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6.0 - 10.0 years

0 Lacs

karnataka

On-site

As an In vitro ADME Scientist at Syngene, your primary responsibility will be to support the ADME team by planning and conducting metabolic stability, Single point inhibition, reversible CYPIC50 inhibition, and TDI-IC50 shift assays using Human liver microsomes with the highest quality. Your role will require excellent time management and multitasking skills to meet the demands of high-volume ADME assays and complete multiple projects within specified timelines. This predominantly laboratory-based position necessitates contemporaneous recording of lab activities, adherence to safety rules, and maintenance of a safe workplace environment. Key responsibilities of the role include extensive experience in planning metabolic stability and CYP inhibition assays, designing and executing in-vitro Single point inhibition, reversible CYPIC50 inhibition, and TDI-IC50 shift assays with human liver microsomes. You will be expected to coordinate seamlessly with the BA-DMPK group, prepare SOPs and EOPs, report executed studies without any noncompliance, and present study results clearly in cross-functional scientific meetings. It is imperative to follow environment, health, and safety (EHS) requirements at all times in the workplace to ensure individual and lab/plant safety. The position requires candidates to hold an M Pharm. in any pharmaceutical science or M Sc. in biological science. Additionally, a comprehensive understanding of in vitro ADME assays, technical expertise in troubleshooting the assays, and a good knowledge of software tools such as Microsoft Excel and GraphPad Prism are essential. Demonstrated cross-functional leadership capabilities, experience with automation, and a minimum of six years of industrial experience in DMPK/ADME research are preferred qualifications. Behavioral skills expected from the candidate include the ability to be a team player, commitment to delivering study reports within agreed timelines, adaptability to changes in a dynamic lab environment, and effective communication with colleagues and collaborators during meetings and presentations. Syngene is an Equal Opportunity Employer, fostering a corporate culture that values diversity and inclusivity.,

Posted 3 days ago

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