3 Upstream Operations Jobs

Date: 12 Aug 2025 Location: Bangalore, KA, IN, 560099 Custom Field 1: Manufacturing Services Job Description Designation: Deputy Manager Level: 7 - II Job Location: Bangalore The Company Syngene International Ltd. (BSE: 539268, NSE: SYNGENE, ISIN: INE398R01022), is an integrated research, development, and manufacturing solutions company serving the global pharmaceutical, biotechnology, nutrition, animal health, consumer goods, and specialty chemical sectors. Syngenes 4500+ scientists offer both the skills and capacity to deliver great science, robust data management and IP security, and quality manufacturing at speed, to improve time-to-market and lower the cost of innovation. With a combination of 1.9 Mn sq ft of specialist discovery, development and manufacturing facilities, as well as dedicated research facilities for Amgen, Baxter, Bristol-Myers Squibb and Herbalife, Syngene works with biotech companies pursuing leading edge science as well as multinationals including GSK and Merck KGaA. Position Summary We are seeking a highly motivated and skilled Process Engineer with a strong background in biopharmaceutical manufacturing or process design , preferably with expertise in upstream operations . This role focuses on upstream unit operations including bioreactor design and operation , centrifugation with an added advantage for candidates who bring cross-functional exposure to downstream purification processes as well. Functional Responsibilities Lead or support process design, continuous improvement, and optimization of upstream unit operations (e.g., seed train, production bioreactors, harvest systems) Develop, review, and approve process documentation including P&IDs, process descriptions, interface to Automation Work collaboratively with cross-functional teams in MSAT, Quality, Engineering and Operations to ensure seamless tech transfer and process implementation Troubleshoot process-related issues during manufacturing campaigns and provide real-time support Participate in capital projects involving design or retrofit of biopharmaceutical facilities, including equipment selection, specification, and commissioning/qualification Evaluate and implement process improvements for robustness, yield, and productivity enhancements Maintain awareness of new technologies and trends in upstream and downstream processing Primary Responsibilities Project Ownership: Accountable for the successful execution of projects from initiation through completion, ensuring all deliverables meet client expectations and regulatory standards. Quality Assurance: Responsible for ensuring that all processes comply with cGMP and other regulatory requirements, thereby safeguarding product quality and patient safety. Client Satisfaction: Ensure high levels of client satisfaction through effective communication, timely updates, and proactive problem-solving. Compliance and Risk Management: Identify and mitigate risks associated with technology transfer, ensuring that all operations are compliant with internal and external guidelines. Develop and validate process maps and models in collaboration with cross-functional teams. Adapt to additional tasks and responsibilities as assigned, demonstrating flexibility and a proactive approach. Education Bachelors, Masters in Biotechnology, Chemical Engineering, Mechanical Engineering, Industrial Process Engineering, or a related discipline 58 years of relevant experience in biopharmaceutical manufacturing or engineering-equipment design, preferably in a GMP-compliant environment In-depth knowledge of upstream operations such as bioreactor operation (mammalian, microbial) and centrifugation from instrumentation and P&ID to DCS level Exposure to solution preparation, downstream processing (chromatography, UF/DF, nanofiltration) is a plus Familiarity with process control systems (DeltaV, PLC/SCADA) and PAT tools is advantageous Familiarity to ASPEN, Auto CAD, 3D design along with CMMS tools for asset management Strong understanding of ASME BPE, cGMP, ICH, and regulatory expectations for biopharma manufacturing Excellent analytical, problem-solving, and communication skills Preferred Attributes Experience with single-use technologies (SUT) and Stainless-Steel technologies in bioprocessing Prior involvement in facility design or greenfield/brownfield projects Hands-on experience in process modelling or simulation tools (e.g., Aspen Plus, SuperPro, schedule pro Designer or similar) Lean Six Sigma or similar process improvement methodology certification is a plus but not a must Equal Opportunity Employer It is the policy of Syngene to provide equal employment opportunity (EEO) to all persons regardless of age, color, national origin, citizenship status, physical or mental disability, race, religion, creed, gender, sex, sexual orientation, gender identity and/or expression, genetic information, marital status, status with regard to public assistance, veteran status, or any other characteristic protected by applicable legislation or local law. In addition, Syngene will provide reasonable accommodations for qualified individuals with disabilities. Pls visit us at https://syngeneintl.com/ to know more about us and what we do. Show more Show less

