Research Scientist 1 - DMPK & Bioanalytical Foundation for Neglected Disease Research

2.0 - 6.0 years

0 Lacs

karnataka

On-site

The key responsibility of the candidate will be to perform and analyze in vitro and in vivo DMPK studies to support drug discovery and development projects. You will be involved in planning, designing, and setting up DMPK experiments, handling instruments, maintaining the laboratory, and preparing and reviewing protocols. Furthermore, you will be responsible for writing reports, communicating with the project team, and presenting DMPK data in project meetings. Required technical skills include the ability to set up and perform physiochemical assays such as solubility and logP, experience in conducting in vitro DMPK assays (microsomal and hepatocyte stability, plasma stability, CYP inhibition, blood/plasma ratio), development and validation of bioanalytical methods across various biological matrices, analysis of in-vivo pharmacokinetic samples, knowledge of sample processing techniques (protein precipitation, liquid-liquid extraction, solid-phase extraction), proficiency in handling LC-MS/MS for quantitative analysis, protocol preparation, report writing, and presentation of DMPK data in scientific team meetings. Additional skills that would be beneficial for this role include experience in animal handling, conducting pharmacokinetic (PK) studies, working with cell lines such as Caco-2, ability to interpret pharmacokinetic data using Phoenix WinNonlin, experience in a GLP or GLP-like environment. Basic skills required for this position include the ability to work independently with enthusiasm and self-motivation, strong decision-making and problem-solving skills, effective collaboration and teamwork across multidisciplinary functions, knowledge of drug discovery and development processes, excellent oral, written, and interpersonal communication skills with proficiency in English, and proficiency in computer applications including word processing, spreadsheets, and presentation tools. Qualifications for this role include an M.Pharm or MS (Pharm) or PhD degree, industry experience of 2 to 5 years, and the candidate must be an Indian citizen. Salary will be commensurate with experience.,

Posted 1 week ago

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