121 Organic Synthesis Jobs - Page 3

Setting strategy for evaluating and implementing new technologies within the Analytical Development department, with a particular emphasis on state-of-the-art separation techniques (HPLC/UPLC/LCMS/GC) and familiar with XRD, DSC etc and automation Preparation and review of Specifications, Method of analysis procedures and Analytical development reports Experience in making lab SOPs & study report Experience 8 - 14 Years Industry Engineering Engineering Design R&D Quality Qualification Other Bachelor Degree Key Skills Research & Development Research & Development Executive Research & Development Manager R&D Chemist R&D Manager Agrochemical Chemical UPLC HPLC GC Chemical Research

Setting strategy for evaluating and implementing new technologies within the Analytical Development department, with a particular emphasis on state-of-the-art separation techniques (HPLC/UPLC/LCMS/GC) and familiar with XRD, DSC etc and automation Preparation and review of Specifications, Method of analysis procedures and Analytical development reports Experience in making lab SOPs & study reports Experience 9 - 15 Years Industry Pharma R&D Biotech Qualification Ph.D/Doctorate Key Skills Analytical Development R&D Manger AM R&D R&D Method Feasibility Green Field Projects Research and Development UPLC HPLC GC Chemical Research

R & D Executive For Agrochemical Industry in Saykha, Bharuch, Gujarat. Plan, setup, monitor, &workup chemical reactions independently. Monitor progress of the reactions by using standard methods & analytical techniques (TLC, GC, HPLC, LCMS etc)Isolate product & Optimize reaction conditions for improved yields & output. Industry- Leading pharma, CRO (Contract research Organization), Agrochemicals Pls mention this Visit our website for more details: Follow Linkdein Profile for more updates : Experience 4 - 10 Years Industry Engineering Engineering Design R&D Quality Qualification M.Sc Key Skills Chemical Research UPLC HPLC R&D R&D Chemist R & D Executive Research and Development Agro Chemical

Job Description Understand the project requirements & deliverables from supervisor/managerCarry out literature search by using SciFinder, Reaxys and other search engines.Comprehend and discuss the MSDS with supervisor/ team members.Identify and mitigate any potential safety risk with the help of Manager Plan, setup, monitor, and workup chemical reactions independently Monitor progress of the reactions by using standard methods and analytical techniques (TLC, GC, HPLC, LCMS etc).Isolate product and Optimize reaction conditions for improved yields and output Purify compounds by different methods using chromatography, distillation and crystallization etc.Characterization and identification of compounds using UV, IR, NMR, LCMS and GCMS etc Ensure parallel execution of multiple reactions conducted both by self and the team cale up of R&D developed products to kg scale and then technology transfer to pilot plant Troubleshoot as appropriate for successful execution with intimation to supervisor Discuss research findings and work plan on daily basis with supervisor/ manager and Mentor junior lab personnel.Document reactions, research findings/ observations accurately in lab note books to ensure data integrity.Participate in project meetings and prepare daily, weekly and monthly reports and submit to ManagerWriting regular updates, final reports, PDR preparations and inter departmental communications

Job description we are looking for PDL-synthesis candidate for a leading pharmaceutical API company at vizag location. Interested candidate should have experience in Involved in the multi step synthesis, handling reactions from mg scale to multi gram scale. Scale up from lab level to Kilo Lab Edu-Msc,chemistry, Organic chemistry,Analytical chemistry with 60% Exp-minimum 2yrs

Location - Bharuch, Ahmedabad, Vadodara Job description Plan, setup, monitor, &workup chemical reactions independently. Monitor progress of the reactions by using standard methods & analytical techniques (TLC, GC, HPLC, LCMS etc) Isolate product & Optimize reaction conditions for improved yields & output.

aganitha cognitive solutions is looking for Scientist (Computational Chemistry / Materials & Molecular Modeling) to join our dynamic team and embark on a rewarding career journey Conduct innovative research and experiments to develop new knowledge, products, or technologies within a specialized scientific field Design, plan, and execute scientific studies while ensuring compliance with safety and ethical standards Collect, analyze, and interpret data using advanced tools and methodologies to draw valid conclusions Prepare detailed technical reports, research papers, and documentation for internal use and external publication Collaborate with cross-functional teams, including engineers, analysts, and other scientists, to achieve project goals

Monitor progress of the reactions by using standard methods & analytical techniques (TLC,GC,HPLC, LCMS etc).Plan, setup, monitor, and workup chemical reactions independently.Isolate product & Optimize reaction conditions for improved yields & output Required Candidate profile Scale up of R&D developed products to kg scale and then technology transfer to pilot plant Sheetal Tanwar

