principles related to mass spectrometry, sources, analysers and detectors. Hands on experience in analysis of compounds using LCMS instrument and releasing the mass confirmation reports. Keen knowledge on ppb / ppm level quantification of analytes from AI, formulations, various matrices like microsomes, soil, plant extracts by LCMSMS. Perform possible structural elucidation/Identification of degradants/metabolites/impurities using LCMS/MS 3. NMR Perform suitable 1D/2D NMR experiments based on the requirement and confirm one among proposed structures or propose a new structure. Manage the NMR activities viz, perform routine NMR (1D&2D) analysis, QNMR, cryogen replenishing. Keen knowledge of NMR technology & instrument maintenance. 4. Physchem assays Have hands on knowledge of various in vitro ADME/ physchem assays like solubility, LogP, pKa and in vitro Metabolic stability assay. Able to develop methods, check method compatibility for accuracy, precision, matrix effect and apply it further for the quantification of formulations, plant extracts, various matrices like soil, microsomes etc. Perform the microsomal stability experiments to determine half-life and Clint. Awareness about Met ID using various scans, fragmentation tree & HRMS will be an added advantage. Knowledge about sample preparation and analysis of photo stability and hydrolytic stability. 5. Prep-HPLC Able to develop a robust chromatographic method both at analytical and preparative scale, by designing cost effective methods for chiral and achiral molecules. Knowledge of chiral chromatography and isolation of enantiomers using preparative HPLC. Please share updated resume on e-mail id Shubhi.chandnani@piind.com