Project Title Studying Leishmania differentiation associated processes using multi-OMICS approach Project Overview About the Project Join an exciting research initiative focused on understanding the complex biological processes underlying Leishmania differentiation through cutting-edge multi-OMICS methodologies. This project represents a unique opportunity to contribute to groundbreaking research in parasitology and infectious disease biology using advanced genomics, transcriptomics, proteomics, and metabolomics approaches. Key Responsibilities Conduct multi-OMICS analyses specifically focused on Leishmania differentiation processes Maintain and culture Leishmania parasites under various differentiation conditions Perform laboratory experiments related to promastigote-to-amastigote differentiation studies Execute sample preparation protocols for genomics, transcriptomics, proteomics, and metabolomics analyses Analyze and interpret complex biological datasets using specialized bioinformatics tools Monitor parasite viability and differentiation markers throughout experimental procedures Maintain detailed research records and contribute to scientific publications Collaborate with interdisciplinary research teams on Leishmania biology projects Present research findings at team meetings and scientific conferences Support grant writing and project reporting activities Required Qualifications Master's degree in Life Sciences, Biotechnology, Microbiology, Parasitology, or related field Minimum 1-2 years of hands-on experience working with Leishmania parasites Demonstrated expertise in Leishmania cultivation, maintenance, and parasite handling protocols Strong background in molecular biology and parasitology techniques Experience with axenic culture methods and parasite viability assays Knowledge of OMICS technologies and data analysis pipelines Excellent written and verbal communication skills Ability to work independently and as part of a collaborative team Essential Experience Requirements Direct laboratory experience with Leishmania species (L. major, L. donovani, or L. infantum) Proficiency in promastigote and amastigote culture techniques Experience with Leishmania differentiation assays and stage-specific markers Knowledge of parasite infectivity studies and host-parasite interactions Familiarity with biosafety protocols for working with infectious agents Preferred Qualifications Experience with multiple Leishmania species and strains Hands-on experience with next-generation sequencing technologies applied to parasites Familiarity with proteomics and metabolomics workflows for parasitic organisms Experience with data visualization and scientific writing in parasitology Knowledge of pathway analysis and systems biology approaches in parasite research Previous work on parasite differentiation or development studies Experience with macrophage infection models What We Offer Competitive monthly salary of ₹31,000 plus House Rent Allowance Opportunity to work on cutting-edge Leishmania research with international recognition Access to state-of-the-art parasitology laboratory facilities and BSL-2 containment Professional development and specialized training in advanced OMICS technologies Collaborative research environment with leading parasitologists and systems biologists Potential for co-authorship in high-impact parasitology and infectious disease journals Career advancement opportunities within established parasitology research programs Application Requirements Interested candidates should submit: Detailed curriculum vitae highlighting specific Leishmania research experience Cover letter describing previous work with Leishmania parasites and relevant techniques Academic transcripts Contact information for two professional references familiar with your parasitology work Any relevant publications or research portfolio demonstrating Leishmania expertise Application Deadline Applications will be reviewed on a rolling basis until the position is filled. Candidates without demonstrated Leishmania experience will not be considered. Job Type: Full-time Pay: ₹31,000.00 per month Schedule: Day shift Ability to commute/relocate: Whitefield, Bengaluru, Karnataka: Reliably commute or planning to relocate before starting work (Required) Education: Master's (Required) Experience: Research: 1 year (Required) Language: English (Required) Location: Whitefield, Bengaluru, Karnataka (Required) Work Location: In person
As a Junior Research Fellow (JRF) at the Institute of Bioinformatics (IOB), you will be working on the CSIR-funded project "Multi-Omics Approach to Study Ion Channels Altered Pathways in Esophageal Squamous Cell Carcinoma". Your responsibilities will include: - Conducting research using multi-omics approaches to study ion channels altered pathways in esophageal squamous cell carcinoma - Collaborating with a team of interdisciplinary scientists to analyze and interpret data - Presenting research findings at conferences and writing scientific papers for publication To be eligible for this position, you must hold an M.Sc./M.Tech in Bioinformatics/Computer Science. Preference will be given to candidates with experience in programming languages such as Python, Perl, or R. It is preferable, but not mandatory, to have cleared a national-level examination and obtained a research fellowship (e.g. GATE/CSIR/UGC-NET, JRF exams conducted by DBT/ICMR). The selected candidate will be enrolled in a Ph.D. program at Manipal Academy of Higher Education (MAHE), Manipal. The project duration is two years, and you will be paid until the completion of your Ph.D. The upper age limit for the JRF position is 28, with a relaxation of up to five years for candidates from reserved categories. To apply, please send your curriculum vitae along with the names and contact information of three references to careers@ibioinformatics.org. The deadline for submitting applications is March 27, 2025 (Thursday). Institute of Bioinformatics (IOB) is an internationally renowned interdisciplinary research institution that has made significant contributions in the fields of bioinformatics, multi-omics, and systems biology. Founded in 2002 by Akhilesh Pandey, M.D. Ph.D., IOB is a recognized research center of Manipal Academy of Higher Education (MAHE) with grants from key funding bodies including DBT/Wellcome Trust India Alliance, DBT, DST, and ICMR. With a strong track record in training scientists through its Ph.D. program, IOB offers a vibrant and collaborative research environment for aspiring researchers.,