Helex

Company Description Helex is a therapeutics company developing a new class of targeted medicines for genetic kidney diseases using its proprietary LNP drug delivery and AI-based drug design platforms. With a world-class team of scientists and drug developers, Helex operates from ASPIRE BioNEST, Hyderabad, India, and New York, USA, and is supported by Bayer Co.Lab Cambridge. Role Description This is a full-time on-site role located in Hyderabad, India. A Senior Scientist in Gene Editing at Helex will be responsible for leading research and development projects to advance the company's gene-editing technologies for renal applications. The day-to-day tasks will include designing and conducting experiments, analyzing data, collaborating with cross-functional teams, and staying up to date with the latest advancements in genome editing and genetic medicine. Qualifications & Experience PhD in Genetics, Molecular Biology, Biotechnology, or a related field, or relevant Master's with exceptional industry experience (over 10 years) 3-5 years of experience with gene editing techniques such as CRISPR/Cas9 or similar technologies, in both cell and animal models Strong expertise in i n vivo studies involving gene editing, including animal handling, dosing, and tissue analysis Proficiency in molecular and cellular biology assays (PCR, qPCR, ddPCR, ELISA, Western blot, flow cytometry, immunostaining). Experience in designing studies such as toxicology and PK/PD experiments, and executing internally and in collaboration with CROs Familiarity with GLP practices, IND-enabling workflows, and regulatory expectations for gene editing programs Excellent analytical skills, along with the ability to interpret complex data Ability to work collaboratively in a multi-disciplinary team environment Publications in peer-reviewed journals demonstrating impactful research Background in renal biology and kidney disease research preferred Experience in nanoparticle delivery systems and lipid nanoparticles is preferred, but not compulsory