Date: 12 Aug 2025 Location: Bangalore, KA, IN, 560099 Custom Field 1: Manufacturing Services Job Description Designation: Deputy Manager Level: 7 - II Job Location: Bangalore The Company Syngene International Ltd. (BSE: 539268, NSE: SYNGENE, ISIN: INE398R01022), is an integrated research, development, and manufacturing solutions company serving the global pharmaceutical, biotechnology, nutrition, animal health, consumer goods, and specialty chemical sectors. Syngenes 4500+ scientists offer both the skills and capacity to deliver great science, robust data management and IP security, and quality manufacturing at speed, to improve time-to-market and lower the cost of innovation. With a combination of 1.9 Mn sq ft of specialist discovery, development and manufacturing facilities, as well as dedicated research facilities for Amgen, Baxter, Bristol-Myers Squibb and Herbalife, Syngene works with biotech companies pursuing leading edge science as well as multinationals including GSK and Merck KGaA. Position Summary We are seeking a highly skilled and motivated Process Automation Engineer with a strong background in biopharmaceutical process design and/or manufacturing . The ideal candidate will bring hands-on expertise in automation systems , particularly within Upstream operations and add on experience in Downstream operations (chromatography, ultrafiltration/diafiltration, nanofiltration). This role offers the opportunity to work on cutting-edge projects in process automation, recipe management, and control system design using advanced platforms and will extend to digital transformation Functional Responsibilities Design, develop, and implement automation solutions for Upstream and downstream operations Develop process control strategies in compliance with ISA S88 standards for batch process automation Create, configure, and validate recipe management systems for complex biopharma operations Design and implement PLC-based control systems using platforms such as Siemens WinCC, PCS7, or similar Configure and maintain DCS platforms, including Siemens PCS7 and/or DeltaV from Emerson Collaborate with cross-functional teams including process engineering, validation, manufacturing, and quality Troubleshoot and resolve automation-related issues during project execution or manufacturing daily operations Author and review automation documentation including design specifications, FRS,SDS, HDS, URS, FAT, SAT, and validation protocols Implementing minor and major expansion projects on site and changes targeting optimisation as part of the operational support Primary Responsibilities Project Ownership: Accountable for the successful execution of projects from initiation through completion, ensuring all deliverables meet client expectations and regulatory standards. Quality Assurance: Responsible for ensuring that all processes comply with cGMP and other regulatory requirements, thereby safeguarding product quality and patient safety. Client Satisfaction: Ensure high levels of client satisfaction through effective communication, timely updates, and proactive problem-solving. Compliance and Risk Management: Identify and mitigate risks associated with technology transfer, ensuring that all operations are compliant with internal and external guidelines. Develop and validate process maps and models in collaboration with cross-functional teams. Adapt to additional tasks and responsibilities as assigned, demonstrating flexibility and a proactive approach. Education B.Tech/M.Tech in Industrial Process Engineering, Automation Engineering, Instrumentation & Electrical Engineering, Chemical Engineering or related fields. 7-10 years of relevant industry experience in biopharmaceutical automation (process design, commissioning, or manufacturing support) In-depth knowledge of biotech manufacturing processes, with specialization in Upstream automation, not limited to process including software writing and IT & infrastructure Experience with PLC and SCADA/DCS platforms: Siemens WinCC, PCS7, DeltaV, or comparable systems Proficient in batch process control, recipe creation as per ISA/S88 is a must Strong understanding of instrumentation, P&IDs, control strategies, and process control hardware/software integration Knowledge of GAMP5, 21 CFR Part 11 compliance, and other regulatory guidelines Hands-on experience in project executions including qualification phase (IQ/OQ/PQ) and on-floor operations Excellent communication and documentation skills Preferred Attributes Experience with single-use technologies (SUT) and Stainless-Steel technologies in bioprocessing Prior involvement in facility design or greenfield/brownfield projects Experience working with digital plant systems or in digital transformation initiatives in biopharma Exposure to data historians, automation analytics, and real-time monitoring systems Equal Opportunity Employer It is the policy of Syngene to provide equal employment opportunity (EEO) to all persons regardless of age, color, national origin, citizenship status, physical or mental disability, race, religion, creed, gender, sex, sexual orientation, gender identity and/or expression, genetic information, marital status, status with regard to public assistance, veteran status, or any other characteristic protected by applicable legislation or local law. In addition, Syngene will provide reasonable accommodations for qualified individuals with disabilities. Pls visit us at https://syngeneintl.com/ to know more about us and what we do. Show more Show less

As an organization at the forefront of innovation and one of the world's fastest-growing engineering services firms, we at Quest Global are seeking individuals with a wealth of experience and a deep passion for engineering. With a history spanning twenty-five years and a vision to become a centenary company, we are driven by aspiration, hunger, and humility. We are in search of humble geniuses who believe in the transformative power of engineering, individuals who see the impossible as an opportunity to innovate. Our ideal candidates are inspired by technology and perpetually motivated to design, develop, and test with the aim of being trusted partners for Fortune 500 customers. At Quest Global, we are a team of diverse engineers committed to engineering a brighter future for all. If you are eager to contribute to meaningful work and join an organization that values mutual success and learning from failures, we would love to hear from you. The individuals we are looking for are achievers and courageous challenge-crushers who possess the following characteristics and skills: Roles & Responsibilities: - Managing a team of highly energetic young engineers in terms of Quality, Delivery, and Performance Management - Demonstrating effective people management skills from Hiring to Performance, Competency, and retention - Taking responsibility for managing projects effectively, including Productivity and Continuous Improvement initiatives - Collaborating closely with Subject Matter Experts (SMEs) and Technical Managers to deliver value to customers - Overseeing customer engagement, meeting rhythms, and relationship management - Ensuring compliance with Company policies and setting a positive example for the rest of the team Required Skills (Technical Competency): - Master's or Bachelor's Degree in Mechanical Engineering or a related field, such as the Oil & Gas Industry, with 10 to 12 years of working experience - Excellent domain knowledge in Upstream operations (Reservoir Engineering, Wells, Geoscience, etc.) - Ability to coordinate schedules and project details with all involved stakeholders - Strong leadership and people management skills - Excellent communication skills Desired Skills: - Experience in the Oil & Gas industry - Excellent communication and presentation skills, with a strong capability in facilitating discussions and resolving conflicts - Experience working with internal and external stakeholders across different teams, cultures, and geographies If you are ready to be a part of a dynamic team that believes in collective success and continuous learning, we encourage you to apply for this exciting opportunity at Quest Global.,