Role & responsibilities : Project execution: Performance of the corresponding expected synthetic work to successfully achieve the required goals: Reaction setting Work-up Analyses measure and interpretation (expected) Compilation of all the required information in accordance to companys SOP Information to the project leader about potential/current problems during project development Taking additional responsibilities like maintenance of lab equipment's Handling projects with minimum guidance Trouble shooting skills in the synthesis Training and guiding juniors Preferred candidate profile MSc (Organic Chemistry). 0-3 years industrial experience with Process organic chemistry background Experience in multi-step organic synthesis. state-of-the-art scientific knowledge in technical background for synthesis and purification methods Good in English written and spoken recommendable Having enthusiasm to work in international environment and if required flexible to move abroad for short or long-time work. Willingness to learn HPLC, LCMS and NMR data recording Perks and benefits

Job Title: Research Associate API R&D Experience: 2-3 Years Qualification: MSc in Organic Chemistry Job Location: R & D, Mahape, Navi-Mumbai . Job Description: We are seeking a motivated and skilled Research Associate to join our API R&D team . The ideal candidate will have 2-3 years of experience in Active Pharmaceutical Ingredient (API) research and development, with a strong educational background in chemistry. Key Responsibilities: Conduct experiments for the development of APIs , including synthesis , optimization, and process development. Perform literature searches and study patents to design and develop cost-effective, scalable, and efficient synthetic routes. Optimize reaction parameters such as yield, purity, and productivity while adhering to project timelines. Work on process validation and transfer from the laboratory to pilot and production scale. Prepare and maintain accurate documentation, including laboratory notebooks, development reports, and other required records. Collaborate with cross-functional teams, including Analytical, Quality, and Regulatory departments, to ensure project alignment. Ensure compliance with GMP and safety protocols in all laboratory activities. Stay updated on advancements in API R&D and integrate innovative techniques into projects. Key Skills and Competencies: Strong knowledge of organic synthesis and process development. Experience with API manufacturing processes and regulatory requirements . Proficiency in analytical techniques such as HPLC, GC, and spectroscopy (NMR, IR, MS). Good problem-solving skills and attention to detail. Strong documentation and reporting skills. Ability to work independently and in a team environment. Preferred Skills: Experience in handling scale-up operations and technology transfer. Familiarity with regulatory guidelines such as ICH, FDA and EMEA.

Understand the project requirements & deliverables from supervisor/manager Carry out literature search by using SciFinder, Reaxys and other search engines Comprehend and discuss the MSDS with supervisor/ team members Plan, setup, monitor, and workup chemical reactions independently Monitor progress of the reactions by using standard methods and analytical techniques (TLC, GC, HPLC, LCMS etc.) Isolate product and Optimize reaction conditions for improved yields and output Purify compounds by different methods using chromatography, distillation and crystallization etc. Characterization and identification of compounds using UV, IR, NMR, LCMS and GCMS etc Scale up of R&D developed compounds to kg scale and technology transfer to pilot plant Discuss research findings and work plan on daily basis with supervisor/ manager Prepare daily, weekly and monthly R&D work reports and submit to Manager Regular lab duties including equipment maintenance, chemical inventory and lab clean-up Follow health and safety guidelines and safe working practices Maintain strict IP Confidentiality and adhere to all related data privacy policies.

Job Title - R&D Chemist Experience: 4+ years in R&D Industry- Leading pharma, CRO (Contract research Organization), Agrochemicals JOB DUTIES AND RESPONSIBILITIES (Please mention in below table) Plan, setup, monitor, and workup chemical reactions independently Monitor progress of the reactions by using standard methods and analytical techniques (TLC, GC, HPLC, LCMS etc) Isolate product and Optimize reaction conditions for improved yields and output Purify compounds by different methods using chromatography, distillation and crystallization etc. Characterization and identification of compounds using UV, IR, NMR, LCMS and GCMS etc Ensure parallel execution of multiple reactions conducted both by self and the team Scale up of R&D developed products to kg scale and then technology transfer to pilot plant Troubleshoot as appropriate for successful execution with intimation to supervisor Pls sent your resume mentioning the Below details Present CTC : Expected CTC: Company Name : Current Location: Notice Period: Native Place : If any candidates is suitable for this opening please sent me your updated profile on this mail id.

