Job
Description
You are a passionate and accomplished scientist looking to lead early discovery programs focused on phage and yeast display platforms at Enzene Biosciences Ltd. As a Senior Manager / Associate General Manager in the Discovery Services department, your role involves utilizing deep technical knowledge, program leadership, and strategic collaboration to translate display-generated leads into viable therapeutic candidates. In this role, you will lead and execute phage and yeast display discovery programs for antibody and peptide therapeutics. You will design high-throughput screening strategies, selection protocols, and affinity maturation campaigns, while overseeing library construction and validation with appropriate QC measures. Additionally, you will drive the characterization and ranking of hits using biophysical and biochemical techniques and collaborate closely with internal teams including Protein Sciences, Bioinformatics, Preclinical, and Regulatory. As a leader in this role, you will ensure project delivery against timelines, scientific objectives, and regulatory quality expectations. You will be responsible for supervising and mentoring a team of scientists and research associates, fostering their scientific growth. Supporting the generation of technical documentation, presentations, IP filings, and regulatory dossiers will also be part of your responsibilities. It is essential to stay updated on emerging display technologies, industry trends, and peer-reviewed advancements. The ideal candidate should possess a PhD in Biotechnology, Immunology, Protein Engineering, Molecular Biology, or a related field, along with 8-12 years of experience in the biotech/pharma industry or academia. Proven expertise in phage and/or yeast display, antibody structure-function, epitope mapping, and affinity maturation principles is required. Proficiency in molecular biology, protein purification, ELISA/SPR/BLI, and FACS is essential, as well as experience leading research programs and cross-functional teams. Exposure to next-generation sequencing (NGS) for library diversity analysis, computational antibody design, structural modeling tools, and alternative display systems is preferred. A track record of scientific publications, patents, or conference presentations in relevant fields is a plus. Joining Enzene Biosciences offers you the opportunity to lead innovative discovery programs in a global-scale biologics environment, work with cutting-edge platform technologies in antibody engineering and screening, and collaborate with world-class scientific and operational teams in a rapidly growing biotech company. Competitive compensation, a supportive culture, and strong scientific leadership are additional benefits of being a part of the Enzene team.,