327 Lcms Jobs

Job Position: Study Director Location: Pragnapur, Hyderabad Company: Vivo Bio Tech Ltd Job Role: The Bioanalytical Associate role focuses on supporting in-vitro ADME studies and plasma sample analysis in preclinical drug development. The successful candidate will be integral in analyzing and interpreting bioanalytical data to support early-stage drug discovery efforts. Responsibilities Conduct routine ADME assays, such as protein binding and metabolic stability, to generate key data supporting drug development decisions. Prepare and analyze plasma samples for pharmacokinetic studies, including the measurement of drug concentration, metabolite profiling, and related biomarkers. Analyze data sets, provide scientific interpretation, and communicate results to cross-functional teams in a clear and concise manner. Maintain concise and accurate records of all study activities in accordance with industry guidelines and company policies. Troubleshoot assay issues, propose corrective actions, and implement process improvements to enhance the efficiency and reliability of bioanalytical data. Assist in the coordination of outsourced research studies or other tasks assigned by management. Requirements Bachelors degree in Analytical Chemistry, Biochemistry, or a related field. 5+ years of hands-on lab experience in bioanalysis, with a focus on ADME/PK studies and plasma sample analysis. Hands-on lab experience with ADME screening assays, such as protein binding and microsomal stability. Experience with plasma sample bioanalysis in support of non-clinical pharmacokinetic studies. Experience with LC-MS/MS, HPLC, UPLC, and related analytical techniques for the quantification and characterization of drug candidates in biological samples. Strong analytical and troubleshooting skills with the ability to interpret complex datasets. Nice-to-haves Familiarity with drug discovery and development, especially within preclinical research. Experience with quantitative LC-MS/MS bioanalytical techniques and ABSciex mass spectrometers. Knowledge of relevant bioanalytical software (e.g., Analyst, Prism). Thanks & Regards G NagaSravani|HRD nagasravani.g@virinchi.com

Responsibilities: (1) To conduct analysis such as GC, HPLC, Wet Chemistry, GC-MS, LC-MS, FTIR, UV-Vis, DSC, Particle Size Analyzer, Viscosity, Density etc.(2) To maintain Analytical Lab note books, procedures, documents and records(3) To maintain laboratory and work place as per norms(4) To maintain ISO 17025 and ISO 9001 management systems(5) To work safely and maintain housekeeping of the lab(6) To work in shifts as per requirement of the job(7) Implement SOP for the storage of analytical standards and reference samples at Thane under required conditions and maintain a database

Monitor progress of the reactions by using standard methods & analytical techniques (TLC,GC,HPLC, LCMS etc).Plan, setup, monitor, and workup chemical reactions independently.Isolate product & Optimize.

Setting strategy for evaluating and implementing new technologies within the Analytical Development department, with a particular emphasis on state-of-the-art separation techniques (HPLC/UPLC/LCMS/GC) and familiar with XRD, DSC etc and automation

Preparing test solutions, compounds, and reagents for conducting tests and advising and coordinating test procedures(qualitative and quantitative chemical and collect/physical analysis of raw materials

1. Coordinate with Sales team and Plant from Order punching to despatch details 2. Regular Follow up for the Payments from clients 3. Support sales team for Quotes, Ledgers, PI, Debtor reports, monthly and weekly sales reports

Planned purchase to maintain stock. Having knowledge in IT Hardware & Software Procurement. Creating PO & Buying Activities. Having a good Knowledge in material Follow-up with Vendor & Supplier.