- Conducting primary research with selected industry and regulatory sources - Developing and analyzing data - Interpreting findings to derive business implications for the clients decision-making sent updated resume at

Job Overview The Senior Principal Scientist in Peptides Purification will lead, design, and execute advanced research projects focused on the purification of peptide molecules Key Stakeholders: Internal Operations, Marketing, Quality, Finance, Sr. leaders Key Stakeholders: External Vendors and Customers on need basis Reporting Structure Functional reporting to Associate Director R&D Experience Minimum 10+ years of hands-on experience in peptide purification Competencies Leadership skills Ability to connect the dots in various situations, seeing the risk and keep the mitigation plans. Clear communication. Analytical mindset. Quick and effective decision making. Stakeholder management Roles and Responsibilities: Lead and manage peptide R&D Purification projects from inception to completion, ensuring timelines, budgets, and quality standards are met. Design and implement advanced purification strategies for peptide molecules Develop and implement strategic plans for peptide research and development in alignment with organizational goals and objectives. Purification of Peptide impurities by using solution & solid phase technique. Create the Innovative Research and Development Environment Train and guide the research teams to improve on developing/ adopting new chemical technologies. Drive positive & major EHS Cultural transformation Initiatives Take ownership of solvent recovery and yields improvement. Mentor and manage a team of scientists and research associates working in peptide purification. Ensure compliance with regulatory guidelines and requirements governing peptide drug development and help the teams in successful regulatory inspection with no critical observations. Qualifications Ph.D. in Biochemistry, Organic Chemistry, Chemical Engineering, or related field with a focus on peptides.

Role & responsibilities Conduct synthesis and process development experiments under the guidance of R&D scientists. Prepare reagents, carry out reactions, and monitor processes using TLC, HPLC, GC, NMR, and other tools. Record experimental procedures and results meticulously in lab notebooks and data sheets. Support scale-up trials from gram to kilogram scale; assist in transferring processes to pilot/manufacturing. Work on a range of chemistries including esters, surfactants, polymer intermediates, and fi ne chemicals. Assist in analytical method development, sample submissions, and customer evaluations. Maintain lab hygiene, safety protocols, and raw material inventory. Preferred candidate profile B.Sc. / M.Sc. in Organic Chemistry, Applied Chemistry, or Chemical Sciences. 13 years of hands-on lab experience in a chemical or specialty chemical R&D setup. Exposure to synthesis, reaction monitoring, and basic analytical techniques. Basic understanding of scale-up challenges and process parameters. Good documentation, problem-solving, and communication skills.

Key Responsibilities Conduct synthesis and process development experiments under the guidance of R&D scientists. Health insurance Provident fund

Strategic Efficient contribution to the overall success of Product Innovation by driving innovation and team performance according to objectives and targets being set by HoF of Process Research. Fulfilling requirements as set by Group Leader and Team Leader within specific Research Projects Ensuring the security of intellectual property for Product Innovation (patent applications) Operational Keep self updated on new developments and techniques in synthetic chemistry and process research Continuous documentation and reporting of all research results obtained within the area of responsibility as defined in the SOP / guideline Carrying out experiments with knowledge of SDS of starting materials and reagents used. Seek functional support actively from Senior RS/Team Leader Carrying out literature search by use of available tools (Reaxys/SciFinder/Patents etc.) Carrying out synthetic experiments safely, efficiently, capturing all the experimental procedures and data Updating the GL/TL on the functional progress/issues of the project on a regular basis Constructive and active participation in all technical and functional meetings of the Team Responsible for individual safety and housekeeping of the lab People Actively imbibing the values and philosophy of PI Industries Support Team members by providing peer feedback Foster an environment of knowledge sharing within the Team Email ID - Deepanshu.bhatt1@piind.com Mobile- 8696900583

Candidate should be exeprinecd in process development in R&D in API synthesis Candidate with the exeprience of handelling Photo reactor will be prefered . Experience in Vitamin synthesis will be prefered

Role & responsibilities Perform lab experiments as per experiments planning in consultation with senior Write the lab note book properly at time of performing experiment Discuss the experiment observation with senior Wear proper PPE while handling chemicals and performing experiments Submit the sample to analytical as per experiment requirement and planning Collect the test report from analytical lab Maintain the project documents and file properly Maintain the lab chemicals as per hazards and compatibility data, study the MSDS sheet Maintain the raw materials, solvents stock and store it properly Maintain the lab glassware and stock Clean and maintain work place area

