Invitro Bioanalytical Scientist

2 - 7 years

3 - 8 Lacs

Posted:1 day ago| Platform: Naukri logo

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Job Type

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Job Description

Job Title: Invitro Bioanalytical Scientist

Job Location: Bangalore/Hyderabad

About Syngene :

and manufacturing organization offering integrated scientific services from early discovery to commercial

supply.

At Syngene, safety is at the heart of everything we do personally and professionally. Syngene has

placed safety at par with business performance with shared responsibility and accountability,

including following safety guidelines, procedures and SOPs, in letter and spirit

Mandatory expectation for all roles as per Syngene safety guidelines

  • Overall adherence to safe practices and procedures of oneself and the teams aligned
  • Contributing to development of procedures, practices and systems that ensures safe operations and compliance to companys integrity & quality standards
  • Driving a corporate culture that promotes environment, health, and safety (EHS) mindset and operational discipline at the workplace at all times.
  • Ensuring safety of self, teams and lab/plant by adhering to safety protocols and following environment, health, and safety (EHS) requirements at all times in the workplace.
  • Ensure all assigned mandatory trainings related to data integrity, health, and safety measures are completed on time by all members of the team including self
  • Compliance to Syngene s quality standards at all times
  • Hold self and their teams accountable for the achievement of safety goals
  • Govern and Review safety metrics from time to time

Core Purpose of the Role :

  • To participate in sample processing for PK, ADME assays and handling of LCMS/MS. Ability to adapt to the dynamic team environment
  • Processing of different matrices samples of PK studies
  • Optimization of test compounds manually as well as automated on LCMS/MS
  • Develop methods with the team lead
  • Independently handling of HPLC for UV based samples analysis.
  • Documenting the lab note books online and compound management

Role Accountabilities

Leadership Capabilities

Syngene Values

All employees will consistently demonstrate alignment with our core values

Excellence

Integrity

Professionalism

Accountabilities as a Syngene Leader (only for Leadership Hires)

  • Champion effective Environment, Occupational Health, Safety and Sustainability (EHSS) practices for the company and oversee compliance with those practices within Biologics business. Play an active leadership role in monitoring and verifying safety performance through Gemba walks and other safety-led activities.
  • Foster a corporate culture that promotes an environment, occupational health, safety, and sustainability (EHSS) mindset as well as the highest standards of quality, integrity, and compliance.
  • Put people at the heart of our success by providing clear, active leadership defined by the Syngene leadership framework setting high standards of people management, career planning and talent retention as a priority.

Specific requirements for this role

1. Experience

2. Demonstrated Capability

3. Education

Experience

Minimum 3-5 years of experience in handling ADME assays and HPLC and LCMS/MS

Skills and Capabilities

  • Expertise in column selection, mobile phase selection, solvent preparations and sample processing techniques such as protein precipitation, liquid-liquid extraction and solid phase extraction is mandatory
  • Sample processing of New chemical entities from various in-vitro and in-vivo studies executed in Preclinical discovery by using appropriate extraction methods
  • Should be able to develop and validate LC-MS based qualitative/quantitative methods and apply them in routine analysis
  • Should be well versed with internet-based literature search and capable of implementing the Learnings as and when required
  • Candidate is expected to have basic understanding in interpretation of Mass/UV Spectra
  • Should ensure preventative maintenance and calibration schedules of HPLC & mass spec by coordinating with vendor and support staff
  • General understanding of Drug metabolism and Pharmacokinetics
  • Should be able to deliver scientific presentation in departmental journal club and write official Project reports

Education

M. Pharm in Pharmaceutical sciences, Pharmaceutical Analysis who has interest and passion for LC/MS related bioanalysis.

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