Key Responsibilities: Strategic Actively imbibing the values and philosophy of PI Industries. Efficient contribution to the overall success of product innovation (PRI) through scientific contribution to objectives and targets being set by the leadership team. Fullfilling requirements and achieveing goals set by the Team Leader and Group Leader Working as a team member, contributing to the team objective with special focus on achiving and exceeding the set target. Development of individual & team strengths by attending trainings based on the regular feedback as an individual and as a team Operational Monitoring reaction masses using LCMS/GCMS. Execution of purity assessment and assay determination of samples using GC/HPLC/UFLC. Able to carry method development for challenging compounds through GC/GCMS/HPLC/UFLC Developing methods on Prep HPLC for purification/isolation of impure compounds. Elucidating and confirming structures using NMR, FTIR and LCMS/MS Ensure the scheduled performance of calibrations, Preventive maintenance and troubleshooting of core analytical instrument. Following the set instrument maintenance practices like periodic solvent changes, system flushing, etc. Assist the other team members in day to day activities like sample preparation, method developments, report generation and data management. Following safety practices with out fail. Financial Planning the activities with existing resources and infra structure. Suggesting the cost-effective areas to the Team Leader / Group Leader Developing methods to improve the environment safety and to reduce the cost. People Collaborate with team members and cross functional teams to meet research objectives. Develop and foster positive relationships with other teams and support groups to maximize cooperation and consequent benefit to objective delivery Should be able to work in multitasking environment Ensure team harmony through collaboration and active participation in all team discussion Apart from the above responibilities, specific responsibilities of Research scientists Note : The Associate would in any of the areas listed below based on the requirement and should have sufficient knowledge and expertise in the area alloted as listed below 1. HPLC/UFLC Candidate should be well versed with normal and reverse phase chromatography techniques. Able to optimize chromatographic methods Keen knowledge on low level analyte-impurities quantification by HPLC. 2. LCMS SQD & TQD Well versed with operations of one or more makes of LCMS-SQD & TQD instruments. Aware of basic principles related to mass spectrometry, sources, analysers and detectors. Hands on experience in analysis of compounds using LCMS instrument and releasing the mass confirmation reports. Keen knowledge on ppb / ppm level quantification of analytes from AI, formulations, various matrices like microsomes, soil, plant extracts by LCMSMS. Perform possible structural elucidation/Identification of degradants/metabolites/impurities using LCMS/MS 3. NMR Perform suitable 1D/2D NMR experiments based on the requirement and confirm one among proposed structures or propose a new structure. Manage the NMR activities viz, perform routine NMR (1D&2D) analysis, QNMR, cryogen replenishing. Keen knowledge of NMR technology & instrument maintenance. 4. Physchem assays Have hands on knowledge of various in vitro ADME/ physchem assays like solubility, LogP, pKa and in vitro Metabolic stability assay. Able to develop methods, check method compatibility for accuracy, precision, matrix effect and apply it further for the quantification of formulations, plant extracts, various matrices like soil, microsomes etc. Perform the microsomal stability experiments to determine half-life and Clint. Awareness about Met ID using various scans, fragmentation tree & HRMS will be an added advantage. Knowledge about sample preparation and analysis of photo stability and hydrolytic stability. 5. Prep-HPLC Able to develop a robust chromatographic method both at analytical and preparative scale, by designing cost effective methods for chiral and achiral molecules. Knowledge of chiral chromatography and isolation of enantiomers using preparative HPLC. Please share updated resume on e-mail id Shubhi.chandnani@piind.com Mobile - 8875001305

Role Overview: As a QC Team Leader at our company located in Ambernath, Maharashtra, your primary responsibility will be to lead a team of 30+ members in the QC-AMV team, including LC-MS, Nasal, and FT-NIR teams, for regular testing and method validation activities. You will also provide backup support to the QC Head of Department (HOD) by managing daily updates, commercial output, monthly sample status, training, review meetings, and coordination with stakeholders to align work requirements. Your role will involve executing and approving various types of Quality Management System (QMS) processes, identifying scientific root causes, implementing corrective and preventive actions (CAPA), and ensuring laboratory compliance. Key Responsibilities: - Lead the QC-AMV team for regular testing and method validation activities with analytical knowledge and leadership qualities to achieve company goals. - Support the QC HOD with daily updates, commercial output, monthly sample status, training, review meetings, and stakeholder coordination. - Execute and approve different QMS processes, identify root causes, implement CAPA, and maintain lab compliance. - Design and execute analysis planning, data interpretation, and presentation to the HOD. - Provide guidance to team members, monitor key performance indicators, and lead QC-AMV work in the absence of the QC HOD. - Collaborate with cross-functional teams, stay updated on industry trends, and ensure compliance with GLP and health, safety, environmental systems. - Manage work in all shifts and travel to other sites as per company policy. Qualifications Required: - Master's degree in Science or Bachelor's/Master's in Pharma. - Strong analytical knowledge and expertise in modern analytical instruments (HPLC, GC, LC-MS, NIR, Nasal performance testing). - Work experience in QC, AMV, and AD departments. - Leadership skills, problem-solving abilities, strategic mindset, organizational skills. - Knowledge of Chromeleon 7.2 and Sciex software is advantageous. - Experience in GMP, USFDA/EU audits. - Excellent communication skills. (Note: Additional details about the company were not included in the provided job description.),