Job Responsibilities - Lead electronic laboratory notebook (ELN) software administration and management. Provide ELN trainings to new joiners. Connect with third party and internal stakeholders on regular basis for implementation and troubleshooting. - Literature survey as per order forms. - Supervision of experimental work in laboratory. - Ensure laboratory safety and compliances - Ensure availability of raw materials and equipment required for the execution of experimental planning - Understand the safety aspects of all reactions and chemicals to be used in laboratory - Play the role of ERT and shift incharge - Perform night duties as per site philosophy -To ensure 100% compliance on ERA and zero safety incidents in lab - Laboratory management: disposal of samples, disposal of chemical waste, chemical inventory - Equipment maintenance: ensure PM of allocated instruments and inventory of spares

Purpose Statement: Handle high pressure reactions at R&D lab operations, compile data and ensure adherence to safety and incorporate best laboratory housekeeping practices. - Responsible for the availability of raw materials, catalysts and instrument spares as per high pressure lab requirements. -To analyze quality results and discuss the experimentation plan and parameters with Research Incharge. - Understand the safety aspects of all reactions, chemicals and catalysts to be used in high pressure reactions. - Ensure the proper setup ( compatibility of autoclave, high pressure addition pumps, thermostats etc) as planned. - Carry out reaction process as per the provided plan, get the analysis done for raw materials, catalysts , in process reaction intermediates and product. - Record all observations and give suggestions for improvement. - Report any breakdown, abnormal functioning of instruments in high pressure lab. - Ensure proper housekeeping of the lab. - Maintain highest safety practices while working by using required PPEs (Personal protective equipment). - Maintain the log sheets of all the experiments regularly with critical observations and feed the data into Electronic Lab Notebook (ELN). - Ensure working in lab as per SOP's provided. - Maintain stock of all the chemicals, catalysts and instrument spares required as per 5'S' (sort, set-in-order, shine, standardize, sustain) - After reaction completion, decontaminate the autoclave/instruments properly. - To ensure proper and complete recovery/quenching of catalysts after reaction. - To ensure proper and safe storage of catalysts and maintain its record. - Segregate effluents as per the lab system. - To undergo trainings as per schedule. Experience 2-7 Years. Qualification M.Sc Organic Chemistry or equivalent. Certifications/Trainings Analytical & Waste Treatment, Process Safety training, Process Development training preferred

- Responsible for the availability of raw materials as per lab requirements -To analyse quality results and discuss the experimentation plan with Research Incharge. - Understand the safety aspects of all reactions and chemicals to be used - Ensure the setup ( reaction assembly, distillation, filtration, reaction work-up, crystallization) as planned - Carry out reaction process as per the provided plan, get the analysis done of raw material , in process reaction intermediate and product - Record all observations and give suggestions for improvement - Ensure proper housekeeping of the lab - Maintain highest safety practices while working by using required PPEs (Personal protective equipment) - Maintain the log sheets of all the experiments regularly with critical observations and feed the data into Electronic Lab Notebook (ELN) - Stack of all the chemicals & glassware as per 5S (sort, set-in-order, shine, standardize, sustain) - After reaction completion, decontaminate the glass apparatus

- Responsible for the availability of raw materials as per lab requirements -To analyse quality results and discuss the experimentation plan with Research Incharge. - Understand the safety aspects of all reactions and chemicals to be used - Ensure the setup ( reaction assembly, distillation, filtration, reaction work-up, crystallization) as planned - Carry out reaction process as per the provided plan, get the analysis done of raw material , in process reaction intermediate and product - Record all observations and give suggestions for improvement - Ensure proper housekeeping of the lab - Maintain highest safety practices while working by using required PPEs (Personal protective equipment) - Maintain the log sheets of all the experiments regularly with critical observations and feed the data into Electronic Lab Notebook (ELN) - Stack of all the chemicals & glassware as per 5S (sort, set-in-order, shine, standardize, sustain) - After reaction completion, decontaminate the glass apparatus and give for further cleaning. - Segregate effluents as per the lab system

