33 Dmpk Jobs - Page 2

Eurofins Advinus is a premier preclinical and early development CRO offering drug discovery, preclinical and development stage contract research services in the areas of discovery services, regulatory Toxicology (Safety Assessment), DMPK, Analytical R&D Services and API CDMO. Eurofins Advinus manufactures drug substances to support Toxicology and early clinical studies. Job description: Planning/performing and reporting of acute toxicology studies Assist in preparation of SOP"™s, Protocols and Reports Participate in GLP / AAALAC related activities Literature search Maintenance of animal house and relevant documents as per GLP and AAALAC norms. To Assist and work along with SD and TC in Plann...

Preferred candidate profile M. Pharm (Pharmacology) / M.Sc. (Biochemistry / Pharmaceutical Chemistry) with 6-9 years or Ph.D. with 2-5 years' experience in PBPK & PK/PD modelling & Gastro plus; Simcyp software Role & responsibilities Experience in the development and application of pharmacometric models to support drug development and regulatory submissions Extensive experience with non-linear mixed effects modelling Proficient with software tools like PBPK models, Phoenix, R, PoPK, QSP modelling or similar platforms Strong background in pharmacokinetics/pharmacodynamics (PK/PD) modelling, First-in-human dose predictions. Collaborate with clinical pharmacology, biostatistics, and other inter...

Preferred candidate profile M. Pharm (Pharmacology / Pharmaceutical Analysis) / M.Sc. (Biochemistry / Pharmaceutical Chemistry / Analytical Chemistry) with 3 - 6 years experience in Bioanalytical DMPK & Invivo PK. Role & responsibilities Planning and execution of invivo preclinical pharmacokinetic studies, invivo tissue distribution & mass balance studies in rodents. Expert in method development of NCEs using LC-MS/MS system Well verse with extraction techniques of molecules from various matrices like plasma/urine/tissues Experienced in surgical skills for rodents PK, excretion studies Conduct Bioanalysis of samples from in-vivo pharmacokinetic, tissue distribution studies, PK-PD & TK studie...

Preferred Candidate Profile: M. Pharm (Pharmacology / Pharmaceutical Analysis) / M.Sc. (Biochemistry / Pharmaceutical Chemistry / Analytical Chemistry) with 5-8 years or Ph.D. with 2-5 years experience. Role & responsibilities Experience in designing, performing, and interpreting metabolite identification studies- Invitro and Invivo. Proficient in using LC-MS/MS, HRMS, and other analytical techniques for identification of metabolites and its soft spots. Ability to analyze complex data sets and structural interpretation for Phase-1, 2, and 3 metabolites. Strong understanding of drug metabolism principles and pathway. Experience with regulatory documentation and submissions Experience in DMPK ...

Role & responsibilities To perform in vitro ADME assays (solubility, metabolic and plasma stability, CYP inhibition, plasma protein binding studies etc.) Design, conduct and report data from in vitro metabolism studies using various cellular and subcellular systems, e.g., microsomes, hepatocytes, recombinant CYPs/UGTs and transfected cells. Perform assays using automated workstations. To design, program and implement study protocols in automated workstations. Ability to integrate metabolism and other supporting ADME data to predict druggability outcomes. To lead a group of 2-5 members and train juniors for the ongoing assays and technologies. Maintain labs & comply with SHE/regulatory guidel...

Hiring for Research Associate/ Sr. Research Associate for In- Vivo PK Studies -DMPK (Bangalore/Hyderabad Location) JOB DESCRIPTION Research Associate/ Senior Research Associate Department: Biology / DMPK Experience: 3-8 Years (In- Vivo PK studies) Key Responsibilities: Expert handling of laboratory animals like rat, mice, Guniea Pig and Rabbits. Dose administration to experimental animals by different routes like oral (p.o.), intravenous (i.v.), intraperitoneal (i.p.), subcutaneous (SC) etc. Cannulation of jugular vein, carotid artery, bile duct, portal vein and femoral vein in experimental rat model. Skilled in retro-orbital, Saphenous, Jugular bleeding, cardiac puncture, isolation of diffe...

Eurofins Advinus is a premier preclinical and early development CRO offering drug discovery, preclinical and development stage contract research services in the areas of discovery services, regulatory Toxicology (Safety Assessment), DMPK, Analytical R&D Services and API CDMO. Eurofins Advinus manufactures drug substances to support Toxicology and early clinical studies. With over 30 years of GLP compliance and certification, Eurofins Advinus serves diverse industries such as Biotech, Pharmaceutical, Biological, Agrochemical, Nutraceutical and Cosmetic. Eurofins Advinus is the only contract research organization (CRO) in India to have developed data in support of 90+ end-to-end IND enabling p...

Bioanalyst who will be responsible for high-quality discovery bioanalysis to support preclinical in vitro ADME and in vivo PK studies. LC-MS/MS based bioanalytical techniques to analyse biological samples in support of Drug Discovery projects. Required Candidate profile Around 5-8 years of experience in discovery bioanalysis to support in vitro ADME and pharmacokinetic studies.