About the Team At Nutanix Cloud Manager, we are trying to build the next generation platform to help enterprises model, develop and manage applications. We want to give them the ability to encapsulate not only infrastructure but even the application its architecture and deployment as code. You will be reporting to the Senior Manager Engineering, QA - NCM Team. Your Role As the gatekeeper of our product quality, you would be required to ensure that product releases adhere to the highest quality norms. You will design and develop a testing framework for our products and be part of a ruthless quality team. You will develop test tools, test cases, maintain test beds, and provide metrics and test/quality status. What You Will Bring: Be a self-starter who can flourish in a fast-paced technology company Be the owner of our automation and delivery systems Be actively participating in Coding & Code reviews Have expertise in languages like Python, JAVA Have expertise with automation and building tools such as Selenium, JMeter and Jenkins Strong systems background (Linux systems with exposure to Process, Memory and IO Management tools You will enable our engineers to generate known-quality releases with every commit, discover defects early and iterate fast. Thrive on working on open-source technologies. Excellent programming and scripting capabilities to develop code for automated tests. Should have an extremely good problem-solving approach with good hands-on knowledge of Algorithms & Data Structures.

Setting strategy for evaluating and implementing new technologies within the Analytical Development department, with a particular emphasis on state-of-the-art separation techniques (HPLC/UPLC/LCMS/GC) and familiar with XRD, DSC

Setting strategy for evaluating and implementing new technologies within the Analytical Development department, with a particular emphasis on state-of-the-art separation techniques (HPLC/UPLC/LCMS/GC) and familiar with XRD, DSC etc and automation

We are seeking a talented and motivated R&D Executive specializing in synthesis to join our Agrochemical research and development team. The ideal candidate will be responsible for developing, optimizing

We are seeking a talented and motivated R&D Executive specializing in synthesis to join our Agrochemical research and development team. The ideal candidate will be responsible for developing, optimizing,

1.Understand the project requirements & deliverables from supervisor/manager 2.Carry out literature search by using SciFinder, Reaxys and other search engines 3.Comprehend and discuss the MSDS with supervisor/ team members.

Preparing test solutions, compounds,and reagents for conducting tests and advising and coordinating test procedures(qualitative and quantitative chemical and collect/physical analysis of raw materials.

We are seeking a talented and motivated R&D Executive specializing in synthesis to join our Agrochemical research and development team. The ideal candidate will be responsible for developing, optimizing,

Conduct chemical synthesis of new and existing agrochemical compounds in the lab. Develop and optimize synthetic routes and reaction conditions to improve yield, purity, and cost-effectiveness.

Conduct chemical synthesis of new and existing agrochemical compounds in the lab. Develop and optimize synthetic routes and reaction conditions to improve yield, purity, and cost-effectiveness.

Understand the project requirements & deliverables from supervisor/manager.Carry out literature search by using SciFinder, Reaxys and other search engines.Comprehend and discuss the MSDS with supervisor/ team members

Analytical method development Analytical method validation Stability studies Extractable and leachable Standards generation Calibration of Instruments All related works as per USFDA and NABL norms

Setting strategy for evaluating and implementing new technologies within the Analytical Development department, with a particular emphasis on state-of-the-art separation techniques (HPLC/UPLC/LCMS/GC) and familiar with XRD, DSC etc and automation

Setting strategy for evaluating and implementing new technologies within the Analytical Development department, with a particular emphasis on state-of-the-art separation techniques (HPLC/UPLC/LCMS/GC) and familiar with XRD, DSC etc and automation.

Setting strategy for evaluating and implementing new technologies within the Analytical Development department, with a particular emphasis on state-of-the-art separation techniques (HPLC/UPLC/LCMS/GC) and familiar with XRD, DSC etc and automation.

Provide Platform Security Strategy for the organization. Security Advisory role in design of platform tools. Assist in Selection, design, implementation and maintaining secure cryptographic solutions using Thales, Fortanix HSM technology. Security Advisory role in formulating hardening guidelines for above mentioned tools. Strategize and formulate high and low-level monitoring mechanism for platform security technology and best practices, manage the organization's platform security strategy & controls and keep abreast of new technologies and capabilities. Strategize and formulate high and low-level monitoring mechanism for security posture of platform technology deployments and advise measures to improve them. Possess and maintain in-depth technical and business knowledge of aspects of Special Security Technologies KMS, HSM. Possess and maintain broad technical and business knowledge of aspects of security technologies including Cryptographic technologies, basics of networking etc.