Role & responsibilities 1. Good knowledge of synthetic organic chemistry. 2. Performing literature searches for the molecules that reaction is being carried out and understanding of the chemistries Strong skills in designing, optimizing, and scaling up synthetic chemical processes. 3. Plan and conduct experiments for chemical synthesis, ensuring the process can be reproduced and scaled up efficiently. 4. Design scalable synthetic processes that avoid patent infringement, especially for API (Active Pharmaceutical Ingredients) development. 5. Improve processes to make them industrially feasible, reduce costs, and enhance efficiency for existing products. 6. Validate synthetic processes at both laboratory and production plant scales. 7. Plant support for trial & validation batches. And troubleshooting of plant concerns. 8. Literature survey through various scientific databases. 9. Interpretation of NMR (Nuclear Magnetic Resonance), IR (Infrared Spectroscopy), MS (Mass Spectrometry), XRPD(X-Ray Powder Diffraction)and chromatography data 10. Knowledge of scale-up processes, and familiarity with Good Manufacturing Practices (GMP) and ICH-guideline. 11. Hands-on experience with bench-scale and pilot-scale synthesis is essential. Skilled in preparing detailed reports, presentations and technical documents like SOPs, process development reports, costing sheets, and technology transfer documents. Preferred candidate profile M.Sc/ M. Pharm/ Ph.D in Pharmacy Interested Candidates can share their resumes on shikha.mishra@walterbushnell.com

As a Process Technology Engineer / Chemist within Process Science & Technology you will play a crucial role in Corteva s success. As a regional subject matter expert in India, you will be managing the chemistry and manufacturing technology of one or several of our commercial active ingredients. With a wide spectrum of responsibilities, you serve as a link between Global R&D and other critical regional functions such as External manufacturing, Procurement, Analytical and collaborating with internal and external partners to ensure successful technology implementation. You will further be responsible for improving and innovating existing technologies as we'll as implementing novel technologies for new active ingredients to increase production yield, reduce manufacturing costs, and improve plant operability and reliability. Role Description In this role, Process Technology Chemist/Engineer utilizes chemistry knowledge, engineering skills, product development experience and advanced problem-solving techniques to improve the manufacturing process for existing molecules and intermediates, troubleshooting process issues and to transfer existing or new technologies to new manufacturing plants. This person is a subject matter expert (SME) in chemistry and process technology / engineering for a specific molecule or portfolio of molecules along with their key intermediates. This person is the primary link between Global R&D and a manufacturing plant for that molecule. Specific Accountabilities Technology Stewardship: Owner and subject-matter expert of the Technology Documentation for the molecule and its intermediates. Production Support: Lead, Manage and Support manufacturing technology of one or multiple Corteva commercial active ingredients and address production issues. Technology transfer and startup support: Reduce production startup risk through we'll-executed technology transfers (lab-to-plant or site-to-site) and process reviews (as applicable). Responsible for continuous and step-change improvement to improve technology to reduce the cost of manufacturing such as yield improvement, cycle time reduction, solvent recovery and recycling, qualification of low-cost raw materials etc Primary Responsibilities Technology Transfer & Launch Support: Early engagement with Process R&D to ensure development of scalable and manufacturing processes and participate in Process Peer Reviews Lead technology transfer to identified manufacture partners for successful implementation technology at pilot and commercial scale Review documents from manufacturing plants such as PFD, P&IDs, PHA, mass balances, etc to identify gaps for smooth technology transfer. Provide technology input into development of manufacturing supply strategy (site selections) Continuous Improvement / Optimization Proactively identify and deliver value creation and technology improvement opportunities (eg yield / capacity increase, cost /waste / cycle time reduction, etc) Participate in the plant technology improvement work process to support the identification, characterization, and evaluation of improvement opportunities. Support / Lead the implementation of technology improvement projects through lab, pilot and scale-up work and process technology expertise. Document / review / implement the Technology Improvement Plan for active ingredients and intermediates Develop the test plan and lead raw material qualification May support the assessment of technical feasibility for alternative routes to active ingredients and intermediates Support Existing Production Leverage technical expertise to support quality incident and plant upset investigation and correction Provide technical information to support product specification change and regulatory documentation/changes Lead and execute research projects to fill business objectives. Own / maintain / update Technology Documentation for active ingredient and intermediates. Technology Packages for different purposes (PTM, RFI, RFP, RFQ) Documents research projects in reports (NetDoc reports) Document and share learnings broadly with R&D, Manufacturing, etc Provide improvement recommendations during pre-campaign planning Understand, collect and document campaign improvements (Vendor campaign reports) Understand Intellectual Property, competitive intelligence landscape and regulatory impact, and identifies opportunities for IP protection and generic defense strategy Remains current with literature to assure that the latest technology is either being implemented, or at least, evaluated/ understood. Qualifications and Job location masters in chemical engineering. PhD in Chemistry or Chemical Engineering is beneficial. A solid knowledge of organic synthesis theory and/ or chemical engineering principles. Greater than 5 years work experience in process development and/or production support is preferred.