Desired Profile: DMLT/ B.Sc. in Medicsl Lab Technology/life sciences with 3 - 6 years of experience in Necropsy, tissue collection, preservation, tissue processing, tissue embedding and slide preparation. Role & responsibilities: Responsible for performing necropsies for preclinical safety and pharmacology studies in different strains, activities include collection of blood, bone marrow smear preparation, organ collection, weighing and preservation as per the study protocol requirement. Responsible for bone marrow smear preparation at the time of necropsy. Responsible for tissue QC and tissue preservation. Preparation of Histopathology slides for the microscopic evaluation includes some of the techniques like, fixation, trimming of fixed tissues, processing of tissues and staining and labelling of the slides before submitting for HP evaluation. Responsible for preparation of all the reagents and buffer: Buffers like NBF, MDF, DF, Decalcifying fluid, etc. Performing special stains like PAS. Responsible for stock stain preparation: Hematoxylin, Eosin, May-Grunewald, Giemsa stain, Schiff reagent and periodic acid. Quality check of stained slides. Prepare, peer review and revision of SOPs pertaining to department. Archiving of study samples (tissue blocks and tissue slides). Understanding of systems and process pertaining to safety, health, and environment. Operation and usage of relevant equipment used in non-clinical safety studies like biological centrifuge, laminar air flow, anesthetic machine, weighing balances, refrigerator, deep freezers, tissue Stainer, tissue processor, microtome, tissue floatation bath, tissue embedding station, etc. Preparation and review of SOPs. Archival of the study samples (tissues, embedded paraffin blocks, and slides).
